Treatment of merkel cell carcinoma

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 27, Issue 5, 2004, Pages 510-515

  Eng, Tony Y ^a,b   Boersma, Melisa G K ^a   Fuller, Clifton D ^a   Cavanaugh, Sean X ^a   Valenzuela, Fabio ^a   Herman, Terence S ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b BROOKE ARMY MEDICAL CENTER   (United States)

Author keywords

Chemotherapy; Merkel cell carcinoma; Neuroendocrine; Radiation therapy; Surgery

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DACARBAZINE; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUOROURACIL; METHOTREXATE; STREPTOZOCIN; VINCRISTINE;

ADULT; AGED; BEAM THERAPY; CANCER ADJUVANT THERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL PROTOCOL; EARLY DIAGNOSIS; EVALUATION; FEMALE; FOLLOW UP; HEAD AND NECK CANCER; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INOPERABLE CANCER; KAPLAN MEIER METHOD; LIMB AMPUTATION; LIMB TUMOR; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MERKEL CELL TUMOR; PROGNOSIS; RADIATION DOSE; RETROSPECTIVE STUDY; REVIEW; SEX DIFFERENCE; STATISTICAL ANALYSIS; SURVIVAL RATE; TRUNK; TUMOR BIOPSY; TUMOR VOLUME;

AGED; CARCINOMA, MERKEL CELL; COMBINED MODALITY THERAPY; FEMALE; HUMANS; MALE; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; RETROSPECTIVE STUDIES; SKIN NEOPLASMS; SURVIVAL ANALYSIS;

EID: 5644302932     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.coc.0000135567.62750.f4     Document Type: Review

References (46)

1. Toker C. Trabecular carcinoma of the skin. Arch Dermatol. 1972;105: 107-110.
2. Tang CK, Toker C. Trabecular carcinoma of the skin. An ultrastructural study. Cancer. 1978;42:2311-2321.
3. Kivela T, Tarkkanen A. The Merkel cell and associated neoplasm in the eyelids and periocular region. Surv Ophthalmol. 1990;35:171-187.
4. Rice RD, Chonkich GD, Thompson KS, et al. Merkel cell tumor of the head and neck: five new cases with literature review. Arch Otolaryngol Head Neck Surg. 1993;119:782-786.
5. Chuang TY, Su WPD, Muller SA. Incidence of cutaneous T cell lymphoma and other rare skin cancers in a defined population. J Am Acad Dermatol. 1990;23:254-256.
6. Hitchcock CL, Bland KI, Laney RG. Neuroendocrine (Merkel cell) carcinoma of the skin. Ann Surg. 1988;207:201.
7. Medina-Franco H, Urist MM, Fiveash J, et al. Multimodality treatment of Merkel cell carcinoma: case series and literature review of 1024 cases. Ann Surg Oncol. 2001;8:204-208.
8. Yiengpruksawan A, Coit DG, Thaler HT, et al. Merkel cell carcinoma: prognosis and management. Arch Surg. 1991;126:1514-1519.
9. Leonard JH, Ramsay JR, Kearsely JH, et al. Radiation sensitivity of Merkel cell carcinoma cell lines. Int J Radiat Oncol Biol Phys. 1995; 32:1401-1407.
10. Suntharalingam M, Rudoltz MS, Mendenhall WM, et al. Radiotherapy for Merkel cell carcinoma of the skin of the head and neck. Head Neck. 1995;17:96-101.
11. Meeuwissen JA, Bourne RG, Kearsley JH. The importance of postoperative radiation therapy in the treatment of Merkel cell carcinoma. Int J Radiat Oncol Biol Phys. 1995;31:325-331.
12. Ratner D, Nelson BR, Brown MD, et al. Merkel cell carcinoma. J Am Acad Dermatol. 1993;29:143-155.
13. Stawowy LM, Krull EA, Maeda K. Merkel cell carcinoma: a challenge. J Dermatol Surg Oncol. 1986;12:443-447.
14. Gu J, Polak JM, Van Noorden S, et al. Immunostaining of neuron-specific enolase as a diagnostic tool for Merkel cell carcinoma. Cancer. 1983;52:1039-1043.
15. Warner TF, Uno H, Hafez R, et al. Merkel cells and Merkel cell tumors: Ultrastructure, immunocytochemistry and review of the literature. Cancer. 1983;52:238-245.
16. Hauser H, Wolf G, Klimpfinger M. Neuroendocrine tumours in various organ systems in a ten-year period. Eur J Surg Oncol. 1995;211:297-300.
17. Haag ML, Glass LF, Fenske NA. Merkel cell carcinoma: diagnosis and treatment. Dermatol Surg. 1995;21:669-683.
18. Pitale M, Sessions RB, Husain S. An analysis of prognostic factors in cutaneous neuroendocrine carcinoma. Laryngoscope. 1992;102:244-249.
19. Shaw JHF, Rumball E. Merkel cell tumour: clinical behaviour and treatment. Br J Surg. 1991;78:138-142.
20. Goepfert H, Remmler De Silva E, Wheeler B. Merkel cell carcinoma (endocrine carcinoma of the skin) of the head and neck. Arch Otolaryngol. 1984;110:707-712.
21. Smith DE, Bielamowiczz S, Kagan AR, et al. Cutaneous neuroendocrine (Merkel cell) carcinoma: a report of 35 cases. Am J Clin Oncol. 1995;18:199-203.
22. Shack BR, Barton RM, DeLozier J, et al. Is aggressive surgical management justified in the treatment of Merkel cell carcinoma? Plast Reconstr Surg. 1994;9:970-975.
23. Tennvall J, Biorklund A, Johansson L, et al. Merkel cell carcinoma: management of primary, recurrent and metastatic disease. A clinicopathological study of 17 patients. Eur J Surg Oncol. 1989;15:1-9.
24. Bielamowicz S, Smith D, Abemayor E. Merkel cell carcinoma: an aggressive skin neoplasm. Laryngoscope. 1994;104:528-532.
25. Pacella J, Ashby M, Ainslie J, et al. The role of radiotherapy in the management of primary cutaneous neuroendocrine tumors (Merkel cell or trabecular carcinoma): experience at the Peter Maccallum Cancer Institute (Melbourne, Australia). Int J Radiat Oncol Biol Phys. 1988;14: 1077-1084.
26. Ashby MA, Jones DH, Tasker AD, et al. Primary cutaneous neuroendocrine (Merkel cell or trabecular carcinoma) tumours of the skin: a radioresponsive tumour. Clin Radiol. 1989;40:85-87.
27. Hasle H. Merkel cell carcinoma: the role of primary treatment with radiotherapy. Clin Oncol. 1991;3:114-116.
28. Westgate SJ. Radiation therapy for skin tumors. Facial Skin Malig II. 1993;26:295-309.
29. Bourne RG, O'Rourke MGE. Management of Merkel cell tumour. Aust N Z J Surg. 1988;58:971-974.
30. Morrison WH, Peters LJ, Silva EG, et al. The essential role of radiation therapy in securing locoregional control of Merkel cell carcinoma. Int J Radiat Oncol Biol Phys. 1990;19:583-591.
31. Wilder RB, Harari PM, Grahm AR, et al. Merkel cell carcinoma: improved-regional control with postoperative radiotherapy. Cancer. 1991;68:1004.
32. Collar AM, Gates JO, Gibbs FA. Merkel cell carcinoma: combined surgery and radiation therapy. Am Surg. 1986;52:159-164.
33. Ferrau F, Micali, Guitart J. Merkel cell carcinoma of the scalp: dramatic resolution with primary chemotherapy. J Am Acad Dermatol. 1994;31: 271-272.
34. Redmond J III, Perry J, Sowray P, et al. Chemotherapy of disseminated Merkel cell carcinoma. Am J Clin Oncol. 1991;14:305-307.
35. Fenig E, Lurie H, Sulkes A. The use of cyclophosphamide, methotrexate, and 5-fluorouracil in the treatment of Merkel cell carcinoma. Am J Clin Oncol. 1993;16:54-57.
36. Davis MP, Miller EM, Rau RC, et al. The use of VP16 and cisplatinum in the treatment of Merkel cell carcinoma. J Dermatol Surg Oncol. 1990;16:276-278.
37. Crown J, Lipzstein R, Cohen S, et al. Chemotherapy of metastatic Merkel cell cancer. Cancer Invest. 1991;9:129-132.
38. Pectasides D, Moutzourides G, Dimitriadis M, et al. Chemotherapy for Merkel cell carcinoma with carboplatinum and etoposide. Am J Clin Oncol. 1995;18:418-420.
39. Bartolomeo MD, Bajetta E, Bochicchio AM, et al. A phase II trial of dacarbazine, Fluorouracil and epirubicin in patients with neuroendocrine tumours. A study by the Italian trials in Medical Oncology Group. Ann Oncol. 1995;6:77-79.
40. Fenig E, Lurie H, Klien B, et al. The treatment of Advanced Merkel cell carcinoma. A multimodality chemotherapy and radiation therapy treatment approach. J Dermatol Surg Oncol. 1993;19:860-864.
41. Kearsley JH, Hurst T, Khoo SK. Chemosensitivity testing of primary cultures of Merkel cell cancer. Anticancer Drugs. 1993;4:571-575.
42. Tuneu A, Pujol RM, Barnadas MA, et al. Post irradiation Merkel cell carcinoma. J Am Acad Dermatol. 1989;20:505-507.
43. Duncan WC, Tschen JA. Spontaneous regression of Merkel cell (neuroendocrine) carcinoma of the skin. J Am Acad Dermatol. 1993;29:653-654.
44. O'Rourke MGE, Bell JR. Merkel cell tumor with spontaneous regression. J Dermatol Surg Oncol. 1986;12:994-997.
45. Kayashima K, Ono T, Johno M, et al. Spontaneous regression in Merkel cell (neuroendocrine) carcinoma of the skin. Arch Dermatol. 1991;127: 550-553.
46. Boyle F, Pendlebury S, Bell D. Further insight into the natural history and management of primary cutaneous neuroendocrine (Merkel cell) carcinoma. Int J Radiat Oncol Biol Phys. 1995;31:315-323.