Synchronous occult cancers of the endometrium and fallopian tube in an MSH2 mutation carrier at time of prophylactic surgery

Gynecologic Oncology

Volumn 111, Issue 3, 2008, Pages 575-578

  Palma, Laura ^a   Marcus, Victoria ^a   Gilbert, Lucy ^a   Chong, George ^b   Foulkes, William D ^a,c  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Fallopian tube cancer; Lynch syndrome (HNPCC); Prophylactic surgery; Synchronous cancers

Indexed keywords

TAMOXIFEN;

ADULT; ARTICLE; CASE REPORT; COLONOSCOPY; COLOSTOMY; CURETTAGE; ENDOMETRIUM CANCER; FAMILIAL CANCER; FEMALE; GENE; GENE MUTATION; HUMAN; HYSTERECTOMY; INTRADUCTAL CARCINOMA; MASTECTOMY; MSH2 GENE; OCCULT CANCER; PRIORITY JOURNAL; RECTUM CANCER; RECTUM HEMORRHAGE; RECTUM RESECTION; UTERINE TUBE CARCINOMA;

ENDOMETRIAL NEOPLASMS; FALLOPIAN TUBE NEOPLASMS; FEMALE; HUMANS; MIDDLE AGED; MUTATION; MUTS HOMOLOG 2 PROTEIN; NEOPLASMS, MULTIPLE PRIMARY; PEDIGREE;

EID: 56449127145     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2008.08.002     Document Type: Article

References (18)

1. Fishel R., Lescoe M.K., Rao M.R., Copeland N.G., Jenkins N.A., Garber J., et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75 (1993) 1027-1038
2. Bronner C.E., Baker S.M., Morrison P.T., Warren G., Smith L.G., Lescoe M.K., et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368 (1994) 258-261
3. Miyaki M., Konishi M., Tanaka K., Kikuchi-Yanoshita R., Muraoka M., Yasuno M., et al. Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nat. Genet 17 (1997) 271-272
4. Nicolaides N.C., Papadopoulos N., Liu B., Wei Y.F., Carter K.C., Ruben S.M., et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature 371 (1994) 75-80
5. Aarnio M., Sankila R., Pukkala E., Salovaara R., Aaltonen L.A., de la Chapelle A., et al. Cancer risk in mutation carriers of DNA-mismatch-repair genes. Int. J. Cancer 81 (1999) 214-218
6. Dunlop M.G., Farrington S.M., Carothers A.D., Wyllie A.H., Sharp L., Burn J., et al. Cancer risk associated with germline DNA mismatch repair gene mutations. Hum. Mol. Genet 6 (1997) 105-110
7. Quehenberger F., Vasen H.F.A., and van Houwelingen H.C. Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment. J Med. Genet 42 (2005) 491-496
8. Schmeler K.M., Lynch H.T., Chen L.M., Munsell M.F., Soliman P.T., Clark M.B., et al. Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome. N. Eng. J. Med. 354 (2006) 261-269
9. Watson P., Bützow R., Lynch H.T., Mecklin J.P., Järvinen J.H., Vasen H.G., et al. The clinical features of ovarian cancer in hereditary nonpolyposis colorectal cancer. Gynecol. Oncol. 82 (2001) 223-228
10. Lu K.H., Dinh M., Kohlmann W., Watson P., Green J., Syngal S., et al. Gynecologic cancer as a "sentinel cancer" for women with hereditary nonpolyposis colorectal cancer syndrome. Obstet. Gynecol. 82 (2005) 223-228
11. Stewart S.L., Wike J.M., Foster S.L., and Michaud F. The incidence of primary fallopian tube cancer in the United States. Gynecol. Oncol. 107 (2007) 392-397
12. Finch A., Beiner M., Lubinski J., Lynch H.T., Moller P., Rosen B., et al. Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 mutation. JAMA 296 (2006) 185-192
13. Callahan M.J., Crum C.P., Medeiros F., Kindelberger D.W., Elvin J.A., Garber J.E., et al. Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction. J. Clin. Oncol. 25 (2007) 3985-3990
14. Eisner R.F., Nieberg R.K., and Berek J.S. Synchronous primary neoplasms of the female reproductive tract. Gynecol. Oncol. 33 (1989) 335-339
15. Soliman P.T., Slomovitz B.M., Broaddus R.R., Sun C.C., Oh J.C., Eifel P.J., et al. Synchronous primary cancers of the endometrium and ovary: a single institution review of 84 cases. Gynecol. Oncol. 94 (2004) 456-462
16. Soliman P.T., Broaddus R.R., Schmeler K.M., Daniels M.S., Gonzalez D., Slomovitz B.M., et al. Women with synchronous primary cancers of the endometrium and ovary: do they have Lynch syndrome?. J. Clin. Oncol. 23 (2005) 9344-9350
17. Lin W.M., Forgacs E., Warshal D.P., Yeh I.T., Martin J.S., Ashfaq R., et al. Loss of heterozygosity and mutational analysis of the PTEN/MMAC1 gene in synchronous endometrial and ovarian carcinomas. Clin. Cancer Res. 4 (1998) 2577-2583
18. Scully R.E., Young R.H., and Clement P.B. Tumors of the ovary, maldeveloped gonads, fallopian tube, and broad ligament. Atlas of tumor pathology (1998), Armed Forces Institute of Pathology, Bethesda, MD