Effects of aminoguanidine and antioxidant erdosteine on bleomycin-induced lung fibrosis in rats

Nitric Oxide - Biology and Chemistry

Volumn 11, Issue 2, 2004, Pages 156-165

  Yildirim, Zeki ^a   Turkoz, Yusuf ^a   Kotuk, Mahir ^a   Armutcu, Ferah ^b   Gurel, Ahmet ^b   Iraz, Mustafa ^a   Ozen, Suleyman ^c   Aydogdu, Ismet ^a   Akyol, Omer ^a  

^a INONU UNIVERSITY   (Turkey)

^b ZONGULDAK KARAELMAS UNIVERSITY   (Turkey)

^c YUZUNCU YIL UNIVERSITY   (Turkey)

Author keywords

Aminoguanidin; Bleomycin; Erdosteine; Lung fibrosis; Nitric oxide

Indexed keywords

AMINOGUANIDINE; ANTIBODY; BLEOMYCIN; ERDOSTEINE; GLUTATHIONE PEROXIDASE; HYDROXYPROLINE; MALONALDEHYDE; MYELOPEROXIDASE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HISTOLOGY; LUNG FIBROSIS; LUNG PARENCHYMA; MALE; NITRATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; STAINING;

ANIMALS; ANTIOXIDANTS; BLEOMYCIN; DRUG THERAPY, COMBINATION; GLUTATHIONE PEROXIDASE; GUANIDINES; MALE; MALONDIALDEHYDE; NITRIC OXIDE; PEROXIDASE; PULMONARY FIBROSIS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; THIOGLYCOLATES; THIOPHENES; TYROSINE;

ANIMALIA;

EID: 5644232445     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2004.07.011     Document Type: Article

References (40)

1. T.J. Gross, and G.W. Hunninghake Idiopathic pulmonary fibrosis N. Engl. J. Med. 345 16 2001 517 525
2. J.C. Weissler Idiopathic pulmonary fibrosis: cellular and molecular pathogenesis Am. J. Med. Sci. 297 1989 92 104
3. P.R. Eynott, D.A. Groneberg, G. Caramori, I.M. Adcock, L.E. Donnelly, S. Kharitonov, P.J. Barnes, and K.F. Chung Role of nitric oxide in allergic inflammation and bronchial hyperresponsiveness Eur. J. Pharmacol. 452 2002 123 133
4. P. Paredi, S.A. Kharitonov, and P.J. Barnes Analysis of expired air for oxidation products Am. J. Respir. Crit. Care Med. 166 2002 S31 S37
5. S.A. Kharitonov, F. Gonio, C. Kelly, S. Meah, and P.J. Barnes Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children Eur. Respir. J. 21 2003 433 438
6. P. Paredi, S.A. Kharitonov, S. Loukides, P. Pantelidis, R.M. du Bois, and P.J. Barnes Exhaled nitric oxide is increased in active fibrosing alveolitis Chest 115 1999 1352 1356
7. S.A. Kharitonov, A.U. Wells, B.J. O'Connor, P.J. Cole, D.M. Hansell, R.B. Logan-Sinclair, and P.J. Barnes Elevated levels of exhaled nitric oxide in bronchiectasis Am. J. Respir. Crit. Care Med. 151 1995 1889 1893
8. I.Y. Haddad, A. Panoskaltsis-Mortari, D.H. Ingbar, S. Yang, C.E. Milla, and B.R. Blazar High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation Am. J. Respir. Cell Mol. Biol. 20 1999 1125 1135
9. W.J. Caspary, D.A. Lanzo, and C. Niziak Effect of deoxyribonucleic acid on the production of reduced oxygen by bleomycin and iron Biochemistry 21 1982 334 338
10. D. Saleh, P.J. Barnes, and A. Giaid Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis Am. J. Respir. Crit Care Med. 155 1997 1763 1769
11. G. Gurujeyalakshmi, Y. Wang, and S.N. Giri Suppression of bleomycin-induced nitric oxide production in mice by taurine and niacin Nitric Oxide 4 2000 399 411
12. T.P. Misko, W.M. Moore, T.P. Kasten, G.A. Nickols, J.A. Corbett, R.G. Tilton, M.L. McDaniel, J.R. Williamson, and M.G. Currie Selective inhibition of the inducible nitric oxide synthase by aminoguanidine Eur. J. Pharmacol. 233 1993 119 125
13. S.N. Giri, I. Biring, T. Nguyen, Q. Wang, and D.M. Hyde Abrogation of bleomycin-induced lung fibrosis by nitric oxide synthase inhibitor, aminoguanidine in mice Nitric Oxide 7 2002 109 118
14. X.L. Chen, W.B. Li, A.M. Zhou, J. Ai, and S.S. Huang Role of endogenous peroxynitrite in pulmonary injury and fibrosis induced by bleomycin A5 in rats Acta Pharmacol. Sin. 24 2003 697 702
15. H. Ozyurt, S. Sogut, Z. Yildirim, L. Kart, M. Iraz, F. Armutcu, I. Temel, S. Ozen, A. Uzun, and O. Akyol Inhibitory effect of caffeic acid phenethyl ester on bleomycine-induced lung fibrosis in rats Clin. Chim. Acta 339 2004 65 75
16. T. Hoshino, H. Nakamura, M. Okamoto, S. Kato, S. Araya, K. Nomiyama, K. Oizumi, H.A. Young, H. Aizawa, and J. Yodoi Redox-active protein thioredoxin prevents proinflammatory cytokine- or bleomycin-induced lung injury Am. J. Respir. Crit. Care Med. 168 2003 1075 1083
17. S. Sogut, H. Ozyurt, F. Armutcu, L. Kart, M. Iraz, O. Akyol, S. Ozen, S. Kaplan, I. Temel, and Z. Yildirim Erdosteine prevents bleomycin-induced pulmonary fibrosis in rats Eur. J. Pharamocol. 494 2004 213 220
18. A. Serrano-Mollar, D. Closa, N. Prats, S. Blesa, M. Martinez-Losa, J. Cortijo, J.M. Estrela, E.J. Morcillo, and O. Bulbena In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats Br. J. Pharmacol. 138 2003 1037 1048
19. T. Ashcroft, J.M. Simpson, and V. Timbrell Simple method of estimating severity of pulmonary fibrosis on a numerical scale J. Clin. Pathol. 41 1988 467 470
20. Y. Sun, L.W. Oberley, and Y. Li A simple method for clinical assay of superoxide dismutase Clin. Chem. 34 1988 497 500
21. D.E. Pagia, and W.N. Valentine Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase J. Lab. Clin. Med. 70 1967 158 170
22. N.K. Cortas, and N.W. Wakid Determination of inorganic nitrate in serum and urine by a kinetic cadmium-reduction method Clin. Chem. 36 1990 1440 1443
23. W. Wasowicz, J. Neve, and A. Peretz Optimized steps in fluorometric determination of thiobarbituric acid-reactive substances in serum: Importance of extraction pH and influence of sample preservation and storage Clin. Chem. 39 1993 2522 2526
24. H. Wei, and K. Frenkel Relationship of oxidative events and DNA oxidation in SENCAR mice to in vivo promoting activity of phorbol ester-type tumor promoters Carcinogenesis 14 1993 1195 1201
25. J.B. Woessner The determination of hidroxyproline in tissue and protein samples containing small proportions of this amino acid Arch. Biochem. Biophys. 93 1961 440 447
26. H. Ischiropoulos, L. Zhu, and J.S. Beckman Peroxynitrite formation from macrophage-derived nitric oxide Arch. Biochem. Biophys. 298 1992 446 451
27. N.W. Kooy, J.A. Royall, Y.Z. Ye, D.R. Kelly, and J.S. Beckman Evidence for in vivo peroxynitrite production in human acute lung injury Am. J. Respir. Crit. Care Med. 151 1995 1250 1254
28. I.Y. Haddad, G. Pataki, P. Hu, C. Galliani, J.S. Beckman, and S. Matalon Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury J. Clin. Invest. 94 1994 2407 2413
29. A.J. Gow, D. Duran, S. Malcolm, and H. Ischiropoulos Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation FEBS Lett. 385 1996 63 66
30. J.S. Beckman Oxidative damage and tyrosine nitration from peroxynitrite Chem. Res. Toxicol. 9 1996 836 844
31. J.P. Eiserich, M. Hristova, C.E. Cross, A.D. Jones, B.A. Freeman, B. Halliwell, and A. van der Vliet Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils Nature 391 1998 393 397
32. W. Wu, Y. Chen, and S.L. Hazen Eosinophil peroxidase nitrates protein tyrosyl residues. Implications for oxidative damage by nitrating intermediates in eosinophilic inflammatory disorders J. Biol. Chem. 274 1999 25933 25944
33. M. Dorger, A.M. Allmeling, R. Kiefmann, A. Schropp, and F. Krombach Dual role of inducible nitric oxide synthase in acute asbestos-induced lung injury Free Radic. Biol. Med. 33 2002 491 501
34. X.L. Chen, S.S. Huang, W.B. Li, D.H. Wang, and X.L. Wang Inhibitory effect of aminoguanidine on bleomycin-induced pulmonary toxicity in rat Acta Pharmacol. Sin. 22 2001 711 715
35. S.H. Ihm, H.J. Yoo, S.W. Park, and J. Ihm Effect of aminoguanidine on lipid peroxidation in streptozotocin-induced diabetic rats Metabolism 48 1999 1141 1145
36. S. Sleijfer Bleomycin-induced pneumonitis Chest 120 2001 617 624
37. M. Denis Antioxidant therapy partially blocks immune induced lung fibrosis Inflammation 333 1995 207 219
38. Z. Yildirim, S. Sogut, E. Odaci, M. Iraz, H. Ozyurt, M. Kotuk, and O. Akyol Oral erdosteine administration attenuates cisplatin-induced renal tubular damage in rats Pharmacol. Res. 47 2003 149 156
39. E. Fadillioglu, H. Erdogan, S. Sogut, and I. Kuku Protective effects of erdosteine against doxorubicin-induced cardiomyopathy in rats J. Appl. Toxicol. 23 2003 71 74
40. W.A. Pryor, and G.L. Squadrito The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide Am. J. Physiol. 268 1995 699 722