A facile synthesis, antibacterial, and antitubercular studies of some piperidin-4-one and tetrahydropyridine derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 24, 2008, Pages 6542-6548

  Aridoss, Gopalakrishnan ^a   Amirthaganesan, Shanmugasundaram ^a   Ashok Kumar, Nanjundan ^a   Kim, Jong Tae ^a   Lim, Kwon Taek ^a   Kabilan, Senthamaraikannan ^b   Jeong, Yeon Tae ^a  

^a Pukyong National University   (South Korea)

^b ANNAMALAI UNIVERSITY   (India)

Author keywords

Antibacterial activity; Antitubercular activity; Benzimidazole; Crystal structure; Sulfonate; Tetrahydropyridine

Indexed keywords

ANTIINFECTIVE AGENT; LINEZOLID; N CHLOROACETYL 3 CARBOXYETHYL 2,6 DIPHENYL 4 HYDROXY DELTA3 TETRAHYDROPYRIDINE; PIPERIDIN 4 ONE DERIVATIVE; PIPERIDINE DERIVATIVE; PYRIDINE DERIVATIVE; RIFAMPICIN; TETRAHYDROPYRIDINE DERIVATIVE; TROVAFLOXACIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG POTENCY; DRUG SYNTHESIS; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; STAPHYLOCOCCUS AUREUS; X RAY CRYSTALLOGRAPHY;

ANTI-BACTERIAL AGENTS; ANTITUBERCULAR AGENTS; CHEMISTRY, PHARMACEUTICAL; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; DRUG RESISTANCE, MICROBIAL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MODELS, CHEMICAL; MODELS, MOLECULAR; PIPERIDINES; PIPERIDONES; PYRIDINES; RIFAMPIN;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; MYCOBACTERIUM TUBERCULOSIS; STAPHYLOCOCCUS AUREUS;

EID: 56249114531     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.045     Document Type: Article

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