Metformin therapy for gestational diabetes mellitus: Are we there yet?

Nature Clinical Practice Endocrinology and Metabolism

Volumn 4, Issue 12, 2008, Pages 654-655

  Feig, Denice S ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Gestational diabetes mellitus; Insulin; Metformin; Pregnancy; Randomized controlled trial

Indexed keywords

GLIBENCLAMIDE; GLUCOSE; INSULIN; METFORMIN;

BODY FAT DISTRIBUTION; DRUG EFFICACY; DRUG SAFETY; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; HYPOGLYCEMIA; INSULIN SENSITIVITY; NEONATAL FAT DISTRIBUTION; NEONATAL HYPERINSULINEMIA; NEWBORN DISEASE; NEWBORN HYPOGLYCEMIA; PREGNANCY DIABETES MELLITUS; PREMATURITY; PREVALENCE; PRIORITY JOURNAL; SHORT SURVEY; SIDE EFFECT; TREATMENT OUTCOME; WEIGHT GAIN;

EID: 56649083551     PISSN: 17458366     EISSN: 17458374     Source Type: Journal    
DOI: 10.1038/ncpendmet0969     Document Type: Short Survey

References (7)

1. Ferrara A et al. (2004) An increase in the incidence of gestational diabetes mellitus: Northern California, 1991-2000. Obstet Gynecol 103: 526-533
2. Langer O et al. (2000) A comparison of glyburide and insulin in women with gestational diabetes mellitus. NEJM 343: 1134-1138
3. Khattab S et al. (2006) Metformin reduces abortion in pregnant women with polycystic ovary syndrome. Gynecol Endocrinol 22: 680-684
4. Rowan JA et al. (2008) Metformin versus insulin for the treatment of gestational diabetes. NEJM 358: 2003-2015
5. Kahn BF et al. (2006) Predictors of glyburide failure in the treatment of gestational diabetes. Obstet Gyncol 107: 1303-1309
6. Charles B et al. (2006) Population pharmacokinetics of metformin in late pregnancy. Ther Drug Monit 28: 67-72
7. Glueck CJ et al. (2004) Height, weight and motor-social development during the first 18 months of life in 126 infants born to 109 mothers with polycystic ovary syndrome who conceived on and continued metformin through pregnancy. Human Reprod 19: 1323-1330