A new HMG-CoA reductase inhibitor, pitavastatin remarkably retards the progression of high cholesterol induced atherosclerosis in rabbits

Atherosclerosis

Volumn 176, Issue 2, 2004, Pages 255-263

  Hayashi, Toshio ^a   Rani P, Juliet Arockia ^a   Fukatsu, Akiko ^a   Matsui Hirai, Hisako ^a   Osawa, Masako ^a   Miyazaki, Asaka ^a   Tsunekawa, Taku ^a   Kano Hayashi, Hatsuyo ^a   Iguchi, Akihisa ^a   Sumi, Daigo ^b   Ignarro, Louis J ^b  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Atherosclerosis; e NOS; endothelial nitric oxide synthase; Endothelial nitric oxide synthase; HMG CoA reductase inhibitor; nitric oxide; Nitric oxide; nitric oxide synthase; NO; NOS; ONOO ; peroxynitrite; Superoxide anion

Indexed keywords

3 NITROTYROSINE; ACETYLCHOLINE; CALCIMYCIN; CHOLESTEROL; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELATINASE A; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERSTITIAL COLLAGENASE; N(G) METHYLARGININE; PITAVASTATIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ARCH; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; DRUG SCREENING; ENZYME INHIBITION; FEMALE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; THORACIC AORTA; UPREGULATION;

ADMINISTRATION, ORAL; ANIMALS; ARTERIOSCLEROSIS; BIOLOGICAL AVAILABILITY; CHOLESTEROL, HDL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENZYME INHIBITORS; FEMALE; NITRIC OXIDE; QUINOLINES; RABBITS; TRIGLYCERIDES; UP-REGULATION;

EID: 5644259788     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2003.12.034     Document Type: Article

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