Impact of tight glucose control on postoperative infection rates and wound healing in cardiac surgery patients

Journal of Wound, Ostomy and Continence Nursing

Volumn 35, Issue 4, 2008, Pages 397-404

  Patel, Karin L ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT;

ARTICLE; BLOOD; DIABETIC ANGIOPATHY; GLUCOSE BLOOD LEVEL; HEART DISEASE; HEART SURGERY; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; POSTOPERATIVE COMPLICATION; STANDARD; SURGICAL INFECTION; WOUND HEALING;

BLOOD GLUCOSE; CARDIAC SURGICAL PROCEDURES; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; HEART DISEASES; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; POSTOPERATIVE COMPLICATIONS; SURGICAL WOUND INFECTION; WOUND HEALING;

EID: 56149110359     PISSN: 10715754     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.WON.0000326659.47637.d0     Document Type: Article

References (46)

1. Bradley S, Crabtree S. Major medical associations call for better blood glucose management in hospitalized patients [press release]. Washington, DC: American Association of Clinical Endocrinologists; 2006.
2. Streeter NB. Considerations in prevention of surgical site infections following cardiac surgery: when your patient is diabetic. J Cardiovasc Nurs. 2006;21(3):E14-E20.
3. McCance K, Heuther S. Pathophysiology: The Biologic Basis for Disease in Adults & Children. 4th ed. St Louis, MO: Mosby Inc; 2002.
4. Greenberg AS. The expanding scope of the metabolic syndrome and implications for the management of cardiovascular risk in the type 2 diabetes with particular focus on the emerging role of the thiazolidinediones. J Diabetes Complications. 2003;17(4):218-228.
5. UK Prospective DM Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet. 1998;352:854-865.
6. Kirchner LM, Meerbaum SO, Gruber BS, et al. Effects of vascular endothelial growth factor on wound closure rates in the genetically diabetic mouse model. Wound Repair Regen. 2003;11(2): 127-131.
7. Nortcliffe SA, Buggy DJ. Implications of anesthesia for infection and wound healing. Int Anesthesiol Clin. 2003;41(1):31-64.
8. Joshi N, Caputo GM, Weitekamp MR, Karchmer AW. Infections in patients with diabetes mellitus. N Engl J Med. 1999;341(25):1906-1912.
9. Lyons TJ, Li W, Wells-Knecht MC, Jokl R. Toxicity of mildly modified low-density lipoproteins to cultured retinal capillary endothelial cells and pericytes. Diabetes. 1994;43(9):1090-1095.
10. Panza JA. Endothelial dysfunction in essential hypertension. Clin Cardiol. 1997;20(11)(suppl 2):II26-II33.
11. Title L, Cummings PM, Giddens K, Nassar BA. Oral glucose loading acutely attenuates endothelium-dependent vasodilation in healthy adults without diabetes: an effect prevented by vitamins C and E. J Am Coll Cardiol. 2000;36:2185-2191.
12. Pueyo ME, Gonzalez W, Nicoletti A, Savoie F, Arnal JF, Michel JB. Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor kappaB activation induced by intracellular oxidative stress. Arterioscler Thromb Vasc Biol. 2000;20(3):645-651.
13. Quinn MT, Parthasarathy S, Fong LG, Steinberg D. Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc Natl Acad Sci U S A. 1987;84(9):2995-2998.
14. Watanabe T, Pakala R, Katagiri T, Benedict CR. Mildly oxidized low-density lipoprotein acts synergistically with angiotensin II in inducing vascular smooth muscle cell proliferation. J Hypertens. 2001;19(6):1065-1073.
15. Shapiro J, Fetherston G, Richardson G. Prevention of infection in a patient with chronic idiopathic neutropenia undergoing coronary bypass surgery with peri-operative G-CSF. ANZ J Surg. 1996;66(12):841-842.
16. King L. Impaired wound healing in patients with diabetes. Nurs Stand. 2001;15(38):39-45.
17. Greif R, Akca O, Horn EP, Kurz A, Sessler DI. Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection. Outcomes Research Group. N Engl J Med. 2000; 342(3):161-167.
18. Wolfe RR, Allsop JR, Burke JF. Glucose metabolism in man: responses to intravenous glucose infusion. Metabolism. 1979; 28(3):210-220.
19. Wolfe RR, Herndon DN, Jahoor F, Miyoshi H, Wolfe M. Effect of severe burn injury on substrate cycling by glucose and fatty acids. N Engl J Med. 1987;317(7):403-408.
20. Shangraw RE, Jahoor F, Miyoshi H, et al. Differentiation between septic and postburn insulin resistance. Metabolism. 1989;38(10):983-989.
21. Golden SH, Peart-Vigilance C, Kao WH, Brancati FL. Perioperative glycemic control and the risk of infectious complications in a cohort of adults with diabetes. Diabetes Care. 1999;22(9):1408-1414.
22. Turina M, Miller FN, Tucker CF, Polk HC. Short-term hyperglycemia in surgical patients and a study of related cellular mechanisms. Ann Surg. 2006;243(6):845-851, discussion 851-1843
23. Sommerfield AJ, Deary IJ, Frier BM. Acute hyperglycemia alters mood state and impairs cognitive performance in people with type 2 diabetes. Diabetes Care. 2004;27(10): 2335-2340.
24. Mizock BA. Alterations in carbohydrate metabolism during stress: a review of the literature. Am J Med. 1995;98(1): 75-84.
25. McCowen KC, Malhotra A, Bistrian BR. Stress-induced hyperglycemia. Crit Care Clin. 2001;17(1):107-124.
26. Fietsam R Jr, Bassett J, Glover JL. Complications of coronary artery surgery in diabetic patients. Am Surg. 1991;57(9): 551-557.
27. Scott JF, Robinson GM, French JM, O'Connell JE, Alberti KG, Gray CS. Glucose potassium insulin infusions in the treatment of acute stroke patients with mild to moderate hyperglycemia: the Glucose Insulin in Stroke Trial (GIST). Stroke. 1999;30(4): 793-799.
28. Van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in the critically ill patients. N Engl J Med. 2001; 345(19):1359-1367.
29. Masharani U, Karam JH, German MS. Pancreatic hormones and diabetes mellitus: surgery in the diabetic patient. Basic & Clinical Endocrinology. 7th ed. San Francisco, CA: McGraw-Hill; 2001:658-746.
30. Lorenz RA, Lorenz RM, Codd JE. Perioperative blood glucose control during adult coronary artery bypass surgery. AORN J. 2005;81(1):126-144, 147-150; quiz 151-1124
31. Golightly LK, Jones MA, Hamamura DH, Stolpman NM, McDermott MT. Management of diabetes mellitus in hospitalized patients: efficiency and effectiveness of sliding-scale insulin therapy. Pharmacotherapy. 2006;26(10):1421-1432.
32. Schricker T, Lattermann R, Fiset P, Wykes L, Carli F. Integrated analysis of protein and glucose metabolism during surgery: effects of anesthesia. J Appl Physiol. 2001;91(6):2523-2530.
33. Khaodhiar L, McCowen K, Bistrian B. Perioperative hyperglycemia, infection or risk? Curr Opin Clin Nutr Metab Care. 1999;2(1):79-82.
34. Kohl B, Deutschman CS. The inflammatory response to surgery and trauma [The surgical patient]. Curr Opin Crit Care. 2006; 12(4):325-332.
35. Gandhi GY, Nuttall GA, Abel MD, et al. Intraoperative hyperglycemia and perioperative outcomes in cardiac surgery patients. Mayo Clin Proc. 2005;80(7):862-866.
36. Ouattara A, Lecomte P, Le Manach Y, et al. Poor intraoperative blood glucose control is associated with a worsened hospital outcome after cardiac surgery in diabetic patients. Anesthesiology. 2005;103(4):687-694.
37. Hruska LA, Smith JM, Hendy MP, Fritz VL, McAdams S. Continuous insulin infusion reduces infectious complications in diabetics following coronary surgery. J Card Surg. 2005; 20(5):403-407.
38. Zerr KJ, Furnary AP, Grunkemeier GL, Bookin S, Kanhere V, Starr A. Glucose control lowers the risk of wound infection in diabetics after open heart operations. Ann Thorac Surg. 1997; 63(2):356-361.
39. Furnary AP, Zerr KJ, Grunkemeier GL, Starr A. Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures. Ann Thorac Surg. 1999;67(2):352-360, discussion 360-1352
40. Boucher J, Swift CS, Franz MJ, Kulkarni K, Schafer RG, Pritchett E, et al. Inpatient management of diabetes and hyperglycemia: implications for nutrition practice and the food and nutrition professional. J Am Diet Assoc. 2007;107(1):105-110.
41. American Diabetes Association. Standards of medical care in diabetes- 2007. Diabetes Care. 2006;29(suppl 1):S29.
42. Lazar HL, Chipkin SR, Fitzgerald CA, Bao Y, Cabral H, Apstein CS. Tight glycemic control in diabetic coronary artery bypass graft patients improves perioperative outcomes and decreases recurrent ischemic events. Circulation. 2004;109(12):1497-1502.
43. Zimmerman CR, Miynarek ME, Jordan JA, Rajda CA, Horst HM. An insulin infusion protocol in critically ill cardiothoracic surgery patients. Ann Pharmacother. 2004;38(7/8):1123-1129.
44. Furnary AP, Gao G, Grunkemeier GL, et al. Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2003;125(5):1007-1021.
45. Swenne CL, Lindholm C, Borowiec J, Schnell AE, Carlsson M. Peri-operative glucose control and development of surgical wound infections in patients undergoing coronary artery bypass graft. J Hosp Infect. 2005;61(3):201-212.
46. Krinsley JS. Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clin Proc. 2002;79(8):992-1000.