Stereospecific synthesis of carbanucleotides designed for antisense methodology

Helvetica Chimica Acta

Volumn 87, Issue 9, 2004, Pages 2245-2265

  Zhu, Xue Feng ^a,b   Nydegger, Freddy ^a   Gossauer, Albert ^a  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULES; POLYMERS; STEREOCHEMISTRY; STRUCTURE (COMPOSITION);

CARBANUCLEOTIDES; OLIGONUCLEOTIDES;

SYNTHESIS (CHEMICAL);

2' DEOXYNUCLEOSIDE; 8,9,10 TRINORBOR 5 EN 2 ONE; ANTISENSE OLIGODEOXYNUCLEOTIDE; BORNANE DERIVATIVE; CARBANUCLEOTIDE; FUNCTIONAL GROUP; METHYL 2 [2 [[(TERT BUTYL)DIPHENYLSILYL]OXY]ETHYL] 4 (1,2,3,4 TETRAHYDRO 5 METHYL 2,4 DIOXOPYRIMIDIN 1 YL)CYCLOPENTANE ACETATE; METHYL 2 [[[(TERT BUTYL)DIPHENYLSILYL]OXY]METHYL] 4 (1,2,3,4 TETRAHYDRO 5 METHYL 2,4 DIOXOPYRAMIDIN 1 YL)CYCLOPENTANE ACETATE; METHYL 4 (6 AMINO 9H PURIN 9 YL) 2 [2 [[(TERT BUTYL)DIPHENYLSILYL]OXY]ETHYL]CYCLOPENTANE ACETATE; METHYL 4 (6 AMINO 9H PURIN 9 YL) 2 [[[(TERT BUTYL)DIPHENYLSILYL]OXY]METHYL]CYCLOOPENTANE ACETATE; NUCLEOTIDE DERIVATIVE; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; OPTICAL ROTATION; POLYMERIZATION; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOSPECIFICITY; SYNTHESIS;

EID: 5644223197     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200490202     Document Type: Article

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