메뉴 건너뛰기




Volumn 18, Issue 6, 2008, Pages 674-680

Long-term clinical impact of introducing a human papillomavirus 16/18 AS04 adjuvant cervical cancer vaccine in Spain

Author keywords

Mass screening; Papillomavirus vaccines; Spain; Uterine cervical neoplasms

Indexed keywords

ADJUVANT; WART VIRUS VACCINE;

EID: 56749092154     PISSN: 11011262     EISSN: 1464360X     Source Type: Journal    
DOI: 10.1093/eurpub/ckn064     Document Type: Article
Times cited : (16)

References (53)
  • 1
    • 33846584559 scopus 로고    scopus 로고
    • The epidemiology of human papillomavirus infection and its association with cervical cancer
    • Bosch FX, Qiao YL, Castellsagué X. The epidemiology of human papillomavirus infection and its association with cervical cancer. Int J Gynaecol Obstet 2006;94(Suppl 1):S8-S21.
    • (2006) Int J Gynaecol Obstet , vol.94 , Issue.SUPPL. 1
    • Bosch, F.X.1    Qiao, Y.L.2    Castellsagué, X.3
  • 2
    • 0141925768 scopus 로고    scopus 로고
    • Cervical human papillomavirus infection in the female population in Barcelona, Spain
    • de Sanjosé S, Almirall R, Lloveras B, et al. Cervical human papillomavirus infection in the female population in Barcelona, Spain. Sex Transm Dis 2003;30:788-93.
    • (2003) Sex Transm Dis , vol.30 , pp. 788-793
    • de Sanjosé, S.1    Almirall, R.2    Lloveras, B.3
  • 3
    • 10544234613 scopus 로고    scopus 로고
    • Risk factors for HPV DNA detection in middle-aged women
    • Munoz N, Kato I, Bosch FX, et al. Risk factors for HPV DNA detection in middle-aged women. Sex Transm Dis 1996;23:504-10.
    • (1996) Sex Transm Dis , vol.23 , pp. 504-510
    • Munoz, N.1    Kato, I.2    Bosch, F.X.3
  • 4
    • 56749097395 scopus 로고    scopus 로고
    • Estimation of the human papillomavirus risks and regressionprogression times [in Spanish]
    • Cáceres, Spain: 27-29 October
    • Font R. Estimation of the human papillomavirus risks and regressionprogression times [in Spanish]. XXII Annual Meeting of the Spanish Society of Epidemiology, Cáceres, Spain: 27-29 October 2004.
    • (2004) XXII Annual Meeting of the Spanish Society of Epidemiology
    • Font, R.1
  • 5
    • 33745119463 scopus 로고    scopus 로고
    • Higher prevalence of human papillomavirus infection in migrant women from Latin America in Spain
    • Gonzalez C, Ortiz M, Canals J, et al. Higher prevalence of human papillomavirus infection in migrant women from Latin America in Spain. Sex Transm Infect 2006;82:260-2.
    • (2006) Sex Transm Infect , vol.82 , pp. 260-262
    • Gonzalez, C.1    Ortiz, M.2    Canals, J.3
  • 6
    • 34250736244 scopus 로고    scopus 로고
    • Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: A meta-analysis
    • de Sanjose S, Diaz M, Castellsague X, et al. Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysis. Lancet Infect Dis 2007;7:453-9.
    • (2007) Lancet Infect Dis , vol.7 , pp. 453-459
    • de Sanjose, S.1    Diaz, M.2    Castellsague, X.3
  • 7
    • 56749157220 scopus 로고    scopus 로고
    • Globocan 2002: Cancer Incidence, Mortality and Prevalence Worldwide. Available from: http://www-dep.iarc.fr (date last accessed 20 February 2006).
    • Globocan 2002: Cancer Incidence, Mortality and Prevalence Worldwide. Available from: http://www-dep.iarc.fr (date last accessed 20 February 2006).
  • 9
    • 41449088682 scopus 로고    scopus 로고
    • Age at sexual initiation and number of sexual partners in the female Spanish population. Results from the AFRODITA survey
    • May 20, Epub ahead of print
    • de Sanjosé S, Cortés X, Méndez C, et al. Age at sexual initiation and number of sexual partners in the female Spanish population. Results from the AFRODITA survey. Eur J Obstet Gynecol Reprod Biol 2008 May 20. [Epub ahead of print].
    • (2008) Eur J Obstet Gynecol Reprod Biol
    • de Sanjosé, S.1    Cortés, X.2    Méndez, C.3
  • 10
    • 0037421589 scopus 로고    scopus 로고
    • Epidemiologic classification of human papillomavirus types associated with cervical cancer
    • Munoz N, Bosch FX, de Sanjosé S, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Eng J Med 2003;348:518-27.
    • (2003) N Eng J Med , vol.348 , pp. 518-527
    • Munoz, N.1    Bosch, F.X.2    de Sanjosé, S.3
  • 11
    • 33646058566 scopus 로고    scopus 로고
    • Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: Follow-up from a randomised control trial
    • Harper DM, Franco EL, Wheeler CM, et al. Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial. Lancet 2006;367:1247-55.
    • (2006) Lancet , vol.367 , pp. 1247-1255
    • Harper, D.M.1    Franco, E.L.2    Wheeler, C.M.3
  • 13
    • 34250850161 scopus 로고    scopus 로고
    • Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: An interim analysis of a phase III double-blind, randomised controlled trial
    • Paavonen J, Jenkins D, Bosch F, et al. Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial. Lancet 2007;369:2161-70.
    • (2007) Lancet , vol.369 , pp. 2161-2170
    • Paavonen, J.1    Jenkins, D.2    Bosch, F.3
  • 14
    • 45849152355 scopus 로고    scopus 로고
    • Sustained immunogenicity and high efficacy against HPV-16/18 related cervical neoplasia: Long-term follow up through 6.4 years in women vaccinated with Cervarix (GSKs HPV 16/18 AS04 candidate vaccine)
    • March
    • Harper DM, Gall S, Naud P, et al. Sustained immunogenicity and high efficacy against HPV-16/18 related cervical neoplasia: long-term follow up through 6.4 years in women vaccinated with Cervarix (GSKs HPV 16/18 AS04 candidate vaccine). Miami, Florida, USA: Society of Gynecologic Oncologists (SGO) Conference (9 March 2008).
    • (2008) Miami, Florida, USA: Society of Gynecologic Oncologists (SGO) Conference (9
    • Harper, D.M.1    Gall, S.2    Naud, P.3
  • 15
    • 2342613014 scopus 로고    scopus 로고
    • Projected clinical benefits and costeffectiveness of a human papillomavirus 16/18 vaccine
    • Goldie SJ, Kohli M, Grima D, et al. Projected clinical benefits and costeffectiveness of a human papillomavirus 16/18 vaccine. J Natl Cancer Inst 2004;96:604-15.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 604-615
    • Goldie, S.J.1    Kohli, M.2    Grima, D.3
  • 16
    • 17844391859 scopus 로고    scopus 로고
    • Natural history and screening model for high-risk human papillomavirus infection, neoplasia and cervical cancer in the Netherlands
    • Berkhof J, de Bruijne MC, Zielinski GD, Meijer CJ. Natural history and screening model for high-risk human papillomavirus infection, neoplasia and cervical cancer in the Netherlands. Int J Cancer 2005;115:268-75.
    • (2005) Int J Cancer , vol.115 , pp. 268-275
    • Berkhof, J.1    de Bruijne, M.C.2    Zielinski, G.D.3    Meijer, C.J.4
  • 17
    • 33644860830 scopus 로고    scopus 로고
    • Evaluation of cervical screening strategies with adjunct high-risk human papillomavirus testing for women with borderline or mild dyskaryosis
    • Berkhof J, de Bruijne MC, Zielinski GD, et al. Evaluation of cervical screening strategies with adjunct high-risk human papillomavirus testing for women with borderline or mild dyskaryosis. Int J Cancer 2006;118:1759-68.
    • (2006) Int J Cancer , vol.118 , pp. 1759-1768
    • Berkhof, J.1    de Bruijne, M.C.2    Zielinski, G.D.3
  • 18
    • 56749165723 scopus 로고    scopus 로고
    • Coverage and factors associated with cervical cancer screening results from the AFRODITA study, a population-based survey in Spain
    • Prague, Czech Republic, 1-7 September
    • Castellsagué X. Coverage and factors associated with cervical cancer screening results from the AFRODITA study, a population-based survey in Spain. 23rd International Papillomavirus Conference: Prague, Czech Republic, 1-7 September 2006.
    • (2006) 23rd International Papillomavirus Conference
    • Castellsagué, X.1
  • 19
    • 0031912232 scopus 로고    scopus 로고
    • Positive predictive rate of colposcopic examination of the cervix uteri: An overview of literature
    • Hopman EH, Kenemans P, Helmerhorst TJ. Positive predictive rate of colposcopic examination of the cervix uteri: an overview of literature. Obstet Gynecol Surv 1998;53:97-106.
    • (1998) Obstet Gynecol Surv , vol.53 , pp. 97-106
    • Hopman, E.H.1    Kenemans, P.2    Helmerhorst, T.J.3
  • 20
    • 56749155191 scopus 로고    scopus 로고
    • Spanish Society of Cytology (SEC), Spanish Association of Colposcopy and Cervical Pathology (AEPCC)
    • Spanish Society of Obstetrics and Gynecology SEGO, in Spanish, Consensus document
    • Spanish Society of Obstetrics and Gynecology (SEGO), Spanish Society of Cytology (SEC), Spanish Association of Colposcopy and Cervical Pathology (AEPCC). Human papillomavirus infection [in Spanish]. Consensus document, 2002.
    • (2002) Human papillomavirus infection
  • 21
    • 41449117899 scopus 로고    scopus 로고
    • Coverage and factors associated with cervical cancer screening: Results from the AFRODITA study: a population-based survey in Spain
    • Puig-Tintoré LM, Castellsagué X, Torne A, et al. Coverage and factors associated with cervical cancer screening: results from the AFRODITA study: a population-based survey in Spain. J Low Genit Tract Dis 2008;12:82-9.
    • (2008) J Low Genit Tract Dis , vol.12 , pp. 82-89
    • Puig-Tintoré, L.M.1    Castellsagué, X.2    Torne, A.3
  • 22
    • 56749169985 scopus 로고    scopus 로고
    • Rash RM, Torné A, Castro M, et al. Evaluating the costs of follow-up and treatment of women with abnormal cervical cytology in Spain. 244. 2007. Barcelona, Spain, Book of Abstracts, IV Annual Meeting Health Technology Assessment International (HTAi) (17 June 2007).
    • Rash RM, Torné A, Castro M, et al. Evaluating the costs of follow-up and treatment of women with abnormal cervical cytology in Spain. 244. 2007. Barcelona, Spain, Book of Abstracts, IV Annual Meeting Health Technology Assessment International (HTAi) (17 June 2007).
  • 23
    • 56749184780 scopus 로고    scopus 로고
    • Comparing management patterns and associated costs for women with abnormal cervical cytology in 5 different countries
    • October
    • Rash B, Van Kriekinge G, Standaert B. Comparing management patterns and associated costs for women with abnormal cervical cytology in 5 different countries. Copenhagen, DK: ISPOR 9th Annual European Congress (28 October 2006).
    • (2006) Copenhagen, DK: ISPOR 9th Annual European Congress (28
    • Rash, B.1    Van Kriekinge, G.2    Standaert, B.3
  • 24
    • 0042345044 scopus 로고    scopus 로고
    • Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: A meta-analysis
    • Clifford GM, Smith JS, Aguado T, Franceschi S. Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: a meta-analysis. Br J Cancer 2003;89:101-5.
    • (2003) Br J Cancer , vol.89 , pp. 101-105
    • Clifford, G.M.1    Smith, J.S.2    Aguado, T.3    Franceschi, S.4
  • 25
    • 0037434411 scopus 로고    scopus 로고
    • Human papillomavirus types in invasive cervical cancer worldwide: A meta-analysis
    • Clifford GM, Smith JS, Plummer M, et al. Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis. Br J Cancer 2003;88:63-73.
    • (2003) Br J Cancer , vol.88 , pp. 63-73
    • Clifford, G.M.1    Smith, J.S.2    Plummer, M.3
  • 26
    • 18544380961 scopus 로고    scopus 로고
    • Human papillomavirus genotype distribution in low-grade cervical lesions: Comparison by geographic region and with cervical cancer
    • Clifford GM, Rana RK, Franceschi S, et al. Human papillomavirus genotype distribution in low-grade cervical lesions: comparison by geographic region and with cervical cancer. Cancer Epidemiol Biomarkers Prev 2005;14:1157-64.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 1157-1164
    • Clifford, G.M.1    Rana, R.K.2    Franceschi, S.3
  • 27
    • 24944504307 scopus 로고    scopus 로고
    • Worldwide distribution of human papillomavirus types in cytologically normal women in the International Agency for Research on Cancer HPV prevalence surveys: A pooled analysis
    • Clifford GM, Gallus S, Herrero R, et al. Worldwide distribution of human papillomavirus types in cytologically normal women in the International Agency for Research on Cancer HPV prevalence surveys: a pooled analysis. Lancet 2005;366:991-8.
    • (2005) Lancet , vol.366 , pp. 991-998
    • Clifford, G.M.1    Gallus, S.2    Herrero, R.3
  • 28
    • 27744581082 scopus 로고    scopus 로고
    • Data collected at the Hospital Creu Roja of L'Hospitalet, Spain
    • Data collected at the Hospital Creu Roja of L'Hospitalet, Barcelona (Spain). 1999.
    • (1999) Barcelona
  • 30
    • 0141769381 scopus 로고    scopus 로고
    • Available at:, Accessed 20 February 2006
    • Globocan 2002 Database. Available at: http://www-dep.iarc.fr (Accessed 20 February 2006).
    • (2002) Database
    • Globocan1
  • 33
    • 56749180083 scopus 로고    scopus 로고
    • Spanish National Statistics Institute INE, Available at
    • Spanish National Statistics Institute (INE) 2004. Deaths according to causes by age group and sex in 2003. Available at: http://www.ine.es/inebase/ index.html.
    • (2004) Deaths according to causes by age group and sex in 2003
  • 34
    • 33846242622 scopus 로고    scopus 로고
    • Estimating the long-term impact of the prophylactic human papillomavirus 16/18 vaccine on the burden of cervical cancer in the UK
    • Kohli M, Ferko N, Martin A, et al. Estimating the long-term impact of the prophylactic human papillomavirus 16/18 vaccine on the burden of cervical cancer in the UK. Br J Cancer 2007;96:143-50.
    • (2007) Br J Cancer , vol.96 , pp. 143-150
    • Kohli, M.1    Ferko, N.2    Martin, A.3
  • 35
    • 8444249386 scopus 로고    scopus 로고
    • Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: A randomised controlled trial
    • Harper DM, Franco EL, Wheeler C, et al. Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial. Lancet 2004;364:1757-65.
    • (2004) Lancet , vol.364 , pp. 1757-1765
    • Harper, D.M.1    Franco, E.L.2    Wheeler, C.3
  • 37
    • 56749174314 scopus 로고    scopus 로고
    • Available from:, Accessed 9 November 2007
    • INE. Encuesta de Salud y Hábitos Sexuales 2003. Available from: http://www.ine.es/prodyser/pubweb/saludyhs03/saludyhs03.htm (Accessed 9 November 2007).
    • (2003)
  • 38
    • 56749150155 scopus 로고    scopus 로고
    • Spanish National Statistics Institute INE, Available at:, Accessed 7 February 2007
    • Spanish National Statistics Institute (INE) 2004. Population data by age group and sex in 2003. Available at: http://www.ine.es/inebase/index.html. (Accessed 7 February 2007).
    • (2004) Population data by age group and sex in 2003
  • 39
    • 34548453304 scopus 로고    scopus 로고
    • Substantial impact on precancerous lesions and HPV infections through 5.5 years in women vaccinated with the HPV-16/18 VLP AS04 candidate vaccine
    • Presented at the, Los Angeles, CA, 14-18 April, Abstract 4900
    • Gall SA, Teixeira J, Wheeler WM, et al. Substantial impact on precancerous lesions and HPV infections through 5.5 years in women vaccinated with the HPV-16/18 VLP AS04 candidate vaccine. Presented at the 2007 meeting of the American Association for Cancer Research (AACR), Los Angeles, CA, 14-18 April 2007. Abstract 4900.
    • (2007) 2007 meeting of the American Association for Cancer Research (AACR)
    • Gall, S.A.1    Teixeira, J.2    Wheeler, W.M.3
  • 41
    • 56749139748 scopus 로고    scopus 로고
    • Estimating the long-term health and economic impact of a prophylactic human papillomavirus (HPV) 16/18 vaccine with cross-protection on the burden of cervical disease in Italy
    • Dublin, Ireland: 22 October
    • Ferko N, Debicki D, Bamfi F, et al. Estimating the long-term health and economic impact of a prophylactic human papillomavirus (HPV) 16/18 vaccine with cross-protection on the burden of cervical disease in Italy. ISPOR 10th Annual European Congress, Dublin, Ireland: 22 October 2007.
    • (2007) ISPOR 10th Annual European Congress
    • Ferko, N.1    Debicki, D.2    Bamfi, F.3
  • 42
    • 56749157219 scopus 로고    scopus 로고
    • A cost-effective analysis of a human papillomavirus (HPV) 16/18 vaccine with cross-protection benefit in Germany
    • Dublin, Ireland: 22 October
    • Siebert U, Schwarz TF, Schneider A, et al. A cost-effective analysis of a human papillomavirus (HPV) 16/18 vaccine with cross-protection benefit in Germany. ISPOR 10th Annual European Congress, Dublin, Ireland: 22 October 2007.
    • (2007) ISPOR 10th Annual European Congress
    • Siebert, U.1    Schwarz, T.F.2    Schneider, A.3
  • 43
    • 0042661252 scopus 로고    scopus 로고
    • Potential health and economic impact of adding a human papillomavirus vaccine to screening programs
    • Kulasingam SL, Myers ER. Potential health and economic impact of adding a human papillomavirus vaccine to screening programs. JAMA 2003;290:781-9.
    • (2003) JAMA , vol.290 , pp. 781-789
    • Kulasingam, S.L.1    Myers, E.R.2
  • 44
    • 56749184427 scopus 로고    scopus 로고
    • Reduction in the risk of cervical cancer by vaccination against human papillomavirus - a health technology assessment
    • Danish Centre for Health Technology Assessment
    • Danish Centre for Health Technology Assessment. Reduction in the risk of cervical cancer by vaccination against human papillomavirus - a health technology assessment. Health Technol Assess 2007;9:79-96.
    • (2007) Health Technol Assess , vol.9 , pp. 79-96
  • 45
    • 77950520956 scopus 로고    scopus 로고
    • Health Technology Assessment Della Vaccinazione Anti-HPV
    • La Torre G. Health Technology Assessment Della Vaccinazione Anti-HPV. Italian J Public Health 2007;4:55-81.
    • (2007) Italian J Public Health , vol.4 , pp. 55-81
    • La Torre, G.1
  • 46
    • 3342938561 scopus 로고    scopus 로고
    • An evaluation of liquid-based cytology and human papillomavirus testing within the UK cervical cancer screening programme
    • Sherlaw-Johnson C, Philips Z. An evaluation of liquid-based cytology and human papillomavirus testing within the UK cervical cancer screening programme. Br J Cancer 2004;91:84-91.
    • (2004) Br J Cancer , vol.91 , pp. 84-91
    • Sherlaw-Johnson, C.1    Philips, Z.2
  • 48
    • 33748761925 scopus 로고    scopus 로고
    • The burden of HPV-related cancers
    • Parkin DM, Bray F. The burden of HPV-related cancers. Vaccine 2006;24(Suppl 3):S11-25.
    • (2006) Vaccine , vol.24 , Issue.SUPPL. 3
    • Parkin, D.M.1    Bray, F.2
  • 49
    • 0033573302 scopus 로고    scopus 로고
    • Evaluating the cost-effectiveness of vaccination programmes: A dynamic perspective
    • Edmunds WJ, Medley GF, Nokes DJ. Evaluating the cost-effectiveness of vaccination programmes: a dynamic perspective. Stat Med 1999;18:3263-82.
    • (1999) Stat Med , vol.18 , pp. 3263-3282
    • Edmunds, W.J.1    Medley, G.F.2    Nokes, D.J.3
  • 50
    • 16844368575 scopus 로고    scopus 로고
    • Trends in cervical squamous cell carcinoma incidence in 13 European countries: Changing risk and the effects of screening
    • Bray F, Loos AH, McCarron P, et al. Trends in cervical squamous cell carcinoma incidence in 13 European countries: changing risk and the effects of screening. Cancer Epidemiol Biomarkers Prev 2005;14:677-86.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 677-686
    • Bray, F.1    Loos, A.H.2    McCarron, P.3
  • 52
    • 0028840912 scopus 로고    scopus 로고
    • Psychological response to cervical screening
    • Bell S, Porter M, Kitchener H, et al. Psychological response to cervical screening. Prev Med 1999;24:610-6.
    • (1999) Prev Med , vol.24 , pp. 610-616
    • Bell, S.1    Porter, M.2    Kitchener, H.3
  • 53
    • 33747892271 scopus 로고    scopus 로고
    • Issues in planning cervical cancer screening in the era of HPV vaccination
    • Franco EL, Cuzick J, Hildesheim A, de Sanjosé S. Issues in planning cervical cancer screening in the era of HPV vaccination. Vaccine 2006;24(Suppl 3):S171-7.
    • (2006) Vaccine , vol.24 , Issue.SUPPL. 3
    • Franco, E.L.1    Cuzick, J.2    Hildesheim, A.3    de Sanjosé, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.