Functional and histopathological study of the pancreas in hamsters (Mesocricetus auratus) infected and reinfected with Trypanosoma cruzi

Parasitology Research

Volumn 94, Issue 2, 2004, Pages 125-133

  Modesto Dos Santos, Vitorino ^a   Aurelho De Lima, Marcus ^a   Cabrine Santos, Marlene ^a   Marquez, Daniela De Stefani ^a   Pereira, Gilberto De Araújo ^a   Lages Silva, Eliane ^a   Ramírez, Luis Eduardo ^a  

^a FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; PANCREAS POLYPEPTIDE; PEROXIDASE; SOMATOSTATIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATROPHY; BLOOD CLOTTING TEST; CELL COUNT; CHAGAS DISEASE; CHRONIC GASTRITIS; CONTROLLED STUDY; FIBROSIS; GLUCOSE BLOOD LEVEL; HAMSTER; HEMATOCRIT; HYPOINSULINEMIA; INFLAMMATORY INFILTRATE; INSULIN BLOOD LEVEL; INSULITIS; MALE; NEURITIS; NONHUMAN; PANCREAS FUNCTION DISORDER; PANCREAS ISLET CELL; PANCREATITIS; PARASITOSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TRYPANOSOMA CRUZI;

ANIMALS; CHAGAS DISEASE; CRICETINAE; HUMANS; ISLETS OF LANGERHANS; MESOCRICETUS; PANCREAS; PANCREATITIS; TRYPANOSOMA CRUZI;

ANIMALIA; CRICETINAE; MESOCRICETUS; MESOCRICETUS AURATUS; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 5644291978     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00436-004-1183-8     Document Type: Article

References (36)

1. Ahrén B (2000) Autonomic regulation of islet hormone secretion - implications for health and disease. Diabetologia 43:393-410
2. Barbosa AJA, Gobbi H, Lino BT, Lages-Silva E, Ramírez LE, Teixeira VPA, Almeida HO (1986) A comparative study between haematoxilin and eosin and the peroxidase anti-peroxidase stains for tissular parasitism quantification in chronic chagasic cardiomyopathy. Rev Inst Med Trop Sao Paulo 28:91-96
3. Bice DE, Zeledon R (1970) Comparison of infectivity of strains of Trypanosoma cruzi (Chagas, 1909). J Parasitol 56:663-670
4. Brener Z, Ramirez LE (1985) Modelo crônico da doença de Chagas experimental. In: Cançado JR, Chuster M (Eds) Cardiopatia chagásica. Fundação Carlos Chagas, Belo Horizonte, pp 23-28
5. Cabrine-Santos M, Lages-Silva E, Chapadeiro E, Ramirez LE (2001) Trypanosoma cruzi: characterization of reinfection and search for tissue tropism in hamsters (Mesocricetus auratus). Exp Parasitol 99:160-167
6. Cabrine-Santos M, Santos VM, Lima MA, Abreu MEA, Lages-Silva E, Ramirez LE (2003) Genitourinary changes in hamsters infected and reinfected with Trypanosoma cruzi. Mem Inst Oswaldo Cruz 98:523-528
7. Chapadeiro E, Florêncio RFC, Afonso PC, Beraldo PSS, De Jesus PC, Junqueira Junior LF (1991) Neuronal counting and parasympathetic dysfunction in the hearts of chronically Trypanosoma cruzi infected rats. Rev Inst Med Trop Sao Paulo 33:337-341
8. Chiari E, Dias JCP, Lana M, Chiari CA (1989) Hemocultures for the parasitological diagnosis of human chronic chagasic disease. Rev Soc Bras Med Trop 22:19-22
9. Clark IA, Al Yaman FM, Jacobson LS (1997) The biological basis of malarial disease. Int J Parasitol 27:1237-1249
10. Galassetti P, Davis SN (2000) Effects of insulin per se on neuroendocrine and metabolic counter-regulatory responses to hypoglicemia. Clin Sci 99:351-362
11. Garcia-Ocaña A, Takane KK, Syed MA, Philbrick WM, Vasavada RC, Stewart AS (2000) Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia. J Biol Chem 275:1226-1232
12. Gomes YM (1997) PCR and serodiagnosis of chronic Chagas' disease: biotechnological advances. Appl Biochem Biotechnol 66:107-109
13. Higuchi ML, De Brito T, Reis M (1993) Correlation between Trypanosoma cruzi parasitism and myocardial inflammatory infiltrate in human chronic chagasic myocarditis: light microscopy and immunohistochemical findings. Cardiovasc Pathol 2:101-106
14. Hsu SM, Raine L, Fanger H (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase technics: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29:577-580
15. Köberle F (1968) Chagas' disease and Chagas' syndromes: the pathology of American trypanosomiasis. Adv Parasitol 6:63-116
16. Konishi N, Ward JM, Waalkes MP (1990) Pancreatic hepatocytes in Fischer and Wistar rats induced by repeated injections of cadmium chloride. Toxicol Appl Pharmacol 104:149-156
17. Lages-Silva E, Crema E, Ramirez LE, Macedo AM, Pena SD, Chiari E (2001) Relationship between Trypanosoma cruzi and human chagasic megaesophagus: blood and tissue parasitism. Am J Trop Med Hyg 65:435-441
18. Luquetti AO, Rassi A (2000) Diagnóstico laboratorial da infecção pelo Trypanosoma cruzi. In: Brener Z, Andrade ZA, Barral-Netto M (Eds.) Trypanosoma cruzi e doença de Chagas. Guanabara Koogan, Rio de Janeiro, pp 344-378
19. (1996) Revised guide for the care and use of laboratory animals. (NIH guides, vol 25) National Academy, Washington, D.C.
20. Prata A (2001) Clinical and epidemiological aspects of Chagas disease. Lancet 1:92-100
21. Prata JA, Praia Júnior JA, Castro CN, Macedo V, Prata A (1995) Anisocoria na fase crônica da doença de Chagas. Rev Soc Bras Med Trop 28:131-133
22. Ramírez LE, Lages-Silva E, Soares-Junior JM, Chapadeiro E (1994) The hamster (Mesocricetus auratus) as experimental model in Chagas' disease: parasitological and histopathological studies in acute and chronic phases of Trypanosoma cruzi infection. Rev Soc Bras Med Trop 27:163-169
23. Rocha A, Almeida HO, Teixeira VPA, Silva AM (1985) Prevalência da colelitíase em chagásicos crônicos necropsiados no Triângulo Mineiro - correlação com o megaesôfago, o megacólon e a insuficiência cardíaca. Arq Gastroenterol 22:3-6
24. Rocha A, Oliveira LCM, Alves RS, Lopes ER (1998) Despopulaçã o neuronal pancreática em chagásicos crônicos. Rev Soc Bras Med Trop 31:43-49
25. Rossi MA, Ramos SG (1996) Pathogenesis of chronic Chagas' myocarditis: an overview. Cardiovasc Pathol 5:197-202
26. Saho S, Kadota Y, Sameshima T, Miyao J, Tsurumaru T, Yoshimura N (1997) The effects of sevoflurane anesthesia on insulin secretion and glucose metabolism in pigs. Anesth Analg 84:1359-1365
27. Saldanha JC, Santos VM, Reis MA, Cunha DF, Teixeira VPA (2001) Morphologic and morphometric evaluation of pancreatic islets in chronic Chagas' disease. Rev Hosp Clin Fac Med Sao Paulo 56:131-138
28. Santos VM, Teixeira VPA, Cunha DF, Cunha SFC, Monteiro JP, Santos JAM, Santos TAM, Santos LAM (1999a) Pancreatic anatomopathology changes in chronic chagasic women. Preliminary data. Arq Gastroenterol 36:127-132
29. Santos VM, Cunha SFC, Teixeira VPA, Monteiro JP, Santos JAM, Santos TAM, Santos LAM, Cunha DF (1999b) Freqüência de diabetes mellitus e hiperglicemia em mulheres chagásicas e não-chagásicas. Rev Soc Bras Med Trop 32:489-496
30. Santos VM, Lima MA, Cabrine-Santos M, Márquez DE, Reis MG, Pereira GA, Lages-Silva E, Ramírez LE (2002) Pancreatic hepatocytes in hamsters (Mesocricetus auratus) infected with Trypanosoma cruzi. Exp Parasitol 100:103-111
31. Tarleton RL (2001) Parasite persistence in aetiology of Chagas' disease. Int J Parasitol 31:550-554
32. Tiscornia MO, Lehmann E, De Hamamura SS, Negri G, Otero G, Waisman H (2000) Sistema nervioso autónome y páncreas. (Análisis de la influencia de diversos tipos de denervación autonómica en los fenómenos de regeneración glandular y en las de las interacciones del eje endocrino-exocrino). Acta Gastroenterol Latinoam 30:253-265
33. Titus RG, Sherry B, Cerami A (1992) The involvement of TNF, IL-1 and IFL-6 in the immune response to protozoan parasites. Immunol Today 12:A13-A28
34. Troncon LEA, Barbosa AJA, Carvalhais JN, Romanello LMF (1996) Lower density of antral somatostatin-immunoreactive cells in the digestive form of chronic Chagas' disease. Braz J Med Biol Res 29:1449-1454
35. Watkins R (1966) Comparison of infections produced by two strains of Trypanosoma cruzi in mice. J Parasitol 52:958-961
36. Woo PTK (1971) Evaluation of the hematocrite centrifuge and other technics for the field diagnosis of human trypanosomiasis and filariasis. Acta Trop 28:298-303