Functional and genetic assessment of IFN-γ receptor in patients with clinical tuberculosis

International Journal of Tuberculosis and Lung Disease

Volumn 8, Issue 10, 2004, Pages 1221-1227

  Park, Gye Young ^a   Im, Y H ^a   Ahn, C H ^a   Park, J W ^a   Jeong, S W ^a   Ahn, J Y ^a   Hwang, Y J ^a  

^a Gachon University College of Medicine   (South Korea)

Author keywords

CD64; HLA DR; IFN ; IFN receptor; TNF ; Tuberculosis

Indexed keywords

CD64 ANTIGEN; GAMMA INTERFERON RECEPTOR; HLA DR ANTIGEN; LIPOPOLYSACCHARIDE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC DISORDER; GENETIC SUSCEPTIBILITY; HUMAN; INFECTION SENSITIVITY; MILIARY TUBERCULOSIS; MUTATIONAL ANALYSIS; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; STAT1 GENE; TUBERCULOSIS;

ADULT; CASE-CONTROL STUDIES; DISEASE SUSCEPTIBILITY; DNA-BINDING PROTEINS; HLA-DR ANTIGENS; HUMANS; LIPOPOLYSACCHARIDES; MONOCYTES; RECEPTORS, IGG; RECEPTORS, INTERFERON; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TUBERCULOSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 5644262529     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Espinal M A, Kim S J, Suarez P G, et al. Standard short-course chemotherapy for drug-resistant tuberculosis; treatment outcomes in 6 countries. JAMA 2000; 83: 2537-2545.
2. Orme I M, Roberts A D, Griffin J P, Abrams J S. Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection. J Immunol 1993; 151: 518-525.
3. Flynn J L, Chan J, Triebold K J, Dalton D K, Stewart T A, Bloom B R. An essential role for interferon-gamma in resistance to Mycobacterium tuberculosis infection. J Exp Med 1993; 178: 2249-2254.
4. Schraufnagel D E. Tuberculosis treatment for the beginning of the next century. Int J Tuberc Lung Dis 1999; 3: 651-652.
5. Toossi Z. Adjunctive immunotherapy of tuberculosis. Cytokines Cell Mol Ther 1998; 4: 105-112.
6. Holland S M. Immunotherapy of mycobacterial infection. Seminars in Respiratory Infections 2001; 16: 47-59.
7. Newport M J, Huxley C M, Huston S, et al. A mutation in the interferon-gamma receptor gene and susceptibility to mycobacterial infection. N Engl J Med 1996; 335: 1941-1949.
8. Jouanguy E, Altare F, Lamhamedi S, et al. IFN-γ receptor deficiency in an infant with fatal Bacille Calmette-Guerin infection. N Engl J Med 1996; 335: 1956-1962.
9. Levin M, Newport M J, D'Souza S, et al. Familial disseminated atypical mycobacterial infection in childhood: a human mycobacterial susceptibility gene. Lancet 1995; 345: 79-83.
10. Jouanguy E, Altare F, Lamhamedi S, et al. Interferon-gamma receptor deficiency in an infant with fatal BCG infection. N Engl J Med 1996; 335: 1956-1961.
11. Doffinger R, Jouanguy E, Dupuis S, Fondaneche M C, Casanova J. Partial interferon-gamma receptor signaling chain deficiency in a patient with BCG and Mycobacterium abscessus infection. J Infect Dis 2000; 181: 379-384.
12. Jouanguy E, Lambamedi S, Altare F, et al. Partial interferon-gamma receptor 1 deficiency in a child with tuberculosis BCG infection and a sibling with clinical tuberculosis. J Clin Invest 1997; 100: 2658-2664.
13. Sasaki Y, Nomura A, Kusuhara K, et al. Genetic basis of patients with BCG osteomyelitis in Japan: identification of dominant partial interferon-gamma receptor 1 deficiency as a predominant type. J Infect Dis 2002; 185; 706-709.
14. Jouanguy E, Dupuis S, Pallier A, et al. In a novel form of IFN-γR1 deficiency, cell surface receptors fail to bind IFN-γ. J Clin Invest 2000; 105: 1429-1436.
15. Jouanguy E, Lamhamedi-Cherradi S, Lammas D, et al. A human IFN-γR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection. Nat Genet 1999; 21: 370-378.
16. Holland S M, Dorman S E, Kwon A, et al. Abnormal regulation of IFN-γ IF-12, and TNF-α in human IFN-γ receptor 1 deficiency. J Infect Dis 1998; 178: 1095-1104.
17. Dorman S E, Holland S M. Mutation in the signal-transducing chain of the IFN-γ receptor and susceptibility to mycobacterial infection. J Clin Invest 1998; 101: 2364-2369.
18. Casanova J L, Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol 2002; 20: 581-620.
19. Dupuis S, Dargemont C, Fieschi C, et al. Impairment of mycobacterial but not viral immunity by a germline human STAT1 mutation. Science 2001; 293: 300-303.
20. Nathan C F. Neutrophil activation on biological surfaces: massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes. J Clin Invest 1987; 80: 1550-1557.
21. Celada A, Allen R, Esparza I, Gray P W, Schreiber R D. Demonstration and partial characterization of the interferon-gamma receptor on human monoclonal phagocytes. J Clin Invest 1985; 76: 2196-2205.
22. Otten L A, Steimle V. Quantitative control of MHC class II expression by the transactivator CIITA. Eur J Immunol 1998; 28: 473-478.
23. Schiff D E, Rae J, Martin T R, Davis B H, Curnutte J T. Increased phagocyte FcγR1 expression and improved Fcγ-receptor-mediated phagocytosis after in vivo recombinant human IFN-γ treatment of normal human subjects. Blood 1997; 90: 3187-3195.
24. Abbas A K, Lichtman A H, Pober J S. Cellular and molecular immunology. 4th ed. Philadelphia, PA: WB Saunders, 2000: pp 235-267.
25. Keane J, Pharm S G, Wise R P, et al. Tuberculosis associated with Infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med 2001; 345: 1098-1104.
26. Ting L M, Kim A C, Cattamanchi A, Ernst J D. Mycobacterium tuberculosis inhibits IFN-γ transcriptional responses without inhibiting activation of STAT1. J Immunol 1999; 163: 3898-3806.
27. Condos R, Raju B, Canova A, et al. Recombinant IFN-γ stimulates signal transduction and gene expression in alveolar macrophages in vitro and in tuberculosis patients. Infect Immun 2003; 71: 2058-2064.
28. Sugawara I, Yamada H, Kazumi Y, et al. Induction of granulomas in IFN-γ gene-disrupted mice by avirulent but not by virulent strains of Mycobacterium tuberculosis. J Med Microbiol 1998; 47: 871-877.