Effects of estradiol and progestogens on tumor-necrosis factor-α-induced changes of biochemical markers for breast cancer growth and metastasis

Gynecological Endocrinology

Volumn 24, Issue 10, 2008, Pages 576-579

  Seeger, Harald ^a   Wallwiener, Diethelm ^a   Mueck, Alfred O ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Estradiol; Human breast cancer cells; Progestogens; Tumor invasion; Tumor necrosis factor

Indexed keywords

ESTRADIOL; GELATINASE B; MEDROXYPROGESTERONE; MONOCYTE CHEMOTACTIC PROTEIN 1; NORETHISTERONE; PROGESTERONE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ARTICLE; BREAST CANCER; CANCER MODEL; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; SUPERNATANT;

BIOLOGICAL MARKERS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMOKINE CCL2; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; FEMALE; HUMANS; MATRIX METALLOPROTEINASE 9; MEDROXYPROGESTERONE 17-ACETATE; NEOPLASM METASTASIS; PROGESTINS; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 56549113095     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.1080/09513590802288267     Document Type: Article

References (16)

1. Kenemans P. Postmenopausal hormone therapy and breast cancer: what is the problem? Maturitas 2005;51:75-82.
2. Liotta LA, Stetler-Stevenson WG. Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res 1991;51:5054s-5059s.
3. Mantovani A. Tumor-associated macrophages in neoplastic progression: a paradigm for the in vivo function of chemokines. Lab Invest 1994;71:5-16.
4. Hagemann T, Robinson SC, Schulz M, Trümper L, Balkwill FR, Binder C. Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-α dependent up-regulation of matrix metalloproteases. Carcinogenesis 2004;25:1543-1549.
5. Carswell EA, Old LJ, Kassel RI, Green S, Fiore N, Williamson B. An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci U S A 1975;72:3666-3670.
6. Moore RJ, Owens DM, Stamp G, Arnott C, Burke F, East N, Holdsworth H, Turner L, Rollins B, Pasparakis M, et al. Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis. Nature Med 1999;5:828-831.
7. Malik STA, Naylor S, East N, Oliff A, Balkwill FR. Cells secreting tumor necrosis factor show enhanced metastasis in nude mice. Eur J Cancer 1990;26:1031-1034.
8. Orosz P, Kruger A, Hubbe M, Ruschoff J, Von Hoegen P, Mannel DN. Promotion of experimental liver metastasis by tumor necrosis factor. Int J Cancer 1995;60:867-871.
9. Robinson SC, Scott KA, Balkwill FR. Chemokine stimulation of monocyte matrix metalloproteinase-9 requires endogenous TNF-α. Eur J Immunol 2002;32:404-412.
10. Leber TM, Balkwill FR. Regulation of monocyte MMP-9 production by TNF-α and a tumour-derived soluble factor (MMPSF). Br J Cancer 1998;78:724-732.
11. Matsushima K, Larsen CG, DuBois GC, Oppenheim JJ. Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human monocytic cell line. J Exp Med 1989;169:1485-1490.
12. Rollins BJ. Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease. Mol Med Today 1996;2:198-204.
13. Oppenheim JJ, Zachariae COC, Mukaida N, Matsushuma K. Properties of the novel proinflammatory supergene 'intercrine' cytokine family. Annu Rev Immunol 1991;9:617-648.
14. Inadera H, Sekiya T, Yoshimura T, Matsushima K. Molecular analysis of the inhibition of monocyte chemoattractant protein-1 gene expression by estrogens and xenoestrogens in MCF-7 cells. Endocrinology 2000;141:50-59.
15. Nesbit M, Schaider H, Miller TH, Herlyn M. Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells. J Immunol 2001;166:6483-6490.
16. Harmey JH, Bouchier-Hayes D. Vascular endothelial growth factor (VEGF), a survival factor for tumor cells: implications for anti-angiogenic therapy. BioEssays 2002;24:280-283.