Polar emollients in cosmetic formulations enhance the penetration and biological effects of Phytosphingosine on skin

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Volumn 331, Issue 1-2, 2008, Pages 103-107

  Schiemann, Y ^a   Wegmann, M ^a   Lersch, P ^a   Heisler, E ^b   Farwick, M ^a  

^a EVONIK INDUSTRIES AG   (Germany)

^b Evonik Stockhausen GmbH   (Germany)

Author keywords

Differentiation; Franz cell; Penetration; Phytosphingosine; Skin model

Indexed keywords

ACIDS; AMIDES; BIOACTIVITY; BIOCHEMISTRY; BIOLOGICAL RADIATION EFFECTS; CELLS; CYTOLOGY; DIFFERENTIATION (CALCULUS); FATTY ACIDS; GENE EXPRESSION; GENES; NUCLEIC ACIDS; ORGANIC ACIDS; PROBABILITY DENSITY FUNCTION;

DIFFERENTIATION; FRANZ CELL; PENETRATION; PHYTOSPHINGOSINE; SKIN MODEL;

SKIN;

CERAMIDE; COSMETIC; EMOLLIENT AGENT; FATTY ACID; PHYTOSPHINGOSINE;

ADULT; AMIDATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CELL CULTURE; CELL DIFFERENTIATION; COSMETIC INDUSTRY; DNA MICROARRAY; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG PENETRATION; EPIDERMIS; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RNA TRANSLATION; SKIN ABSORPTION; SKIN PROTECTION; SWINE;

EID: 56249143068     PISSN: 09277757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfa.2008.07.015     Document Type: Article

References (21)

1. Chuong C.M., Nickoloff B.J., Elias P.M., Goldsmith L.A., Macher E., Maderson P.A., Sundberg J.P., Tagami H., Plonka P.M., Thestrup-Pedersen K., Bernard B.A., Schröder J.M., Dotto P., Chang C.H., Williams M.L., Feingold K.R., King L.E., Kligman A.M., Rees J.L., and Christophers E. What is the 'true' function of skin?. Exp. Dermatol. 11 (2002) 159-187
2. Wokalek H., and Die Haut. In: Niedner (Hrsg.) R., and Ziegenmeyer (Hrsg.) J. (Eds). Dermatika (1992), Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart
3. W. Wohlrab, Pharmakokinetik in der Haut, N. W. Neubert, W. Wohlrab, Marsch (Hrsg.), Dermatopharmazie Wissenschaftliche Verlagsgesellschaft mbH Stuttgart, (2001) 139-162.
4. Ponec M., et al. Barrier function in reconstructed epidermis and its resemblance to native human skin. Skin Pharmacol. Appl. Skin Physol. 14 (2001) 63-71
5. Bo Nielsen J., Nielsen F., and Ahm Sorensen J. In vitro percutaneous penetration of five pesticides-effects of molecular weight and solubility characteristics. Ann. Hyg. 48 (2004) 697-705
6. Berardesca E., Barbareschi M., Veraldi S., and Pimpinelli N. Evaluation of efficacy of a skin lipid mixture in patients with irritant contact dermatitis, allergic contact dermatitis or atopic dermatitis: a multicenter study. Contact Dermatitis 45 5 (2001) 280-285
7. Pavicic T., Wollenweber U., Farwick M., and Korting H. Anti-microbial and -inflammatory activity and efficacy of Phytosphingosine: an in vitro and in vivo study addressing acne vulgaris. Int. J Cosmetic Sci 29 3 (2007) 181-190 (10)
8. Kim S., Hong I., Sun Hwang J., Kyu Choi J., Sik Rho H., Hee Kim D., Chang I., Hun Lee S., Ock Lee M., and Sung Hwang J. Phytosphingosine stimulates the differentiation of human keratinocytes and inhibits TPA-induced inflammatory epidermal hyperplasia in hairless mouse skin. Mol. Med. 12 1-3 (2006) 17-24
9. Bustin S.A. Quantification of mRNA using real-time reverse transcription PCR (RT-PCR):trends and problems. J. Mol. Endocrinol. 29 (2002) 23-39
10. Cannon C.L., et al. New epidermal model for dermal irritancy testing. Toxicol. in vitro 8 (1994) 889-891
11. Freeman W.M., Walker S.J., and Vrana K.E. Quantitative RT-PCR: pitfalls and potential. Biotechniques 26 (1999) 112-115
12. Heid C.A., Stevens J., Livak K.J., and Williams P.M. Real time quantitative PCR. Genome Res. 6 (1996) 986-994
13. Chuaqui F., Bonner R.F., Best C.J.M., Gillespie J.W., Flaig M.J., Hewitt S.M., Phillips J.L., Krizman D.B., Tangrea M.A., Ahram M., Linehan W.M., Knezevic V., and Emmert-Buck M.R. Post-analysis follow-up and validation of microarray experiments. Nat. Genet. Suppl. 32 (2002) 509-514
14. Mullis K.B., and Faloona F.A. Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol. 155 (1986) 366
15. Schulze A., and Downward J. Navigating gene expression using microarrays-a technology review. Nat Cell Biol. 3 (2001) 190-195
16. Langmann T., Moehle C., Mauerer R., Scharl M., Liebisch G., Zahn A., et al. Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes. Gastroenterology 127 (2004) 26-40
17. OECD, Test Guideline 428: Skin Absorption: in vitro Method, Adopted on 13th April, (2004b).
18. Wells T., Basketter D.A., and Schröder K.R. In vitro skin irritation: facts & future: state of the art review of mechanisms and models. Toxicology In Vitro 18 (2004) 231-243
19. G. Paragh, P. Schling, P. Ugocsai, A.E. Kel, G. Liebisch, S. Heimerl, C. Moehle, Y. Schiemann, M. Wegmann, M. Farwick, M. Wikonkal, J. Mandl, T. Langmann,G. Schmitz, Novel sphinolipid derivatives promote keratinocyte differentiation, Exp. Dermatol., in press.
20. Wiechers J.W. The influence of emollients on skin penetration. Cosmetic Toiletries 123 1 (2008) 46-54
21. Wiechers J.W., Kelly C.L., and Blease T.G. Formulation for efficacy. Cosmetic Toiletries 119 3 (2004) 49-62