Primary cutaneous mucormycosis in a lung transplant recipient: Case report and concise review of the literature

Transplant Infectious Disease

Volumn 10, Issue 6, 2008, Pages 419-425

  Page, A V ^a   Evans, A J ^a   Snell, L ^a   Liles, W C ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Lung transplantation; Mucormycosis; Posaconazole; Skin lesions; Zygomycosis

Indexed keywords

AMIKACIN; AMPHOTERICIN B; BASILIXIMAB; CYCLOSPORIN; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; POSACONAZOLE; PREDNISONE; STEROID;

ADULT; ANAMNESIS; ARTICLE; BACTERIAL ARTHRITIS; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DEBRIDEMENT; DIABETES MELLITUS; DRUG MEGADOSE; GRAFT FAILURE; GRAFT RECIPIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; LEG ISCHEMIA; LUNG TRANSPLANTATION; MALE; MUCORMYCOSIS; MUSCLE FLAP; PRIORITY JOURNAL; REPERFUSION INJURY; RESPIRATORY FAILURE; SILICOSIS; SKIN MUCORMYCOSIS; SKIN TRANSPLANTATION;

ADULT; ANTIBIOTICS, ANTIFUNGAL; DEBRIDEMENT; DERMATOMYCOSES; HUMANS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; LUNG TRANSPLANTATION; MALE; MUCORMYCOSIS; POSTOPERATIVE COMPLICATIONS; RHIZOPUS; SILICOSIS; TRIAZOLES;

EID: 56549113286     PISSN: 13982273     EISSN: 13993062     Source Type: Journal    
DOI: 10.1111/j.1399-3062.2008.00324.x     Document Type: Article

References (35)

1. Mitchell SJ, Gray J, Morgan MEI, Hocking MD, Durbin GM. Nosocomial infection with Rhizopus microsporus in preterm infants: association with wooden tongue depressors. Lancet 1996 348 : 441 443.
2. Johnson AS, Ranson M, Scarffe JH, Morgenstern GR, Shaw AJ, Oppenheim BA. Cutaneous infection with Rhizopus oryzae and Aspergillus niger following bone marrow transplantation. J Hosp Infect 1993 25 : 293 296.
3. Dickinson M, Kalayanamit T, Yang CA, Pomper GJ, Franco-Webb C, Rodman D. Cutaneous zygomycosis (mucormycosis) complicating endotracheal intubation. Chest 1998 114 : 340 342.
4. Roden MM, Zaoutis TE, Buchanan WL, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 2005 41 : 634 653.
5. Kontoyiannis DP, Lionakis MS, Lewis RE, et al. Zygomycosis in a tertiary-care cancer center in the era of Aspergillus-active antifungal therapy: a case-control observational study of 27 recent cases. J Infect Dis 2005 191 : 1350 1360.
6. Almyroudis NG, Sutton DA, Linden P, Rinaldi MG, Fung J, Kusne S. Zygomycosis in solid organ transplant recipients in a tertiary transplant center and review of the literature. Am J Transplant 2006 6 : 2365 2374.
7. Prabhu RM, Patel R. Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment. Clin Microbiol Infect 2004 10 (Suppl 1) : 31 47.
8. Alimagham M, Amini-Afshar S, Farahmand S, Pour-Kazemi A, Pour-Reza-Gholi F, Masood S. Frequency of infectious skin lesions in kidney transplant recipients. Urol J 2005 2 : 193 196.
9. Harada AS, Lau W. Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole. Hawaii Med J 2007 66 : 68 71.
10. Quinio D, Karam A, Leroy J-P, et al. Zygomycosis caused by Cunninghamella bertholletiae in a kidney transplant recipient. Med Mycol 2004 42 : 177 180.
11. Kerbaul F, Guidon C, Collart F, et al. Abdominal wall mucormycosis after heart transplantation. J Cardiothorac Vasc Anesth 2004 18 : 822 823.
12. Uckay I, Chalandon Y, Sartoretti P, et al. Invasive zygomycosis in transplant recipients. Clin Transplant 2007 21 : 577 582.
13. Boyd AS, Wiser B, Sams HH, King LE. Gangrenous cutaneous mucormycosis in a child with a solid organ transplant: a case report and review of the literature. Pediatr Dermatol 2003 20 : 411 415.
14. McGuire FR, Grinnan DC, Robbins M. Mucormycosis of the bronchial anastomosis: a case of successful medical treatment and historic review. J Heart Lung Transplant 2007 26 : 857 861.
15. Minz M, Sharma A, Kashyap R, et al. Isolated renal allograft arterial mucormycosis: an extremely rare complication. Nephrol Dial Transplant 2003 18 : 1034 1035.
16. Jimenez C, Lumbreras C, Aguado JM, et al. Successful treatment of Mucor infection after liver or pancreas-kidney transplantation. Transplantation 2002 73 : 476 480.
17. Baraia J, Munoz P, Bernaldo de Quiros JCL, Bouza E. Cutaneous mucormycosis in a heart transplant patient associated with a peripheral catheter. Eur J Clin Microbiol Infect Dis 1995 14 : 813 815.
18. Adriaenssens K, Jorens PG, Meuleman L, Jeuris W, Lambert J. A black necrotic skin lesion in an immunocompromised patient. Arch Dermatol 2000 136 : 1165 1170.
19. Andrews PA, Abbs IA, Koffman CG, Ogg CS, Williams DG. Mucormycosis in transplant recipients: possible case-case transmission and potentiation by cytomegalovirus. Nephrol Dial Transplant 1994 9 : 1194 1196.
20. Carpenter CF, Subramanian AK. Cutaneous zygomycosis (mucormycosis). N Engl J Med 1999 341 : 1891.
21. Chen YS, Chen CL, Liu PP, Chiang YC, Sun CK, Eng HL. Successful treatment of invasive mucormycosis following liver transplantation. Transplant Proc 1996 28 : 1708 1709.
22. Fisher J, Tuazon CU, Geelhoed GW. Mucormycosis in transplant patients. Am Surg 1980 46 : 315 322.
23. Hall JC, Brewer JH, Reed WA, Steinhaus DM, Watson KR. Cutaneous mucormycosis in a heart transplant patient. Cutis 1988 42 : 183 186.
24. Heinz T, Perfect J, Schell W, Ritter E, Ruff G, Serafin D. Soft-tissue fungal infections: surgical management of 12 immunocompromised patients. Plast Reconstr Surg 1996 97 : 1391 1399.
25. Marchevsky AM, Bottone EJ, Geller SA, Giger DK. The changing spectrum of disease, etiology, and diagnosis of mucormycosis. Hum Pathol 1980 11 : 457 464.
26. Marco del Pont J, De Cicco L, Gallo G, Llera J, De Santibanez E, D'Agostino D. Hepatic arterial thrombosis due to Mucor species in a child following orthotopic liver transplantation. Transpl Infect Dis 2000 2 : 33 35.
27. Naguib MT, Huycke MM, Pederson JA, Pennington LR, Burton ME, Greenfield RA. Apophysomyces elegans infection in a renal transplant recipient. Am J Kidney Dis 1995 26 : 381 384.
28. Norden G, Bjorck S, Persson H, Svalander C, Li X, Edebo L. Cure of zygomycosis caused by a lipase-producing Rhizopus rhizopodiformis strain in a renal transplant patient. Scand J Infect Dis 1991 23 : 377 382.
29. Wajszczuk CP, Dummer JS, Ho M, et al. Fungal infections in liver transplant recipients. Transplantation 1985 40 : 347 353.
30. Wilcken DEL, Mackie JD, Pussell BA, et al. An unusual infection after renal transplantation. Med J Aust 1986 145 : 513 517.
31. Wilson CB, Siber GR, O'Brien TF, Morgan AP. Phycomycotic gangrenous cellulites. A report of two cases and a review of the literature. Arch Surg 1976 111 : 532 538.
32. Woods SG, Elewski BE. Zosteriform zygomycosis. J Am Acad Dermatol 1995 32 : 357 361.
33. Losee JE, Selber J, Vega S, Hall C, Scott G, Serletti JM. Primary cutaneous mucormycosis: guide to surgical management. Ann Plast Surg 2002 49 : 385 390.
34. Kontoyiannis DP, Wessel VC, Bodey GP, Rolston KVI. Zygomycosis in the 1990s in a tertiary-care cancer center. Clin Infect Dis 2000 30 : 851 856.
35. van Burik J-AH, Hare RS, Solomon HF, Corrado ML, Kontoyiannis DP. Posaconazole is effective as salvage therapy in zygomycosis: a retrospective summary of 91 cases. Clin Infect Dis 2006 42 : e61 e65.