3,4-Dihydroxyphenylacetic acid (DOPAC) modulates the toxicity induced by nitric oxide in PC-12 cells via mitochondrial dysfunctioning

NeuroToxicology

Volumn 29, Issue 6, 2008, Pages 998-1007

  Nunes, Carla ^a   Almeida, Leonor ^a   Laranjinha, João ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

DOPAC; Mitochondrial dysfunction; Nitric oxide; Parkinson's disease; PC 12 cells; Programmed cell death; Synergism

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; ADENOSINE TRIPHOSPHATE; APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 9; CYTOCHROME C; DOPAMINE; LACTATE DEHYDROGENASE; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOBLOTTING; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT;

3,4-DIHYDROXYPHENYLACETIC ACID; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS INDUCING FACTOR; CASPASES; CELL DEATH; CELL SIZE; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FREE RADICAL SCAVENGERS; L-LACTATE DEHYDROGENASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NITRIC OXIDE; PC12 CELLS; PENICILLAMINE; RATS;

EID: 56249095456     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2008.07.003     Document Type: Article

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