A critical GxxxA motif in the γ6 calcium channel subunit mediates its inhibitory effect on Cav3.1 calcium current

Journal of Physiology

Volumn 586, Issue 22, 2008, Pages 5349-5366

  Lin, Zuojun ^a   Witschas, Katja ^b   Garcia, Thomas ^a   Chen, Ren Shiang ^a   Hansen, Jared P ^a   Sellers, Zachary M ^a,c   Kuzmenkina, Elza ^b   Herzig, Stefan ^b   Best, Philip M ^a,c,d  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL GAMMA SUBUNIT 6; HELIX LOOP HELIX PROTEIN; MEMBRANE PROTEIN; MEMBRANE PROTEIN 1; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL CAV3.1; CALCIUM CHANNEL ALPHA 3.1; CALCIUM CHANNEL CAV3.1; CALCIUM CHANNEL GAMMA 6 SUBUNIT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CURRENT; CHIMERA; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INHIBITION KINETICS; KIDNEY CELL; MOLECULAR MECHANICS; MUSCLE CELL; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM; ADULT; AMINO TERMINAL SEQUENCE; ATRIAL MYOCYTE; CARBOXY TERMINAL SEQUENCE; FIRST TRANSMEMBRANE DOMAIN; GENETIC TRANSFECTION; GXXXA MOTIF; HEK293 CELL LINE; HELIX HELIX INTERACTION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PROTEIN ANALYSIS; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; ANIMALS; CALCIUM CHANNELS; CALCIUM CHANNELS, T-TYPE; CELL LINE; ELECTROPHYSIOLOGY; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MYOCYTES, CARDIAC; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 56649113035     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2008.159111     Document Type: Article

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