Genetic polymorphism c.1438A>G of the 5-HT2A receptor is associated with abdominal obesity in Chinese Northern Han population

Molecular Biology Reports

Volumn 36, Issue 1, 2009, Pages 91-95

  Ying, Su ^a   Liu, Xiao Min ^a   Sun, Yan Ming ^a   Pan, Shang Ha ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

5 HT2A receptor gene; c.1438A>G; Obesity; Promoter; Restriction fragment length polymorphism

Indexed keywords

GENE PRODUCT; SEROTONIN 2A RECEPTOR;

ABDOMINAL OBESITY; ADULT; ALLELE; ARTICLE; BODY FAT; BODY MASS; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; GLUCOSE METABOLISM; HUMAN; INSULIN METABOLISM; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; WAIST CIRCUMFERENCE; WAIST HIP RATIO;

ABDOMINAL FAT; ADULT; ANALYSIS OF VARIANCE; BLOOD GLUCOSE; BODY WEIGHTS AND MEASURES; CHINA; CHOLESTEROL; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; INSULIN; MALE; MIDDLE AGED; OBESITY; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROMOTER REGIONS, GENETIC; RECEPTOR, SEROTONIN, 5-HT2A; SEX FACTORS; TRIGLYCERIDES;

EID: 56649086662     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-007-9155-6     Document Type: Article

References (14)

1. FX Pi-Sunyer 2002 The obesity epidemic: pathophysiology and consequences of obesity Obes Res 10 97S 104S
2. GA Bray 2004 Medical consequences of obesity J Clin Endocrinol Metab 89 2583 2589
3. TG Dinan 1996 Serotonin and the regulation of hypothalamic-pituitary- adrenal axis function Life Sci 58 1683 1694
4. P Bjorntorp R Rosmond 2000 Obesity and cortisol Nutrition 16 924 936
5. L Tilzer S Thomas RF Moreno 1989 Use of silica gel polymer for DNA extraction with organic solvents Anal Biochem 183 13 15
6. 2A receptor gene promoter Ann NY Acad Sci 967 571 575
7. 2A receptor gene polymorphism and eating disorders Neurosci Lett 323 105 108
8. 2A receptor gene polymorphism is associated with food and alcohol intake in obese people Int J Obes Relat Metab Disord 24 7 920 924
9. B Herbeth E Aubry F Fumeron R Aubert F Cailotto G Siest S Visvikis-Siest 2005 Polymorphism of the 5-HT2A receptor gene and food intakes in children and adolescents: the Stanislas Family Study Am J Clin Nutr 82 467 470
10. J Vague 1999 The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout and uric calculous disease Nutrition 15 89 90
11. L Lapidus C Bengtsson B Larsson K Penner E Rybo L Sjostrom 1984 Distribution of adipose tissue and risk of cardiovascular disease and death: a 12-year follow-up of participants in the population study of women in Gothenburg, Sweden Br Med J 289 1257 1261
12. GM Reaven 1988 Banting Lecture 1988: role of insulin resistance in human disease Diabetes 37 1595 1607
13. R Rosmond P Bjorntorp 2000 The role of antidepressants in the treatment of abdominal obesity Med Hypotheses 54 990 994
14. RJ Wurtman JJ Wurtman 1995 Brain serotonin, carbohydrate-craving, obesity and depression Obes Res 3 477s 480s