A fatal overdose of the ergot derivative cabergoline

Forensic Science International

Volumn 146, Issue 1, 2004, Pages 47-51

  Johansen, S S ^a   Karkov, J ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Cabergoline; Fatality; Poisoning; Whole blood

Indexed keywords

BUPRENORPHINE; CABERGOLINE; CODEINE; ERGOT DERIVATIVE; NARCOTIC AGENT; PARACETAMOL; PROPRANOLOL;

AGED; ARTICLE; AUTOPSY; BILE DUCT CARCINOMA; CASE REPORT; CONCENTRATION (PARAMETERS); CONFUSION; DEATH; DRUG BLOOD LEVEL; DRUG OVERDOSE; FEMALE; GALLBLADDER; HOSPITAL ADMISSION; HOSPITAL BED; HUMAN; JAUNDICE; LIVER; LIVER METASTASIS; LYMPH NODE; METASTASIS; MUSCLE WEAKNESS; PARKINSON DISEASE; PRIORITY JOURNAL;

EID: 5644262471     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2004.03.013     Document Type: Article

References (14)

1. Rinne U.K., Bracco F., Chouza C., Dupont E., Gershanik O., Marti Masso J.F., Montastruc J.L., Marsden C.D. PKDS009 study group. Drugs. 55(Suppl. 1):1998;23-30
2. Fariello R.G. Pharmacodynamic and pharmacokinetic features of cabergoline. Drugs. 55(Suppl. 1):1998;10-16
3. Lera G., Vaamode J., Rodriguez M., Obeso J.A. Cabergoline in Parkinsons's disease: long-term follow-up. Neurology. 43:1993;2587-2590
4. Persiani S., Rocchetti M., Pacciarini M.A., Holt B., Toon S., Strolin-Benedetti M. The effect of food on cabergoline pharmacokinetics and tolerability in healthy volunteers. Biopharm. Drug Dispos. 17:1996;443-455
5. M.S. Benedetti, E. Pianezzola, S. Persiani, R. Grimaldi, J.A. Obeso, Evaluation of the linearity of cabergoline pharmacokinitics in parkinsonian patients, in: 10th International symposium on Parkinson's disease, Tokyo, 27-30 October 1991.
6. Persiani S., Pianezzola E., Broutin F., Fonte G., Benedetti M.S. Radioimmunoassay for the synthetic ergoline derivative cabergoline in biological fluids. J. Immunoassay. 13:1992;457-476
7. Persiani S., Sassolas G., Piscitelli G., Bizollon C.A., Poggesi I., Pianezzola E., Edwards D.M.F., Benedetti M.S. Pharmacodynamics and relative bioavailability of cabergoline tablets versus solution in healthy volunteers. J. Pharma. Sci. 83(10):1994;1421-1424
8. Pianezzola E., Bellotti V., La Croix R., Benedetti M.S. Determination of cabergoline in plasma and urine by high-performance liquid chromatography with electrochemical detection. J. Chromatogr. 574:1992;170-174
9. Allievi C., Dostert P. Quantitative determination of cabergoline in human plasma using liquid chromatography combined with tandem mass spectrometry. Rapid Commun. Mass Spectrom. 12:1998;33-39
10. Igarashi K., Hotta K., Kasuya F., Abe K., Sakoda S. Determination of cabergoline and l-dopa in human plasma using liquid chromatography-tandem mass spectrometry. J. Chromatogr. B. 792:2003;55-61
11. Johansen S.S., Hansen A.C., Müller I.B., Lundemose J.B., Franzmann M. Three fatal cases of PMA and PMMA poisoning in Denmark. J. Anal. Tox. 27:2003;253-256
12. Johansen S.S., Genner J. A fatal case of amlodipine poisoning. J. Clin. Foren. Med. 10:2003;169-172
13. S. Felby, E. Nielsen. Den retskemiske blodalkoholbestemmelse ved København Universitets Retskemiske Institut (in Danish). Ugeskrift for Retsvæsen, 1990, pp. 260-264.
14. Christensen J., Dupont E., Østergaard K. Cabergoline plasma concentration is increased during concomitant treatment with itraconazole. Mov. Disord. 17:2002;1360-1395