Aligned PLGA/HA nanofibrous nanocomposite scaffolds for bone tissue engineering

Acta Biomaterialia

Volumn 5, Issue 1, 2009, Pages 305-315

  Jose, Moncy V ^a   Thomas, Vinoy ^b   Johnson, Kalonda T ^c   Dean, Derrick R ^a   Nyairo, Elijah ^d  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c and Radiation Oncology   (United States)

^d ALABAMA STATE UNIVERSITY   (United States)

Author keywords

Electrospinning; Nano hydroxyapatite; Nanocomposite; Poly (d,l lactide co glycolide)

Indexed keywords

BONE; ELASTIC MODULI; ELECTROSPINNING; GLASS; GLASS TRANSITION; HYDROXYAPATITE; NANOFIBERS; SCAFFOLDS (BIOLOGY); SCANNING ELECTRON MICROSCOPY; TEMPERATURE;

BONE TISSUE ENGINEERING; GLASS TRANSITION TEMPERATURE TG; GLYCOLIDE; L-LACTIDE; NANO-FIBROUS; NANO-HYDROXYAPATITE; NANOCOMPOSITE SCAFFOLDS; NANOFIBROUS SCAFFOLDS; PLGA/HA; POLY (D,L-LACTIDE-CO-GLYCOLIDE);

NANOCOMPOSITES;

GLASS; HYDROXYAPATITE; MOLECULAR SCAFFOLD; NANOCOMPOSITE; PHOSPHATE BUFFERED SALINE; POLYGLACTIN;

ARTICLE; BONE TISSUE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEGRADATION; HYDROPHILICITY; MEASUREMENT; PLASTICITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; STRUCTURE ANALYSIS; THERMODYNAMICS; TISSUE ENGINEERING; TISSUE STRUCTURE; VISCOELASTICITY; YOUNG MODULUS;

EID: 56349168856     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2008.07.019     Document Type: Article

References (39)

1. Murugan R., and Ramakrishna S. Development of nanocomposites for bone grafting. Compos Sci Technol 65 (2005) 2385-2406
2. Salgado A.J., Coutinho O.P., and Reis R.L. Bone tissue engineering: state of the art and future trends. Macromol Biosci 4 (2004) 743-765
3. Sharma B., and Elisseeff J.H. Engineering structurally organized cartilage and bone tissues. Ann Biomed Eng V32 (2004) 148-159
4. Mikos A.G., and Temenoff J.S. Formation of highly porous biodegradable scaffolds for tissue engineering. Electron J Biotechnol 3 (2000) 114-119
5. Laurencin C.T., Ambrosio A.M.A., Borden M.D., and Cooper J.A. Tissue engineering: orthopedic applications. Annu Rev Biomed Eng 1 (1999) 19
6. Murugan R., and Ramakrishna S. Nano-featured scaffolds for tissue engineering: a review of spinning methodologies. Tissue Eng 12 (2006) 435-447
7. Li W.-J., Laurencin C.T., Caterson E.J., Tuan R.S., and Ko F.K. Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Mater Res 60 (2002) 613-621
8. Huang Z.-M., Zhang Y.Z., Kotaki M., and Ramakrishna S. A review on polymer nanofibers by electrospinning and their applications in nanocomposites. Compos Sci Technol 63 (2003) 2223-2253
9. Xu C., Inai R., Kotaki M., and Ramakrishna S. Electrospun nanofiber fabrication as synthetic extracellular matrix and its potential for vascular tissue engineering. Tissue Eng 10 (2004) 1160-1168
10. Wang M. Developing bioactive composite materials for tissue replacement. Biomaterials 24 (2003) 2133-2151
11. Webster T.J., Ergun C., Doremus R.H., Siegel R.W., and Bizios R. Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics. J Biomed Mater Res 51 (2000) 475-483
12. Zhang N., Nichols H.L., Tylor S., and Wen X. Fabrication of nanocrystalline hydroxyapatite doped degradable composite hollow fiber for guided and biomimetic bone tissue engineering. Mater Sci Eng C-Biomim Supramol Syst 27 (2007) 599-606
13. Ural E., Kesenci K., Fambri L., Migliaresi C., and Piskin E. Poly(d,l-lactide/ε-caprolactone)/hydroxyapatite composites. Biomaterials 21 (2000) 2147-2154
14. Ito Y., Hasuda H., Kamitakahara M., Ohtsuki C., Tanihara M., Kang I.-K., et al. A composite of hydroxyapatite with electrospun biodegradable nanofibers as a tissue engineering material. J Biosci Bioeng 100 (2005) 43-49
15. Kim H.-W., Lee H.-H., and Knowles J.C. Electrospinning biomedical nanocomposite fibers of hydroxyapatite/poly(lactic acid) for bone regeneration. J Biomed Mater Res A 79A (2006) 643-649
16. Thomas V., Dean D.R., Jose M.V., Mathew B., Chowdhury S., and Vohra Y.K. Nanostructured biocomposite scaffolds based on collagen coelectrospun with nanohydroxyapatite. Biomacromolecules (2007)
17. Thomas V., Jagani S., Johnson K., Jose M.V., Dean D.R., Vohra Y.K., et al. Electrospun bioactive nanocomposite scaffolds of polycaprolactone and nanohydroxyapatite for bone tissue engineering. J Nanosci Nanotechnol 6 (2006) 487-493
18. Deng X.-L., Sui G., Zhao M.-L., Chen G.-Q., and Yang X.-P. Poly(l-lactic acid)/hydroxyapatite hybrid nanofibrous scaffolds prepared by electrospinning. J Biomater Sci Polym Ed 18 (2007) 117-130
19. Kim H.-W., Song J.H., and Kim H.E. Nanofiber generation of gelatin-hydroxyapatite biomimetics for guided tissue regeneration. Adv Funct Mater 15 (2005) 1988-1994
20. Bishop A., Balázsi C., Yang J.H.C., and Gouma P.-I. Biopolymer-hydroxyapatite composite coatings prepared by electrospinning. Polym Adv Technol 17 (2006) 902-906
21. Xu C.Y., Inai R., Kotaki M., and Ramakrishna S. Aligned biodegradable nanofibrous structure: a potential scaffold for blood vessel engineering. Biomaterials 25 (2004) 877-886
22. Lee C.H., Shin H.J., Cho I.H., Kang Y.-M., Kim I.A., Park K.-D., et al. Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast. Biomaterials 26 (2005) 1261-1270
23. Yang F., Murugan R., Wang S., and Ramakrishna S. Electrospinning of nano/micro scale poly(l-lactic acid) aligned fibers and their potential in neural tissue engineering. Biomaterials 26 (2005) 2603-2610
24. Zhong S., Teo W.E., Zhu X., Beuerman R.W., Ramakrishna S., and Yung L.Y.L. An aligned nanofibrous collagen scaffold by electrospinning and its effects on in vitro fibroblast culture. J Biomed Mater Res A 79 (2006) 456-463
25. Li W.-J., Mauck R.L., Cooper J.A., Yuan X., and Tuan R.S. Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering. J Biomech 40 (2007) 1686-1693
26. Zhu B., Lu Q., Yin J., Hu J., and Wang Z. Alignment of osteoblast-like cells and cell-produced collagen matrix induced by nanogrooves. Tissue Eng 11 (2005) 825-834
27. Thomas V., Jose M.V., Chowdhury S., Sullivan J.F., Dean D.R., and Vohra Y.K. Mechano-morphological studies of aligned nanofibrous scaffolds of polycaprolactone fabricated by electrospinning. J Biomater Sci Polym Ed V17 (2006) 969-984
28. Loo S.C.J., Ooi C.P., Wee S.H.E., and Boey Y.C.F. Effect of isothermal annealing on the hydrolytic degradation rate of poly(lactide-co-glycolide) (PLGA). Biomaterials 26 (2005) 2827-2833
29. Nie H., and Wang C.-H. Fabrication and characterization of PLGA/HAp composite scaffolds for delivery of BMP-2 plasmid DNA. J Control Release 120 (2007) 111-121
30. Cordewener F.W., Dijkgraaf L.C., Ong J.L., Agrawal C.M., Zardeneta G., Milam S.B., et al. Particulate retrieval of hydrolytically degraded poly(lactide-co-glycolide) polymers. J Biomed Mater Res 50 (2000) 59-66
31. You Y., Lee S.J., Min B.-M., and Park W.H. Effect of solution properties on nanofibrous structure of electrospun poly(lactic-co-glycolic acid). J Appl Polym Sci 99 (2006) 1214-1221
32. Smith L.A., and Ma P.X. Nano-fibrous scaffolds for tissue engineering. Colloids Surf B Biointerfaces 39 (2004) 125-131
33. Jose M.V., Steinert B.W., Thomas V., Dean D.R., Abdalla M.A., Price G., et al. Morphology and mechanical properties of Nylon 6/MWNT nanofibers. Polymer 48 (2007) 1096-1104
34. Park P.I.P., and Jonnalagadda S. Predictors of glass transition in the biodegradable polylactide and poly-lactide-co-glycolide polymers. J Appl Polym Sci 100 (2006) 1983-1987
35. Zong X., Ran S., Kim K.-S., Fang D., Hsiao B.S., and Chu B. Structure and morphology changes during in vitro degradation of electrospun poly(glycolide-co-lactide) nanofiber membrane. Biomacromolecules 4 (2003) 416-423
36. Zong X., Kim K., Fang D., Ran S., Hsiao B.S., and Chu B. Structure and process relationship of electrospun bioabsorbable nanofiber membranes. Polymer 43 (2002) 4403-4412
37. Dean D., Husband M., and Trimmer M. Time-temperature-dependent behavior of a substituted poly(paraphenylene): tensile, creep, and dynamic mechanical properties in the glassy state. J Polym Sci Polym Phys 36 (1998) 2971-2979
38. Lu L., Peter S.J., Lyman M.D., Lai H.-L., Leite S.M., Tamada J.A., et al. In vitro and in vivo degradation of porous poly(-lactic-co-glycolic acid) foams. Biomaterials 21 (2000) 1837-1845
39. Yang F., Cui W., Xiong Z., Liu L., Bei J., and Wang S. Poly(l,l-lactide-co-glycolide)/tricalcium phosphate composite scaffold and its various changes during degradation in vitro. Polym Degrad Stabil 91 (2006) 3065-3073