Triterpene based compounds with potent anti-maturation activity against HIV-1

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 24, 2008, Pages 6377-6380

  Gerrish, David ^a   Kim, In Chul ^a   Kumar, Dange V ^a   Austin, Harry ^a   Garrus, Jennifer E ^a   Baichwal, Vijay ^a   Saunders, Michael ^a   McKinnon, Rena S ^a   Anderson, Mark B ^a   Carlson, Robert ^a   Arranz Plaza, Esther ^a   Yager, Kraig M ^a  

^a Myriad Pharmaceuticals   (United States)

Author keywords

Anti viral; Betulinic acid; HIV 1; Maturation inhibitor; Triterpene

Indexed keywords

ANTIVIRUS AGENT; BETULIC ACID; BEVIRIMAT; TRITERPENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG POTENCY; DRUG STRUCTURE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; MALE; NONHUMAN; PHYSICAL CHEMISTRY; RAT; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; AMIDES; ANIMALS; ANTI-HIV AGENTS; ANTIVIRAL AGENTS; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HIV-1; HUMANS; INHIBITORY CONCENTRATION 50; LEUKOCYTES, MONONUCLEAR; MODELS, CHEMICAL; RATS; TERPENES; TRITERPENES;

HUMAN IMMUNODEFICIENCY VIRUS 1; RATTUS;

EID: 56249126754     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.098     Document Type: Article

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