Mechanism of the prostanoid TP receptor agonist U46619 for inducing emesis in the ferret

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 378, Issue 6, 2008, Pages 655-661

  Kan, Kelvin K W ^a   Ngan, Man P ^a   Wai, Man K ^a   Rudd, John A ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

Area postrema; Emesis; Ferret; Nausea; Nucleus tractus solitarii; Prostanoid; Thromboxane; TP receptor; U46619; Vagus

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 3 (2 METHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; 5 FLUORO 2 METHOXY 1H INDOLE 3 CARBOXYLIC ACID 1 [2 (METHYLSULFONAMIDO)ETHYL] 4 PIPERIDINYLMETHYL ESTER; DOMPERIDONE; DROPERIDOL; METOCLOPRAMIDE; NEUROKININ 1 RECEPTOR ANTAGONIST; ONDANSETRON; PROMETHAZINE; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; PROSTANOID RECEPTOR; SCOPOLAMINE; SEROTONIN 4 RECEPTOR; SULPIRIDE; THROMBOXANE A2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIEMETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; FERRET; MALE; NONHUMAN; RECEPTOR UPREGULATION; VAGOTOMY; VOMITING;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ANIMALS; ANTIEMETICS; DISEASE MODELS, ANIMAL; FERRETS; METOCLOPRAMIDE; PIPERIDINES; RECEPTORS, THROMBOXANE; VAGOTOMY; VOMITING;

EID: 56549086716     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-008-0325-4     Document Type: Article

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