메뉴 건너뛰기




Volumn 141, Issue 2, 2008, Pages 158-162

Intravaginally applied metronidazole is as effective as orally applied in the treatment of bacterial vaginosis, but exhibits significantly less side effects

Author keywords

Adverse events; Antibiotic; Oral; Therapy; Vaginal

Indexed keywords

ARILIN RAPID; METRONIDAZOLE; UNCLASSIFIED DRUG;

EID: 56249098996     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2008.07.022     Document Type: Article
Times cited : (56)

References (26)
  • 1
    • 0029834536 scopus 로고    scopus 로고
    • Defining bacterial vaginosis: to BV or not to BV, that is the question
    • Hay P.E., and Taylor-Robinson D. Defining bacterial vaginosis: to BV or not to BV, that is the question. Int J STD AIDS 7 (1996) 233-235
    • (1996) Int J STD AIDS , vol.7 , pp. 233-235
    • Hay, P.E.1    Taylor-Robinson, D.2
  • 2
    • 33748888743 scopus 로고    scopus 로고
    • Clinical practice. Acute vulvovaginitis
    • Eckert L.O. Clinical practice. Acute vulvovaginitis. N Engl J Med 21 355 (2006) 1244-1252
    • (2006) N Engl J Med , vol.21 , Issue.355 , pp. 1244-1252
    • Eckert, L.O.1
  • 5
    • 21344455107 scopus 로고    scopus 로고
    • Bacterial vaginosis-a disturbed bacterial flora and treatment enigma
    • Larsson P.G., and Forsum U. Bacterial vaginosis-a disturbed bacterial flora and treatment enigma. APMIS 113/5 (2005) 305-316
    • (2005) APMIS , vol.113-5 , pp. 305-316
    • Larsson, P.G.1    Forsum, U.2
  • 6
    • 0031417333 scopus 로고    scopus 로고
    • Six years observation after successful treatment of bacterial vaginosis
    • Boris J., Pahlson C., and Larsson P.-G. Six years observation after successful treatment of bacterial vaginosis. Infect Dis Obstet Gynecol 5 (1997) 297-302
    • (1997) Infect Dis Obstet Gynecol , vol.5 , pp. 297-302
    • Boris, J.1    Pahlson, C.2    Larsson, P.-G.3
  • 7
    • 7044272503 scopus 로고    scopus 로고
    • Antimicrobial resistance associated with the treatment of bacterial vaginosis
    • Beigi R.H., Austin M.N., Meyn L.A., Krohn M., and Hillier S.L. Antimicrobial resistance associated with the treatment of bacterial vaginosis. Am J Obstet Gynecol 191 (2004) 1124-1129
    • (2004) Am J Obstet Gynecol , vol.191 , pp. 1124-1129
    • Beigi, R.H.1    Austin, M.N.2    Meyn, L.A.3    Krohn, M.4    Hillier, S.L.5
  • 8
    • 56249095912 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention, Guidelines and treatment of sexually transmitted diseases: MMWR Recommendations and Report 2006, 55(RR11):1-94.
    • Centers for Disease Control and Prevention, Guidelines and treatment of sexually transmitted diseases: MMWR Recommendations and Report 2006, 55(RR11):1-94.
  • 9
    • 56249139106 scopus 로고    scopus 로고
    • AWMF-Reg.-Nr. 015/028, Empfehlungen zur bakteriellen Vaginose in Gynäkologie und Geburtshilfe, www.leitlinien.net; 2006.
    • AWMF-Reg.-Nr. 015/028, Empfehlungen zur bakteriellen Vaginose in Gynäkologie und Geburtshilfe, www.leitlinien.net; 2006.
  • 10
    • 33645474076 scopus 로고    scopus 로고
    • Choosing the analysis population in non-inferiority studies: per protocol or intent-to-treat
    • Matilde Sanchez M., and Chen X. Choosing the analysis population in non-inferiority studies: per protocol or intent-to-treat. Stat Med 25 (2006) 1169-1181
    • (2006) Stat Med , vol.25 , pp. 1169-1181
    • Matilde Sanchez, M.1    Chen, X.2
  • 11
    • 11344257356 scopus 로고    scopus 로고
    • A comparison of intent-to-treat and per-protocol results in antibiotic non-inferiority trials
    • Brittain E., and Lin D. A comparison of intent-to-treat and per-protocol results in antibiotic non-inferiority trials. Stat Med 24 (2005) 1-10
    • (2005) Stat Med , vol.24 , pp. 1-10
    • Brittain, E.1    Lin, D.2
  • 12
    • 0025285004 scopus 로고
    • Treatment of bacterial vaginosis in women with vaginal bleeding complications or discharge and harbouring Mobiluncus
    • Larsson P.G., Bergman B., Forsum U., and Pahlson C. Treatment of bacterial vaginosis in women with vaginal bleeding complications or discharge and harbouring Mobiluncus. Gynecol Obstet Invest 29 (1990) 296-300
    • (1990) Gynecol Obstet Invest , vol.29 , pp. 296-300
    • Larsson, P.G.1    Bergman, B.2    Forsum, U.3    Pahlson, C.4
  • 13
    • 0027263644 scopus 로고
    • Efficacy of intravaginal 0.75% metronidazole gel for the treatment of bacterial vaginosis
    • Hillier S.L., Lipinski C., Briselden A.M., and Eschenbach D.A. Efficacy of intravaginal 0.75% metronidazole gel for the treatment of bacterial vaginosis. Am J Obstet Gynecol 81 (1993) 963-967
    • (1993) Am J Obstet Gynecol , vol.81 , pp. 963-967
    • Hillier, S.L.1    Lipinski, C.2    Briselden, A.M.3    Eschenbach, D.A.4
  • 15
    • 10044289884 scopus 로고    scopus 로고
    • Safety and efficacy of MetroGel-Vaginal(R) in the treatment of bacterial vaginosis: a multicenter, randomized, single-blind, parallel comparison
    • Soper D.E., Livengood C., Sheehan K.L., Fenner D.E., Martens M.G., Nelson A.L., et al. Safety and efficacy of MetroGel-Vaginal(R) in the treatment of bacterial vaginosis: a multicenter, randomized, single-blind, parallel comparison. Prim Care Update Ob Gyns 5 (1998) 150
    • (1998) Prim Care Update Ob Gyns , vol.5 , pp. 150
    • Soper, D.E.1    Livengood, C.2    Sheehan, K.L.3    Fenner, D.E.4    Martens, M.G.5    Nelson, A.L.6
  • 16
    • 0033062602 scopus 로고    scopus 로고
    • Comparison of once-daily and twice-daily dosing of 0.75% metronidazole gel in the treatment of bacterial vaginosis
    • Livengood III C.H., Soper D.E., Sheehan K.L., Fenner D.E., Martens M.G., Nelson A.L., et al. Comparison of once-daily and twice-daily dosing of 0.75% metronidazole gel in the treatment of bacterial vaginosis. Sex Transm Dis 26 (1999) 137-142
    • (1999) Sex Transm Dis , vol.26 , pp. 137-142
    • Livengood III, C.H.1    Soper, D.E.2    Sheehan, K.L.3    Fenner, D.E.4    Martens, M.G.5    Nelson, A.L.6
  • 20
    • 33646118730 scopus 로고    scopus 로고
    • Suppressive antibacterial therapy with 0.75% metronidazole vaginal gel to prevent recurrent bacterial vaginosis
    • Sobel J.D., Ferris D., Schwebke J., et al. Suppressive antibacterial therapy with 0.75% metronidazole vaginal gel to prevent recurrent bacterial vaginosis. Am J Obstet Gynecol 194 5 (2006) 1283-1289
    • (2006) Am J Obstet Gynecol , vol.194 , Issue.5 , pp. 1283-1289
    • Sobel, J.D.1    Ferris, D.2    Schwebke, J.3
  • 21
    • 84944281939 scopus 로고
    • Comparison of single-dose vs one-week course of metronidazole for symptomatic bacterial vaginosis
    • Swedberg J., Steiner J.F., Tackwell K.R., and Batts D.H. Comparison of single-dose vs one-week course of metronidazole for symptomatic bacterial vaginosis. JAMA 254 (1985) 1046-1049
    • (1985) JAMA , vol.254 , pp. 1046-1049
    • Swedberg, J.1    Steiner, J.F.2    Tackwell, K.R.3    Batts, D.H.4
  • 22
    • 56249133080 scopus 로고
    • Bacterial vaginosis: treatment with clindamycin cream versus oral metronidazole
    • Schmitt C., Sobel J.D., and Merlwether C. Bacterial vaginosis: treatment with clindamycin cream versus oral metronidazole. Obstet Gynecol 85 (1992) 1077-1080
    • (1992) Obstet Gynecol , vol.85 , pp. 1077-1080
    • Schmitt, C.1    Sobel, J.D.2    Merlwether, C.3
  • 23
    • 0033933113 scopus 로고    scopus 로고
    • Vaginal clindamycin and oral metronidazole for bacterial vaginosis: a randomized trial
    • Paavonen J., Mangioni C., Martin M.A., and Wajszczuk C.P. Vaginal clindamycin and oral metronidazole for bacterial vaginosis: a randomized trial. Obstet Gynecol 96 (2000) 256-260
    • (2000) Obstet Gynecol , vol.96 , pp. 256-260
    • Paavonen, J.1    Mangioni, C.2    Martin, M.A.3    Wajszczuk, C.P.4
  • 25
    • 0024595049 scopus 로고
    • Treatment of bacterial vaginosis with intravaginal sponges containing metronidazole
    • Edelman D.A., and North B.B. Treatment of bacterial vaginosis with intravaginal sponges containing metronidazole. J Reprod Med 34 (1989) 341-344
    • (1989) J Reprod Med , vol.34 , pp. 341-344
    • Edelman, D.A.1    North, B.B.2
  • 26
    • 0028842572 scopus 로고
    • Treatment of bacterial vaginosis: a comparison of oral metronidazole, metronidazole vaginal gel, and clindamycin vaginal cream
    • Ferris D.G., Litaker M.S., Woodward L., Mathis D., and Hendrich J. Treatment of bacterial vaginosis: a comparison of oral metronidazole, metronidazole vaginal gel, and clindamycin vaginal cream. J Fam Pract 41/5 (1995) 443-449
    • (1995) J Fam Pract , vol.41-5 , pp. 443-449
    • Ferris, D.G.1    Litaker, M.S.2    Woodward, L.3    Mathis, D.4    Hendrich, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.