Single-tube genotyping using a solid-phase method that combines α-phosphorothioate-mediated primer extension and ExoIII: Proof of concept with the F508del cystic fibrosis diagnosis

Molecular and Cellular Probes

Volumn 22, Issue 5-6, 2008, Pages 320-323

  Brugère, Jean François ^a   Gobron, Stéphane ^a   Baud, Eric ^a   Cailloux, Fabrice ^a  

^a Nucleica SA   (France)

Author keywords

CFTR; Cystic fibrosis; Genetic diagnosis; Mutation detection; SNP; Solid phase

Indexed keywords

DEOXYRIBONUCLEOTIDE; DNA; EXODEOXYRIBONUCLEASE III; PHOSPHOROTHIOIC ACID; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; CAPILLARY ELECTROPHORESIS; CYSTIC FIBROSIS; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL ELECTROPHORESIS; GENE; GENE DELETION; GENE LOCUS; GENE MUTATION; GENOME; GENOTYPE; HYDROLYSIS; MASS SPECTROMETER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOLID; TRANSMEMBRANE CONDUCTANCE REGULATOR GENE;

BASE SEQUENCE; CYSTIC FIBROSIS; DNA PRIMERS; EXODEOXYRIBONUCLEASES; GENOTYPE; HUMANS; MOLECULAR DIAGNOSTIC TECHNIQUES; MOLECULAR SEQUENCE DATA; PHOSPHATES; SEQUENCE ANALYSIS, DNA;

EID: 56449109751     PISSN: 08908508     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcp.2008.07.001     Document Type: Article

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