HPLC method for the determination of bezafibrate in human plasma and application to a pharmacokinetic study of bezafibrate dispersible tablet

Journal of Chromatographic Science

Volumn 46, Issue 10, 2008, Pages 844-847

  Wei, Zhang ^a   Bing Ren, Xiang ^a   Ying, Zhan ^a   Liyan, Yu ^a   Teng, Wang ^a   Cai Yun, Wang ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 56549126150     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/46.10.844     Document Type: Article

References (11)

1. J.P. Monk and P.A. Todd. Bezafibrate: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hyperlipidemia. Drugs. 33: 539-76 (1987)
2. M. Leschke, M. Podder, J. Jehle, and E. Strauer. Influence of long-term bezafibrate therapy on lipid parameters, fibrinogen and plasma viscosity. In: E. Ernst, W. Koening, G.D.O. Lowe, T.W. Meade TW, Eds. Fibrinogen: A "New" Cardiovascular Risk Factor. Vienna: Blackwell MTV, 1993, pp. 380-83.
3. I.R. Jones, A. Swai, R. Taylor, M. Miller, M.F. Laker, and K.G. Alberti. Lowering of plasma glucose concentrations with bezafibrate in patients with moderately controlled NIDDM. Diabetes Care 13: 855-63 (1990)
4. T. Ushiroyama, K. Sakuma, and S. Nosaka. Effects of bezafibrate on HDL2/HDL3 ratio in postmenopausal hypertriglyceridemic women. J. Cardiovasc. Pharmacol. Ther. 11: 142-48 (2006)
5. K. Ohmoto, N. Yoshioka, and S. Yamamoto. Long-term effect of bezafibrate on parameters of hepatic fibrosis in primary biliary cirrhosis. J. Gastroenterol. 41: 502-503 (2006)
6. O. Ali, M.A. Khan, R. Obaid and S.W. Ahmed. Bioavailability study of tablet Bezafibrate 200mg (Lipocor). Pak. J. Pharm. Sci. 15: 35-42 (2002)
7. D. Castoldi, V. Monzani, and O. Tofanetti. Determination of bezafibrate in human plasma and urine by high-performance liquid chromatography. J. Chromatogr. 344: 259-65 (1985)
8. D.M. Lucas, A.C. Luis, H.R. Ricardo, and P.W. Jose. Determination of bezafibrate, ciprofibrate and fenofibric acid in human plasma by high-performance liquid chromatography. J. Chromatogr. 687: 437-42 (1996)
9. M. Farré, M. Petrovic, and D. Barceló. Recently developed GC/MS and LC/MS methods for determining NSAIDs in water samples. Anal. Bioanal. Chem. 387: 1203-14 (2007).
10. M. Gros, M. Petrovic, and D. Barceló. Multi-residue analytical methods using LC-tandem MS for the determination of pharmaceuticals in environmental and wastewater samples: a review. Anal. Bioanal. Chem. 386: 941-52 (2006).
11. D.G. Kleinbaum, L.L. Kupper, and A. Nizam. Applied Regression Analysis and Other Multivariable Methods, 3rd ed. K. E. Muller, Ed. Duxbury Press, Pacific Grove, USA, 1998, pp. 434-90.