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Volumn 876, Issue 1, 2008, Pages 47-53
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Characterization of the in vivo and in vitro metabolic profile of PAC-1 using liquid chromatography-mass spectrometry
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Author keywords
Ion trap; Metabolite identification; PAC 1; TOF MS
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Indexed keywords
ACIDS;
BIOMOLECULES;
BODY FLUIDS;
CHEMICAL ANALYSIS;
CHROMATOGRAPHIC ANALYSIS;
CHROMATOGRAPHY;
FORMIC ACID;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HYDROXYLATION;
IONS;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
METABOLITES;
METHANOL;
ORGANIC ACIDS;
SPECTROMETERS;
SPECTROMETRY;
ACCURATE MASS MEASUREMENTS;
AGILENT;
ANTI-CANCER DRUGS;
CHROMATOGRAPHIC SYSTEMS;
DEBENZYLATION;
DIHYDROXYLATION;
ELEMENTAL COMPOSITIONS;
GLUCURONIDE;
IN VITRO;
IN-VIVO;
ION TRAP;
ION TRAPS;
METABOLIC CHANGES;
METABOLIC PATHWAYS;
METABOLIC PROFILES;
METABOLITE ANALYSES;
METABOLITE IDENTIFICATION;
PAC-1;
PHASE I;
PHASE II;
PRODUCT ION SPECTRUMS;
QUADRUPOLE;
STRUCTURAL INFORMATIONS;
TIME OF FLIGHTS;
TOF/MS;
LIQUID CHROMATOGRAPHY;
(4 BENZYLPIPERAZIN 1 YL)ACETIC ACID (3 ALLYL 2 HYDROXY BENZYLIDENE)HYDRAZINE;
ANTINEOPLASTIC AGENT;
FORMIC ACID;
METHANOL;
UNCLASSIFIED DRUG;
WATER;
ANIMAL EXPERIMENT;
ANIMAL TISSUE;
ARTICLE;
CONTROLLED STUDY;
DEBENZYLATION;
DIHYDROXYLATION;
DRUG IDENTIFICATION;
DRUG STRUCTURE;
FECES ANALYSIS;
HYDROXYLATION;
IN VITRO STUDY;
IN VIVO STUDY;
ION TRAP MASS SPECTROMETRY;
LIQUID CHROMATOGRAPHY;
MALE;
MASS SPECTROMETRY;
NONHUMAN;
PRIORITY JOURNAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
QUADRUPOLE MASS SPECTROMETRY;
RAT;
SINGLE DRUG DOSE;
TIME OF FLIGHT MASS SPECTROMETRY;
URINALYSIS;
ANIMALS;
ANTINEOPLASTIC AGENTS;
BIOTRANSFORMATION;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
FECES;
HYDRAZONES;
MALE;
METABOLOME;
MICROSOMES, LIVER;
PIPERAZINES;
RATS;
RATS, WISTAR;
TANDEM MASS SPECTROMETRY;
RATTUS;
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EID: 56249112955
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2008.10.006 Document Type: Article |
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Times cited : (15)
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References (17)
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