Enhanced proliferation of SNU-407 human colon cancer cells by muscarinic acetylcholine receptors

Journal of Biochemistry and Molecular Biology

Volumn 41, Issue 11, 2008, Pages 803-807

  Park, Yang Seo ^a   Nam, Jeong Cho ^a  

^a Chungbuk National University   (South Korea)

Author keywords

Cell proliferation; Colon cancer cell line; ERK1 2; Muscarinic acetylcholine receptors

Indexed keywords

EID: 56649123513     PISSN: 12258687     EISSN: 02191024     Source Type: Journal    
DOI: 10.5483/bmbrep.2008.41.11.803     Document Type: Article

References (18)

1. Smith G., Carey F. A., Beattie J., Wilkie M. J. V., Lightfoot T. J., Coxhead J., Garner R. C., Steele R. J. C. and Wolf C. R. (2002) Mutations in APC, Kirsten-ras, and p53 - alternative genetic pathways to colorectal cancer. Proc. Natl. Acad. Sci. USA 99, 9433-9438.
2. Nathanson N. M. (1987) Molecular properties of the muscarinic acetylcholine receptor. Annu. Rev. Neurosci. 10, 195-236.
3. Frucht H., Jensen R. T., Dexter D., Yang W.-L. and Xiao Y. (1999) Human colon cancer cell proliferation mediated by the M3 muscarinic cholinergic receptor. Clin. Cancer Res. 5, 2532-2539.
4. Li B.-S., Ma W., Zhang L., Barker J. L., Stenger D. A. and Pant H. C. (2001) Activation of phosphatidylinositol-3 kinase (PI-3K) and extracellular regulated kinases (Erk1/2) is involved in muscarinic receptor-mediated DNA synthesis in neural progenitor cells. J. Neurosci. 21, 1569-1579.
5. Jimenez E. and Montiel M. (2005) Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells. J. Cell Physiol. 204, 678-686.
6. Matthiesen S., Bahulayan A., Kempkens S., Haag S., Fuhrmann M., Stichnote C., Juergens U. R. and Racke K. (2006) Muscarinic receptors mediate stimulation of human lung fibroblast proliferation. Am. J. Respir. Cell Mol. Biol. 35, 621-627.
7. Bonner T. I., Buckley N. J, Young A. C. and Brann M. R. (1987) Identification of a family of muscarinic acetylcholine receptor genes. Science 237, 527-532.
8. Bonner T. I., Young A. C., Brann M. R. and Buckley N. J. (1988) Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes. Neuron 1, 403-410.
9. Ashkenazi A., Ramachandran J. and Capon D. J. (1989) Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes. Nature 340, 146-150.
10. Kopp R., Lambrecht G., Mutschler E., Moser U., Tacke R. and Pfeiffer A. (1989) Human HT-29 colon carcinoma cells contain muscarinic M3 receptors coupled to phosphoinositide metabolism. Eur. J. Pharmacol. 172, 397-405.
11. Dickinson K. E. J., Frizzell R. A. and Sekar M. C. (1992) Activation of T84 cell chloride channels by carbachol involves a phosphoinositide-coupled muscarinic M3 receptor. Eur. J. Pharmacol. 225, 291-298.
12. Yang W.-L. and Frucht H. (2000) Cholinergic receptor up-regulates COX-2 expression and prostaglandin E2 production in colon cancer cells. Carcinogenesis 21, 1789-1793.
13. Cheng K., Zimniak P. and Raufman J.-P. (2003) Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells. Cancer Res. 63, 6744-6750.
14. Ukegawa J.-I., Takeuchi Y., Kusayanagi S. and Mitamura K. (2003) Growth-promoting effect of muscarinic acetylcholine receptors in colon cancer cells. J. Cancer Res. Clin. Oncol. 129, 272-278.
15. Oh J.-H., Ku J.-L., Yoon K.-A., Kwon H.-J., Kim W.-H., Park H.-S., Yeo K.-S., Song S.-Y., Chung J.-K. and Park J.-G. (1999) Establishment and characterization of 12 human colorectal-carcinoma cell lines. Int. J. Cancer 81, 902-910.
16. Chambard J.-C., Lefloch R., Pouyssegur J. and Lenormand P. (2007) ERK implication in cell cycle regulation. Biochim. Biophys. Acta 1773, 1299-1310.
17. Marshall C. J. (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185.
18. Meloche S. and Pouyssegur J. (2007) The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 26, 3227-3239.