New C(4)-functionalized colchicine derivatives by a versatile multicomponent electrophilic aromatic substitution

Helvetica Chimica Acta

Volumn 87, Issue 9, 2004, Pages 2266-2272

  Bensel, Nicolas ^a,c   Lagnoux, David ^a   Niggli, Verena ^a   Wartmann, Markus ^b   Reymond, Jean Louis ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Novalyst Discovery   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; AROMATIC COMPOUNDS; CARBOXYLIC ACIDS; DERIVATIVES; KETONES; SUBSTITUTION REACTIONS;

ANTIPROLIFERATIVE EFFECTS; COLCHICINE; NEUTROPHILS;

ALKYLATION;

ALDEHYDE; AMIDE; AROMATIC COMPOUND; CARBOXYLIC ACID DERIVATIVE; COLCHICINE; COLCHICINE DERIVATIVE; SULFURIC ACID;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL POLARITY; CELL PROLIFERATION; CHEMICAL STRUCTURE; ELECTRON; HUMAN; HUMAN CELL; MULTICOMPONENT ELECTROPHILIC AROMATIC SUBSTITUTION; NEUTROPHIL; PRIORITY JOURNAL; SUBSTITUTION REACTION;

EID: 5644300519     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200490203     Document Type: Article

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