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9). We have repeated the experiments with other substrates, such as those reported in Table 1, following the reported procedure and always no traces of nitriles were detected. We have no explanation for this disagreement: in our opinion, this might perhaps depend on the distillation procedure adopted from the above-cited authors that should have caused hydrochloride elimination from the substrate.
-
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25
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5644294432
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note
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The reaction is not chemoselective: a mixture of primary and secondary amines yielded a mixture of chloroamines when reacted with 1 equiv of TCCA.
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Probably owing to the formation of insoluble salts formed by TEA and the formed trihydroxytriazine.
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29
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5644298501
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note
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13C NMR: δ = 124.8, 27.1, 26.9, 17.4, 11.1.
-
-
-
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