Preparation of new N-heterocyclic carbene metal-alkyne complexes and application to a stereocontrolled Pauson-Khand reaction

Synlett

Volumn , Issue 12, 2004, Pages 2103-2106

  Poulton, Andrew M ^a   Christie, Steven D R ^a   Fryatt, Ross ^a   Dale, Sophie H ^a   Elsegood, Mark R J ^a   Andrews, David M ^b,c  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Alkyne compexes; Asymmetric synthesis; Carbene complexes

Indexed keywords

ALKYNE; CARBENE; HETEROCYCLIC COMPOUND; METAL COMPLEX;

ARTICLE; ASYMMETRIC SYNTHESIS; COMPLEX FORMATION; PAUSON KHAND REACTION; REACTION ANALYSIS; STEREOCHEMISTRY; SYNTHESIS;

EID: 5644254686     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-831304     Document Type: Article

References (22)

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20. Determination of the absolute stereochemistry of the IPr substituted complexes and the cyclopentenones is under investigation and will be reported in due course.
21. We thank the referees for their suggestions for the mechanism of the epimerisation.
22. 2 core of the molecule was modelled as disordered with the Co atoms having minor disorder components with an occupancy factor of 8.4(2)%. Crystallographic data have been deposited with the Cambridge Crystallographic Data Centre (CCDC 229596).