Transformation of p53-positive papillary thyroid carcinoma to anaplastic carcinoma of the liver following postoperative radioactive iodine-131 therapy

Internal Medicine

Volumn 47, Issue 19, 2008, Pages 1709-1712

  Takeshita, Yumie ^a   Takamura, Toshinari ^a   Minato, Hiroshi ^b   Misu, Hirofumi ^a   Ando, Hitoshi ^a   Yamashita, Tatsuya ^a   Ikeda, Hiroko ^a   Nakanuma, Yasuni ^a   Kaneko, Shuichi ^a  

^a KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^b KANAZAWA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Anaplastic transformation; Differentiated thyroid carcinoma; Iodine 131 therapy; Liver; p53 mutations

Indexed keywords

IODINE 131; PACLITAXEL; PROTEIN P53;

AGED; ANAPLASTIC CARCINOMA; ARTICLE; CANCER CHEMOTHERAPY; CASE REPORT; CAUSE OF DEATH; COMPUTER ASSISTED TOMOGRAPHY; CONTINUOUS INFUSION; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LABORATORY TEST; LIVER BIOPSY; LIVER CARCINOMA; LIVER METASTASIS; MALIGNANT TRANSFORMATION; PHYSICAL EXAMINATION; POSTOPERATIVE CARE; RADIOFREQUENCY ABLATION; RESPIRATORY FAILURE; THYROID PAPILLARY CARCINOMA; THYROIDECTOMY;

AGED; AGED, 80 AND OVER; ANAPLASIA; CARCINOMA, PAPILLARY; COMBINED MODALITY THERAPY; FEMALE; GENES, P53; HUMANS; IODINE RADIOISOTOPES; LIVER NEOPLASMS; MUTATION; THYROID NEOPLASMS; THYROIDECTOMY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 56349112761     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.47.1190     Document Type: Article

References (19)

1. Wood WJ, Singletary SE, Hickey RC. Current results of the treatment for the distant metastatic well-differentiated thyroid carcinoma. Arch Surg 124: 1374-1377, 1989.
2. Silliphant WM, Klinck GH, Levitin MS. Thyroid carcinoma and death. A clinicopathological study of 193 autopsies. Cancer 17: 513-525, 1964.
3. Ohwada S, Iino Y, Hosomura Y, et al. Solitary metastasis from papillary thyroid carcinoma in cirrhotic liver with hepatocellular carcinoma. Jpn J Clin Oncol 23: 309-312, 1993.
4. Ain KB, Egorin MJ, DeSimone PA. Treatment of anaplastic thyroid carcinoma with paclitaxel: phase 2 trial using ninety-six-hour infusion. Thyroid 10: 587-594, 2000.
5. Woolner LB, Beahrs OH, Black BM, McConahey WM, Keating FR. Classification and prognosis of thyroid carcinoma: a study of 885 cases observed in a thirty-year period. Am J Surg 102: 354-355, 1961.
6. Harada T, Mimura T, Ito K, et al. Divergent histology in the primary and metastatic lesions of thyroid carcinoma. Nippon Geka Gakkai Zasshi 84: 758-761, 1983 (in Japanese).
7. Niederle B, Roka R, Schemper M, Fritsh A, Weissel M, Ramach W. Surgical treatment of distant metastases in differentiated thyroid cancer: indications and results. Surgery 100: 1088-1096, 1986.
8. Venkatesh YS, Ordonez NG, Schultz PN, Hickey RC, Goepfert H, Samaan NA. Anaplastic carcinoma of the thyroid. A clinicopathologic study of 121 cases. Cancer 66: 321-330, 1990.
9. Vassilopoulou-Sellin R, Schultz PN, Haynie TP. Clinical outcome of patients with papillary thyroid carcinoma who have recurrence after initial radioactive iodine therapy. Cancer 78: 493-501, 1996.
10. Williams ED. Thyroid cancer: pathologic and natural history. Recent Results Cancer Res 73: 47-55, 1980.
11. 131I) therapy. Thyroid 10: 975-979, 2000.
12. Sidransky D, Mikkellsen T, Schwechheimer K, Rosenblum ML, Cavanee W, Vogelstein B. Clonal expansion of p53 mutant cells is associated with brain tumor progression. Nature 355: 846-847, 1992.
13. Krokk TG. Molecular events in follicular thyroid tumors. Cancer Treat Res 122: 85-105, 2004.
14. Omar E, Madhavan M, Othman NH. Immunohistochemical localisation of RET and p53 mutant protein of thyroid lesions in a north-eastern Malaysian population and its prognostic implications. Pathology 36: 152-192, 2004.
15. Minjing Z, Yufei S, Nadir RF. p53 mutations in all stages of thyroid carcinomas. J Clin Endocrinol Metab 77: 1054-1058, 1993.
16. Nishida T, Nakao K, Hamaji M, Nakahara M, Tsujimoto M. Over-expression of p53 protein and DNA content are important biologic prognostic factors for thyroid cancer. Surgery 119: 568-575, 1996.
17. Ito T, Seyama T, Mizuno T, et al. Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland. Cancer Res 52: 1369-1372, 1992.
18. Nakashima M, Takamura N, Namba H, et al. RET oncogene amplification in thyroid cancer: correlations with radiation-associated and high-grade malignancy. Hum Pathol 38: 621-628, 2007.
19. Shingu K, Kobayashi S, Yokoyama S, et al. The likely transformation of papillary thyroid carcinoma into anaplastic carcinoma during postoperative radioactive iodine-131 therapy: report of a case. Surg Today 30: 910-913, 2000.