Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons

Cerebral Cortex

Volumn 18, Issue 12, 2008, Pages 2909-2919

  Lee, Cheol ^a   Gyorgy, Andrea ^a   Maric, Dragan ^b   Sadri, Navid ^c   Schneider, Robert J ^c   Barker, Jeffery L ^b   Lawson, Michael ^a   Agoston, Denes V ^a,d  

^a Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Cerebral cortex; Epigenetics; Gene expression; Histone acetylation; Neuronal differentiation; Progenitors

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; MESSENGER RNA; METASTASIS ASSOCIATED PROTEIN 2; PROTEIN NURD; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AT RICH SEQUENCE; BRAIN DEVELOPMENT; CHROMATIN; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE FUNCTION; NERVE CELL DIFFERENTIATION; NEWBORN; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; RNA STABILITY; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; BASE SEQUENCE; BRAIN; CEREBRAL CORTEX; CHROMATIN; DNA PRIMERS; EMBRYO, MAMMALIAN; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN D; HISTONE DEACETYLASES; IMMUNOPHENOTYPING; MOLECULAR SEQUENCE DATA; PREGNANCY; RATS; TRANSFECTION;

EID: 56449088387     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhn051     Document Type: Article

References (51)

1. Ahringer J. 2000. NuRD and SIN3 histone deacetylase complexes in development. Trends Genet. 16:351-356.
2. Alvarez JD, Yasui DH, Niida H, Joh T, Loh DY, Kohwi-Shigematsu T. 2000. The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Genes Dev. 14:521-535.
3. Ballas N, Mandel G. 2005. The many faces of REST oversee epigenetic programming of neuronal genes. Curr Opin Neurobiol. 15:500-506.
4. Berube NG, Mangelsdorf M, Jagla M, Vanderluit J, Garrick D, Gibbons RJ, Higgs DR, Slack RS, Picketts DJ. 2005. The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. J Clin Invest. 115:258-267.
5. Blaxall BC, Dwyer-Nield LD, Bauer AK, Bohlmeyer TJ, Malkinson AM, Port JD. 2000. Differential expression and localization of the mRNA binding proteins, AU-rich element mRNA binding protein (AUF1) and Hu antigen R (HuR), in neoplastic lung tissue. Mol Carcinog. 28:76-83.
6. Brenner RM, Slayden OD, Rodgers WH, Critchley HO, Carroll R, Nie XJ, Mah K. 2003. Immunocytochemical assessment of mitotic activity with an antibody to phosphorylated histone H3 in the macaque and human endometrium. Human reproduction. 18(6):1185-1193.
7. Britanova O, Akopov S, Lukyanov S, Gruss P, Tarabykin V. 2005. Novel transcription factor Satb2 interacts with matrix attachment region DNA elements in a tissue-spacific manner and demonstrates cell-type-dependent expression in the developing mouse CNS. Eur J Neurosci. 21:658-668.
8. Brewer G. 2002. Messenger RNA decay during aging and development. Ageing Res Rev. 1:607-625.
9. Bowen NJ, Fujita N, Kajita M, Wade PA. 2004. Mi-2/NuRD: multiple complexes for many purposes. Biochim Biophys Acta. 1677:52-57.
10. Cobos I, Calcagnotto ME, Vilaythong AJ, Thwin MT, Noebels JL, Baraban SC, Rubenstein JL. 2005. Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy. Nat Neurosci. 8:1059-1068.
11. Dempsey LA, Hanakahi LA, Maizels N. 1998. A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein. J Biol Chem. 273:29224-29229.
12. Dickinson LA, Joh T, Kohwi Y, Kohwi-Shigematsu T. 1992. A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition. Cell. 70:631-645.
13. Dickinson LA, Kohwi ST. 1995. Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential. Mol Cell Biol. 15:456-465.
14. Dobi A, Szemes M, Lee C, Palkovits M, Lim F, Gyorgy A, Mahan MA, Agoston DV. 2006. AUF1 is expressed in the developing brain, binds to AT-rich double-stranded DNA, and regulates enkephalin gene expression. J Biol Chem. 281:28889-28900.
15. Enokizono Y, Konishi Y, Nagata K, Ouhashi K, Uesugi S, Ishikawa F, Katahira M. 2005. Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by hnRNP D. J Biol Chem.
16. Eversole A, Maizels N. 2000. In vitro properties of the conserved mammalian protein hnRNP D suggest a role in telomere maintenance. Mol Cell Biol. 20:5425-5432.
17. Feng Q, Zhang Y. 2003. The NuRD complex: linking histone modification to nucleosome remodeling. Curr Top Microbiol Immunol. 274:269-290.
18. Guillemot F. 2005. Cellular and molecular control of neurogenesis in the mammalian tlencephalon. Curr Opin Cell Biol. 17:639-647.
19. Gyorgy AB, Szemes M, de Juan Romero C, Tarabykin V, Agoston DV. 2008. SATB2 interacts with chromatin-remodeling molecules in differentiating cortical neurons. Eur J Neurosci. 27:865-873.
20. Hsieh J, Gage FH. 2004. Epigenetic control of neural stem cell fate. Curr Opin Genet Dev. 14:461-469.
21. Hsieh J, Gage FH. 2005. Chromatin remodeling in neural development and plasticity. Curr Opin Cell Biol. 17:664-671.
22. Jaenisch R, Bird A. 2003. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet. 33(Suppl.):245-254.
23. Kageyama R, Ishibashi M, Takebayashi K, Tomita K. 1997. bHLH transcription factors and mammalian neuronal differentiation. Int J Biochem Cell Biol. 29:1389-1399.
24. Kim JH, Panchision D, Kittappa R, McKay R. 2003. Generating CNS neurons from embryonic, fetal, and adult stem cells. Methods Enzymol. 365:303-327.
25. Kumar NV, Bernstein LR. 2001. A new analytical scale DNA affinity binding assay for analyses of specific protein-DNA interactions. Anal Biochem. 299:203-210.
26. Laroia G, Schneider RJ. 2002. Alternate exon insertion controls selective ubiquitination and degradation of different AUF1 protein isoforms. Nucleic Acids Res. 30:3052-3058.
27. Lu JY, Sadri N, Schneider RJ. 2006. Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs. Genes Dev. 20:3174-3184.
28. Lu JY, Schneider RJ. 2004. Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay. J Biol Chem. 279:12974-12979.
29. Lunyak VV, Rosenfield MG. 2005. No rest for REST: REST/NRSF regulation of neurogenesis. Cell. 121:499-501.
30. Mal A, Sturniolo M, Schiltz RL, Ghosh MK, Harter ML. 2001. A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: inhibition of the myogenic program. Embo J. 20:1739-1753.
31. Maric D, Maric I, Chang YH, Barker JL. 2003. Prospective cell sorting of embryonic rat neural stem cells and neuronal and glial progenitors reveals selective effects of basic fibroblast growth factor and epidermal growth factor on self-renewal and differentiation. J Neurosci. 23:240-251.
32. McConnell SK. 1988. Fates of visual cortical neurons in the ferret after isochronic and heterochronic transplantation. J Neurosci. 8:945-974.
33. Ohnuma S, Harris WA. 2003. Neurogenesis and the cell cycle. Neuron. 40:199-208.
34. Pauli U, Chiu JF, Ditullio P, Kroeger P, Shalhoub V, Rowe T, Stein G, Stein J. 1989. Specific interactions of histone H1 and a 45 kilodalton nuclear protein with a putative matrix attachment site in the distal promoter region of a cell cycle-regulated human histone gene. J Cell Physiol. 139:320-328.
35. Rakic P. 2006. A century of progress in corticoneurogenesis: from silver impregnation to genetic engineering. Cereb Cortex. 16(Suppl. 1):i3-i17.
36. Rayzman VM, Sentry JW. 2006. MCA1 detection of histone H3 serine 10 phosphorylation, a noverl biomarker for determination of mitotic indices. Human antibodies. 15:71-80.
37. Recillas-Targa F, Razin SV. 2001. Chromatin domains and regulation of gene expression: familiar and enigmatic clusters of chicken globin genes. Crit Rev Eukaryot Gene Expr. 11:227-242.
38. Reeves R. 2000. Structure and function of the HMGI(Y) family of architectural transcription factors. Environ Health Perspect. 108:803-809.
39. Sarkar B, Xi Q, He C, Schneider RJ. 2003. Selective degradation of AU-rich mRNAs promoted by the p37 AUF1 protein isoform. Mol Cell Biol. 23:6685-6693.
40. Shen S, Li J, Casaccia-Bonnefil P. 2005. Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol. 169:577-589.
41. Sommer L, Ma Q, Anderson DJ. 1996. Neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol Cell Neurosci. 8:221-241.
42. Strahl-Bolsinger S, Hecht A, Luo K, Grunstein M. 1997. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11:83-93.
43. Szemes M, Gyorgy A, Paweletz C, Dobi A, Agoston DV. 2006. Isolation and characterization of SATB2, a novel AT-rich DNA binding protein expressed in development- and cell-specific manner in the rat brain. Neurochem Res. 31:643-655.
44. Tolnay M, Baranyi L, Tsokos GC. 2000. Heterogeneous nuclear ribonucleoprotein D0 contains transactivator and DNA-binding domains. Biochem J. 348(Pt 1):151-158.
45. Torrisani J, Unterberger A, Tendulkar SR, Shikimi K, Szyf M. 2007. AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability. Mol Cell Biol. 1:395-410.
46. Wagner BJ, DeMaria CT, Sun Y, Wilson GM, Brewer G. 1998. Structure and genomic organization of the human AUF1 gene: alternative pre-Mrna splicing generates four protein isoforms. Genomics. 48:195-202.
47. Woynarowski JM. 2004. AT islands - their nature and potential for anticancer strategies. Curr Cancer Drug Targets. 4:219-234.
48. Yao YL, Yang WM. 2003. The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity. J Biol Chem. 278:42560-42568.
49. Yasui D, Miyano M, Cai S, Varga-Weisz P, Kohwi-Shigematsu T. 2002. SATB1 targets chromatin remodelling to regulate genes over long distances. Nature. 419:641-645.
50. Zhang Y, Ng HH, Erdjument-Bromage H, Tempst P, Bird A, Reinberg D. 1999. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev. 13:1924-1935.
51. Zhang W, Wagner BJ, Ehrenman K, Schaefer AW, DeMaria CT, Crater D, DeHaven K, Long L, Brewer G. 1993. Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1. Mol Cell Biol. 13:7652-7665.