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Volumn 248, Issue 5, 2008, Pages 821-828

Single administration of thrombopoietin prevents progression of liver fibrosis and promotes liver regeneration after partial hepatectomy in cirrhotic rats

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFIBROTIC AGENT; CYTOGLOBIN; PLATELET DERIVED GROWTH FACTOR; RECOMBINANT MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; SCATTER FACTOR; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; MACROGOL DERIVATIVE; POLYETHYLENE GLYCOL RECOMBINANT HUMAN MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; POLYETHYLENE GLYCOL-RECOMBINANT HUMAN MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; RECOMBINANT PROTEIN; THROMBOPOIETIN;

EID: 56149114401     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e31818584c7     Document Type: Article
Times cited : (70)

References (47)
  • 1
    • 3543098600 scopus 로고    scopus 로고
    • Liver ?brosis: From the bench to clinical targets
    • Pinzani M, Rombouts K. Liver ?brosis: from the bench to clinical targets. Dig Liver Dis. 2004;36:231-242.
    • (2004) Dig Liver Dis , vol.36 , pp. 231-242
    • Pinzani, M.1    Rombouts, K.2
  • 2
    • 0025217055 scopus 로고
    • Primary liver cancer in Japan. Clinicopathologic features and results of surgical treatment
    • Liver Cancer Study Group of Japan
    • Liver Cancer Study Group of Japan. Primary liver cancer in Japan. Clinicopathologic features and results of surgical treatment. Ann Surg. 1990;211:277-287.
    • (1990) Ann Surg , vol.211 , pp. 277-287
  • 3
    • 0035019334 scopus 로고    scopus 로고
    • Hepatic ?brosis. Pathogenesis and principles of therapy
    • Albanis E, Friedman SL. Hepatic ?brosis. Pathogenesis and principles of therapy. Clin Liver Dis. 2001;5:315-334.
    • (2001) Clin Liver Dis , vol.5 , pp. 315-334
    • Albanis, E.1    Friedman, S.L.2
  • 4
    • 0033838920 scopus 로고    scopus 로고
    • The development and compensation of biliary cirrhosis in interleukin-6-de?cient mice
    • Ezure T, Sakamoto T, Tsuji H, et al. The development and compensation of biliary cirrhosis in interleukin-6-de?cient mice. Am J Pathol. 2000; 156:1627-1639.
    • (2000) Am J Pathol , vol.156 , pp. 1627-1639
    • Ezure, T.1    Sakamoto, T.2    Tsuji, H.3
  • 6
    • 0034007745 scopus 로고    scopus 로고
    • Liver regeneration
    • Fausto N. Liver regeneration. J Hepatol. 2000;32:19-31.
    • (2000) J Hepatol , vol.32 , pp. 19-31
    • Fausto, N.1
  • 7
    • 0001276586 scopus 로고
    • Experimental pathology of the liver
    • Higgins GM, Anderson RM. Experimental pathology of the liver. Arch Pathol. 1931;12:186-202.
    • (1931) Arch Pathol , vol.12 , pp. 186-202
    • Higgins, G.M.1    Anderson, R.M.2
  • 8
    • 0023189290 scopus 로고
    • Human liver regeneration after major hepatic resection: A study of normal liver and livers with chronic hepatitis and cirrhosis
    • Nagasue N, Yukaya H, Ogawa Y, et al. Human liver regeneration after major hepatic resection: a study of normal liver and livers with chronic hepatitis and cirrhosis. Ann Surg. 1987;206:30-39.
    • (1987) Ann Surg , vol.206 , pp. 30-39
    • Nagasue, N.1    Yukaya, H.2    Ogawa, Y.3
  • 9
    • 0033752004 scopus 로고    scopus 로고
    • Percutaneous portal vein embolization increases the feasibility and safety of major liver resection for hepatocellular carcinoma in injured livers
    • Azoulay D, Castaing D, Krissat J, et al. Percutaneous portal vein embolization increases the feasibility and safety of major liver resection for hepatocellular carcinoma in injured livers. Ann Surg. 2000;232:665-672.
    • (2000) Ann Surg , vol.232 , pp. 665-672
    • Azoulay, D.1    Castaing, D.2    Krissat, J.3
  • 10
    • 0037423786 scopus 로고    scopus 로고
    • A trial on regeneration therapy of rat liver cirrhosis by controlled release of hepatocyte growth factor
    • Oe S, Furunaka Y, Hirose T, et al. A trial on regeneration therapy of rat liver cirrhosis by controlled release of hepatocyte growth factor. J Control Release. 2003;88:193-200.
    • (2003) J Control Release , vol.88 , pp. 193-200
    • Oe, S.1    Furunaka, Y.2    Hirose, T.3
  • 11
    • 0033977472 scopus 로고    scopus 로고
    • The decrease in total collagen ?bers in the liver by hepatocyte growth factor after formation of cirrhosis induced by thioacetamine
    • Sato M, Kakubari M, Kawamura M, et al. The decrease in total collagen ?bers in the liver by hepatocyte growth factor after formation of cirrhosis induced by thioacetamine. Biochem Pharmacol. 2000;59:681-690.
    • (2000) Biochem Pharmacol , vol.59 , pp. 681-690
    • Sato, M.1    Kakubari, M.2    Kawamura, M.3
  • 12
    • 33646488688 scopus 로고    scopus 로고
    • Combination gene therapy of HGF and truncated type II TGF-β receptor for rat liver cirrhosis after partial hepatectomy
    • Ozawa S, Uchiyama K, Nakamori M, et al. Combination gene therapy of HGF and truncated type II TGF-β receptor for rat liver cirrhosis after partial hepatectomy. Surgery. 2006;139:563-573.
    • (2006) Surgery , vol.139 , pp. 563-573
    • Ozawa, S.1    Uchiyama, K.2    Nakamori, M.3
  • 13
    • 0032919122 scopus 로고    scopus 로고
    • Increased level of serum hepatocyte growth factor/scatter factor in liver cancer is associated with tumor metastasis
    • Junbo H, Li Q, Zaide W, et al. Increased level of serum hepatocyte growth factor/scatter factor in liver cancer is associated with tumor metastasis. In Vivo. 1999;13:177-180.
    • (1999) In Vivo , vol.13 , pp. 177-180
    • Junbo, H.1    Li, Q.2    Zaide, W.3
  • 14
    • 40049092502 scopus 로고    scopus 로고
    • Signi?cance of serum hepatocyte growth factor levels in patients with hepatocellular carcinoma undergoing hepatic resection
    • Chau GY, Lui WY, Chi CW, et al. Signi?cance of serum hepatocyte growth factor levels in patients with hepatocellular carcinoma undergoing hepatic resection. Eur J Surg Oncol. 2007;34:333-338.
    • (2007) Eur J Surg Oncol , vol.34 , pp. 333-338
    • Chau, G.Y.1    Lui, W.Y.2    Chi, C.W.3
  • 15
    • 33947676269 scopus 로고    scopus 로고
    • Platelets promote liver regeneration in early period after hepatectomy
    • Murata S, Ohkohchi N, Matsuo R, et al. Platelets promote liver regeneration in early period after hepatectomy. World J Surg. 2007;31:808-816.
    • (2007) World J Surg , vol.31 , pp. 808-816
    • Murata, S.1    Ohkohchi, N.2    Matsuo, R.3
  • 16
    • 40149102010 scopus 로고    scopus 로고
    • Platelets strongly induce hepatocyte proliferation with IGF-1 and HGF in vitro
    • Matsuo R, Ohkohchi N, Murata S, et al. Platelets strongly induce hepatocyte proliferation with IGF-1 and HGF in vitro. J Surg Res. 2008;145:279-286.
    • (2008) J Surg Res , vol.145 , pp. 279-286
    • Matsuo, R.1    Ohkohchi, N.2    Murata, S.3
  • 17
    • 36248939262 scopus 로고    scopus 로고
    • Freeze dried platelets promote hepatocyte proliferation in mice
    • Hoshi R, Murata S, Matsuo R, et al. Freeze dried platelets promote hepatocyte proliferation in mice. Cryobiology. 2007;55:255-260.
    • (2007) Cryobiology , vol.55 , pp. 255-260
    • Hoshi, R.1    Murata, S.2    Matsuo, R.3
  • 18
    • 33645666489 scopus 로고    scopus 로고
    • Platelet-derived serotonin mediates liver regeneration
    • Lesurtel M, Graf R, Aleil B, et al. Platelet-derived serotonin mediates liver regeneration. Science. 2006;312:104-107.
    • (2006) Science , vol.312 , pp. 104-107
    • Lesurtel, M.1    Graf, R.2    Aleil, B.3
  • 19
    • 43949097244 scopus 로고    scopus 로고
    • Platelets promote liver regeneration under conditions of Kupffer cell depletion after hepatectomy in mice
    • Murata S, Matsuo R, Ikeda O, et al. Platelets promote liver regeneration under conditions of Kupffer cell depletion after hepatectomy in mice. World J Surg. 2008;32:1088-1096.
    • (2008) World J Surg , vol.32 , pp. 1088-1096
    • Murata, S.1    Matsuo, R.2    Ikeda, O.3
  • 20
    • 0031965018 scopus 로고    scopus 로고
    • Multilineage hematopoietic recovery by a single injection of pegylated recombinant human megakaryocyte growth and development factor in myelosuppressed mice
    • Shibuya K, Akahori H, Takahashi K, et al. Multilineage hematopoietic recovery by a single injection of pegylated recombinant human megakaryocyte growth and development factor in myelosuppressed mice. Blood. 1998;91:37-45.
    • (1998) Blood , vol.91 , pp. 37-45
    • Shibuya, K.1    Akahori, H.2    Takahashi, K.3
  • 21
    • 0344530245 scopus 로고    scopus 로고
    • New TPO treatment schedules of increased safety and ef?cacy: Pre-clinical validation of a thrombopoiesis simulation model
    • Skomorovski K, Harpak H, Ianovski A, et al. New TPO treatment schedules of increased safety and ef?cacy: pre-clinical validation of a thrombopoiesis simulation model. Br J Haematol. 2003;123:683-691.
    • (2003) Br J Haematol , vol.123 , pp. 683-691
    • Skomorovski, K.1    Harpak, H.2    Ianovski, A.3
  • 22
    • 0029151323 scopus 로고
    • Thrombopoietin induces megakaryocyte differentiation in hematopoietic progenitor FDC-P2 cells
    • Nagata Y, Nagahisa H, Aida Y, et al. Thrombopoietin induces megakaryocyte differentiation in hematopoietic progenitor FDC-P2 cells. J Biol Chem. 1995;270:19673-19675.
    • (1995) J Biol Chem , vol.270 , pp. 19673-19675
    • Nagata, Y.1    Nagahisa, H.2    Aida, Y.3
  • 23
    • 0030950319 scopus 로고    scopus 로고
    • Serum thrombopoietin level is not regulated by transcription but by the total counts of both megakaryocytes and platelets during thrombocytopenia and thrombocytosis
    • Nagata Y, Shozaki Y, Nagahisa H, et al. Serum thrombopoietin level is not regulated by transcription but by the total counts of both megakaryocytes and platelets during thrombocytopenia and thrombocytosis. Thromb Haemost. 1997;77:808-814.
    • (1997) Thromb Haemost , vol.77 , pp. 808-814
    • Nagata, Y.1    Shozaki, Y.2    Nagahisa, H.3
  • 24
    • 36549047972 scopus 로고    scopus 로고
    • Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C
    • McHutchinson JG, Dusheiko G, Shiffman ML, et al. Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C. N Engl J Med. 2007;357:2227-2236.
    • (2007) N Engl J Med , vol.357 , pp. 2227-2236
    • McHutchinson, J.G.1    Dusheiko, G.2    Shiffman, M.L.3
  • 25
    • 0023425909 scopus 로고
    • A morphological study of the early stages of hepatic ?brosis induced by low doses of dimethylni-trosamine in the rat
    • Je'ze'quel AM, Mancini R, Rinaldesi ML, et al. A morphological study of the early stages of hepatic ?brosis induced by low doses of dimethylni-trosamine in the rat. J Hepatol. 1987;5:174-181.
    • (1987) J Hepatol , vol.5 , pp. 174-181
    • Je'ze'quel, A.M.1    Mancini, R.2    Rinaldesi, M.L.3
  • 26
    • 0032004585 scopus 로고    scopus 로고
    • Perioperative continuous hepatocytes growth factor supply prevents postoperative liver failure in rats with liver cirrhosis
    • Kaido T, Seto S, Yamaoka S, et al. Perioperative continuous hepatocytes growth factor supply prevents postoperative liver failure in rats with liver cirrhosis. J Surg Res. 1998;74:173-179.
    • (1998) J Surg Res , vol.74 , pp. 173-179
    • Kaido, T.1    Seto, S.2    Yamaoka, S.3
  • 27
    • 0029053707 scopus 로고
    • Perspectives in the treatment of liver ?brosis
    • Mavier P, Mallat A. Perspectives in the treatment of liver ?brosis. J Hepatol. 1995;22(suppl 2):111-115.
    • (1995) J Hepatol , vol.22 , Issue.SUPPL. 2 , pp. 111-115
    • Mavier, P.1    Mallat, A.2
  • 28
    • 0034093877 scopus 로고    scopus 로고
    • Differential expression of apoptosis-associated genes post-hepatectomy in cirrhotic vs. normal rats
    • Masson S, Scotte M, Garnier S, et al. Differential expression of apoptosis-associated genes post-hepatectomy in cirrhotic vs. normal rats. Apoptosis. 2000;5:173-179.
    • (2000) Apoptosis , vol.5 , pp. 173-179
    • Masson, S.1    Scotte, M.2    Garnier, S.3
  • 29
    • 0030857949 scopus 로고    scopus 로고
    • Stimulation of liver regeneration and function after partial hepatectomy in cirrhotic rats by continuous infusion of recombinant human hepatocytes growth factor
    • Kaibori M, Kwon AH, Nakagawa M, et al. Stimulation of liver regeneration and function after partial hepatectomy in cirrhotic rats by continuous infusion of recombinant human hepatocytes growth factor. J Hepatol. 1997;27:381-390.
    • (1997) J Hepatol , vol.27 , pp. 381-390
    • Kaibori, M.1    Kwon, A.H.2    Nakagawa, M.3
  • 30
    • 0036708283 scopus 로고    scopus 로고
    • Halofuginone, a collagen type I inhibitor improves liver regeneration in cirrhotic rats
    • Spira G, Mawasi N, Paizi M, et al. Halofuginone, a collagen type I inhibitor improves liver regeneration in cirrhotic rats. J Hepatol. 2002; 37:331-339.
    • (2002) J Hepatol , vol.37 , pp. 331-339
    • Spira, G.1    Mawasi, N.2    Paizi, M.3
  • 31
    • 29744452649 scopus 로고    scopus 로고
    • Administration of rhHGF- activator via portal vein stimulates the regeneration of cirrhotic liver after partial hepatectomy in rats
    • Yanagida H, Kaibori M, Hijikawa T, et al. Administration of rhHGF- activator via portal vein stimulates the regeneration of cirrhotic liver after partial hepatectomy in rats. J Surg Res. 2006;130:38-44.
    • (2006) J Surg Res , vol.130 , pp. 38-44
    • Yanagida, H.1    Kaibori, M.2    Hijikawa, T.3
  • 32
    • 0031035555 scopus 로고    scopus 로고
    • Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization
    • Sungaran R, Markovic B, Chong BH. Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization. Blood. 1997;89:101-107.
    • (1997) Blood , vol.89 , pp. 101-107
    • Sungaran, R.1    Markovic, B.2    Chong, B.H.3
  • 33
    • 0034958430 scopus 로고    scopus 로고
    • The role of the liver in the production of thrombopoietin compared with erythropoietin
    • Jelkmann W. The role of the liver in the production of thrombopoietin compared with erythropoietin. Eur J Gastroenterol Hepatol. 2001;13: 791-801.
    • (2001) Eur J Gastroenterol Hepatol , vol.13 , pp. 791-801
    • Jelkmann, W.1
  • 34
    • 0030818789 scopus 로고    scopus 로고
    • Thrombopoietin levels in patients with cirrhosis before and after orthopic liver transplantation
    • Martin TG III, Somberg KA, Mebg YG, et al. Thrombopoietin levels in patients with cirrhosis before and after orthopic liver transplantation. Ann Intern Med. 1997;127:285-288.
    • (1997) Ann Intern Med , vol.127 , pp. 285-288
    • Martin III, T.G.1    Somberg, K.A.2    Mebg, Y.G.3
  • 35
    • 0031720994 scopus 로고    scopus 로고
    • Reduced expression of throm-bopoietin is involved in thrombocytopenia in human and rat liver cirrhosis
    • Ishikawa T, Ichida T, Matsuda Y, et al. Reduced expression of throm-bopoietin is involved in thrombocytopenia in human and rat liver cirrhosis. J Gastroenterol Hepatol. 1998;13:907-913.
    • (1998) J Gastroenterol Hepatol , vol.13 , pp. 907-913
    • Ishikawa, T.1    Ichida, T.2    Matsuda, Y.3
  • 36
    • 0032995027 scopus 로고    scopus 로고
    • Hepatic thrombopoietin mRNA levels in acute and chronic liver failure of childhood
    • Wolber EM, Ganschow R, Burdelski M, et al. Hepatic thrombopoietin mRNA levels in acute and chronic liver failure of childhood. Hepatology. 1999;29:1739-1742.
    • (1999) Hepatology , vol.29 , pp. 1739-1742
    • Wolber, E.M.1    Ganschow, R.2    Burdelski, M.3
  • 37
    • 39849110575 scopus 로고    scopus 로고
    • Thrombopoietin is a growth factor for rat hepatic progenitors
    • Schmelzer E, Deiwick A, Bruns H, et al. Thrombopoietin is a growth factor for rat hepatic progenitors. Eur J Gastroenterol Hepatol. 2008; 20:209-216.
    • (2008) Eur J Gastroenterol Hepatol , vol.20 , pp. 209-216
    • Schmelzer, E.1    Deiwick, A.2    Bruns, H.3
  • 38
    • 33847747457 scopus 로고    scopus 로고
    • Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice
    • Nocito A, Georgiev P, Dahm F, et al. Platelets and platelet-derived serotonin promote tissue repair after normothermic hepatic ischemia in mice. Hepatology. 2007;45:369-376.
    • (2007) Hepatology , vol.45 , pp. 369-376
    • Nocito, A.1    Georgiev, P.2    Dahm, F.3
  • 39
    • 0033515099 scopus 로고    scopus 로고
    • Blockade of type beta transforming growth factor signaling prevents liver ?brosis and dysfunction in the rat
    • Qi Z, Atsuchi N, Ooshima A, et al. Blockade of type beta transforming growth factor signaling prevents liver ?brosis and dysfunction in the rat. Proc Natl Acad Sci U S A. 1999;96:2345-2349.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 2345-2349
    • Qi, Z.1    Atsuchi, N.2    Ooshima, A.3
  • 40
    • 0033854016 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor beta prevents progression of liver ?brosis and enhances hepatocytes regeneration in dimethylnitrosamine-treated rats
    • Nakamura T, Sakata R, Ueno T, et al. Inhibition of transforming growth factor beta prevents progression of liver ?brosis and enhances hepatocytes regeneration in dimethylnitrosamine-treated rats. Hepatology. 2000;32:247-255.
    • (2000) Hepatology , vol.32 , pp. 247-255
    • Nakamura, T.1    Sakata, R.2    Ueno, T.3
  • 41
    • 0032903634 scopus 로고    scopus 로고
    • Hepatocyte growth factor gene therapy of liver cirrhosis in rats
    • Ueki T, Kaneda Y, Tsutsui H, et al. Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med. 1999;5:226-230.
    • (1999) Nat Med , vol.5 , pp. 226-230
    • Ueki, T.1    Kaneda, Y.2    Tsutsui, H.3
  • 42
    • 0034813705 scopus 로고    scopus 로고
    • Adenosine reverses a preestablished CCl4-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats
    • Hernandez-Munoz R, Diaz-Munoz M, Suarez-Cuenca JA, et al. Adenosine reverses a preestablished CCl4-induced micronodular cirrhosis through enhancing collagenolytic activity and stimulating hepatocyte cell proliferation in rats. Hepatology. 2001;34:677-687.
    • (2001) Hepatology , vol.34 , pp. 677-687
    • Hernandez-Munoz, R.1    Diaz-Munoz, M.2    Suarez-Cuenca, J.A.3
  • 43
    • 10644226862 scopus 로고    scopus 로고
    • Transdifferentiation of bone marrow cells reduces CCl4-induced liver ?brosis in mice
    • Sakaida I, Terai S, Yamamoto N, et al. Transdifferentiation of bone marrow cells reduces CCl4-induced liver ?brosis in mice. Hepatology. 2004;40:1304-1311.
    • (2004) Hepatology , vol.40 , pp. 1304-1311
    • Sakaida, I.1    Terai, S.2    Yamamoto, N.3
  • 44
    • 9144236848 scopus 로고    scopus 로고
    • A subpopulation of bone marrow cells depleted by a novel antibody, anti Liv8, is useful for cell therapy to repair damaged liver
    • Yamamoto N, Terai S, Ohata S, et al. A subpopulation of bone marrow cells depleted by a novel antibody, anti Liv8, is useful for cell therapy to repair damaged liver. Biochem Biophys Res Commun. 2004;313:1110-1118.
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 1110-1118
    • Yamamoto, N.1    Terai, S.2    Ohata, S.3
  • 45
    • 34447092409 scopus 로고    scopus 로고
    • Signi?cance and therapeutic potential of endothelial progenitor cell transplantation in a cirrhotic liver rat model
    • Nakamura T, Torimura T, Sakamoto M, et al. Signi?cance and therapeutic potential of endothelial progenitor cell transplantation in a cirrhotic liver rat model. Gastroenterology. 2007;133:91-107.
    • (2007) Gastroenterology , vol.133 , pp. 91-107
    • Nakamura, T.1    Torimura, T.2    Sakamoto, M.3
  • 46
    • 23944477349 scopus 로고    scopus 로고
    • Dual effects of adenovirus-mediated thrombopoietin gene transfer on hepatic oval cell proliferation and platelet counts
    • Ichiba M, Shimomura T, Shiota G, et al. Dual effects of adenovirus-mediated thrombopoietin gene transfer on hepatic oval cell proliferation and platelet counts. Biochem Biophys Res Commun. 2005;335:723-729.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 723-729
    • Ichiba, M.1    Shimomura, T.2    Shiota, G.3
  • 47
    • 36049015087 scopus 로고    scopus 로고
    • Platelet interaction with progenitor cells: Potential implications for regenerative medicine
    • Stellos K, Gawaz M. Platelet interaction with progenitor cells: potential implications for regenerative medicine. Thromb Haemost. 2007;98: 922-929.
    • (2007) Thromb Haemost , vol.98 , pp. 922-929
    • Stellos, K.1    Gawaz, M.2


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