Respiratory rhythm of brainstem-spinal cord preparations: Effects of maturation, age, mass and oxygenation

Respiratory Physiology and Neurobiology

Volumn 164, Issue 3, 2008, Pages 429-440

  Fong, Angelina Y ^a   Corcoran, Andrea E ^a   Zimmer, M Beth ^b   Andrade, Denis V ^c   Milsom, William K ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b FERRIS STATE UNIVERSITY   (United States)

^c SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Hamster; Pons; Postnatal development; Rat; Respiratory rhythmogenesis

Indexed keywords

AGE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN STEM; BREATHING RATE; CONTROLLED STUDY; HAMSTER; LONGEVITY; MASS; MATURATION; MEDULLA OBLONGATA; NEWBORN; NONHUMAN; PERINATAL PERIOD; PONS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RAT; RESPIRATORY FUNCTION; SPECIES; SPINAL CORD; TIME; TISSUE OXYGENATION;

ACTION POTENTIALS; AGE FACTORS; AGING; ANESTHETICS, LOCAL; ANIMALS; ANIMALS, NEWBORN; BRAIN STEM; CRICETINAE; HYPERBARIC OXYGENATION; LONGEVITY; NEURAL PATHWAYS; PERIODICITY; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION; SPINAL CORD; TETRODOTOXIN;

EID: 56449102183     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2008.09.008     Document Type: Article

References (30)

1. Brockhaus J., Ballanyi K., Smith J.C., and Richter D.W. Microenvironment of respiratory neurons in the in vitro brainstem-spinal cord of neonatal rats. J. Physiol. 462 (1993) 421-445
2. Butt A.M., and Berry M. Oligodendrocytes and the control of myelination in vivo: new insights from the rat anterior medullary velum. J. Neurosci. Res. 59 (2000) 477-488
3. Clancy B., Darlington R.B., and Finlay B.L. Translating developmental time across mammalian species. Neuroscience 105 (2001) 7-17
4. Clancy B., Finlay B.L., Darlington R.B., and Anand K.J. Extrapolating brain development from experimental species to humans. Neurotoxicology 28 (2007) 931-937
5. Dutschmann M., Morschel M., Kron M., and Herbert H. Development of adaptive behaviour of the respiratory network: implications for the pontine Kolliker-Fuse nucleus. Resp. Physiol. Neurobiol. 143 (2004) 155-165
6. Errchidi S., Monteau R., and Hilaire G. Noradrenergic modulation of the medullary respiratory rhythm generator in the newborn rat: an in vitro study. J. Physiol. 443 (1991) 477-498
7. Finlay B.L., and Darlington R.B. Linked regularities in the development and evolution of mammalian brains. Science 268 (1995) 1578-1584
8. Guimaraes L., Dominguez-del-Toro E., Chatonnet F., Wrobel L., Pujades C., Monteiro L.S., and Champagnat J. Exposure to retinoic acid at the onset of hindbrain segmentation induces episodic breathing in mice. Eur. J. Neurosci. 25 (2007) 3526-3536
9. Hamano K., Takeya T., Iwasaki N., Nakayama J., Ohto T., and Okada Y. A quantitative study of the progress of myelination in the rat central nervous system, using the immunohistochemical method for proteolipid protein. Brain Res. Dev. Brain Res. 108 (1998) 287-293
10. Hare G.M., Harrington A., Liu E., Wang J.L., Baker A.J., and Mazer C.D. Effect of oxygen affinity and molecular weight of HBOCs on cerebral oxygenation and blood pressure in rats. Can. J. Anaesth. 53 (2006) 1030-1038
11. Hilaire G., Monteau R., and Errchidi S. Possible modulation of the medullary respiratory rhythm generator by the noradrenergic A5 area: an in vitro study in the newborn rat. Brain Res. 485 (1989) 325-332
12. Hilaire G., Viemari J.C., Coulon P., Simonneau M., and Bevengut M. Modulation of the respiratory rhythm generator by the pontine noradrenergic A5 and A6 groups in rodents. Resp. Physiol. Neurobiol. 143 (2004) 187-197
13. Hou H., Grinberg O.Y., Taie S., Leichtweis S., Miyake M., Grinberg S., Xie H., Csete M., and Swartz H.M. Electron paramagnetic resonance assessment of brain tissue oxygen tension in anesthetized rats. Anesth. Analg. 96 (2003) 1467-1472 table
14. Ito Y., Oyamada Y., Hakuno H., and Yamaguchi K. Morphological analysis of developmental changes in pontine noradrenergic neuronal groups in the neonatal rat. Brain Res. 925 (2002) 107-109
15. Janczewski W.A., and Feldman J.L. Distinct rhythm generators for inspiration and expiration in the juvenile rat. J. Physiol. 570 (2006) 407-420
16. Kron M., Morschel M., Reuter J., Zhang W., and Dutschmann M. Developmental changes in brain-derived neurotrophic factor-mediated modulations of synaptic activities in the pontine Kolliker-Fuse nucleus of the rat. J. Physiol. 583 (2007) 315-327
17. 2 response in conscious rats. J. Physiol. 577 (2006) 307-318
18. Liu Y.Y., and Wong-Riley M.T. Developmental study of cytochrome oxidase activity in the brain stem respiratory nuclei of postnatal rats. J. Appl. Physiol. 90 (2001) 685-694
19. Mellen N.M., Milsom W.K., and Feldman J.L. Hypothermia and recovery from respiratory arrest in a neonatal rat in vitro brain stem preparation. Am. J. Physiol. 282 (2002) R484-R491
20. Nwaigwe C.I., Roche M.A., Grinberg O., and Dunn J.F. Effect of hyperventilation on brain tissue oxygenation and cerebrovenous PO2 in rats. Brain Res. 868 (2000) 150-156
21. Onimaru H., and Homma I. A novel functional neuron group for respiratory rhythm generation in the ventral medulla. J. Neurosci. 23 (2003) 1478-1486
22. Pace R.W., Mackay D.D., Feldman J.L., and Del Negro C.A. Role of persistent sodium current in mouse preBotzinger Complex neurons and respiratory rhythm generation. J. Physiol. 580 (2007) 485-496
23. + antagonism of inspiratory centre rhythms in slices and en bloc preparations of newborn rat brainstem. J. Physiol. 584 (2007) 489-508
24. Sick T.J., Lutz P.L., LaManna J.C., and Rosenthal M. Comparative brain oxygenation and mitochondrial redox activity in turtles and rats. J. Appl. Physiol. 53 (1982) 1354-1359
25. Smith J.C., Greer J.J., Liu G.S., and Feldman J.L. Neural mechanisms generating respiratory pattern in mammalian brain stem-spinal cord in vitro. I. Spatiotemporal patterns of motor and medullary neuron activity. J. Neurophysiol. 64 (1990) 1149-1169
26. Suzue T. Respiratory rhythm generation in the in vitro brain stem-spinal cord preparation of the neonatal rat. J. Physiol. 354 (1984) 173-183
27. Tanabe A., Fujii T., and Onimaru H. Facilitation of respiratory rhythm by a mu-opioid agonist in newborn rat pons-medulla-spinal cord preparations. Neurosci. Lett. 375 (2005) 19-22
28. Tattersall G.J., and Milsom W.K. Hypothermia-induced respiratory arrest and recovery in neonatal rats. Resp. Physiol. Neurobiol. 137 (2003) 29-40
29. Viemari J.C., Burnet H., Bevengut M., and Hilaire G. Perinatal maturation of the mouse respiratory rhythm-generator: in vivo and in vitro studies. Eur. J. Neurosci. 17 (2003) 1233-1244
30. Zimmer M.B., and Milsom W.K. Effect of hypothermia on respiratory rhythm generation in hamster brainstem-spinal cord preparations. Resp. Physiol. Neurobiol. 142 (2004) 237-249