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Volumn 5, Issue 10 SUPPL. A, 2008, Pages 1-4

Evaluating the addition of AMG 655 to mFOLFOX6/bevacizumab in metastatic colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

AMG 655; BEVACIZUMAB; DEATH RECEPTOR 5; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; IRINOTECAN; MONOCLONAL ANTIBODY; OXALIPLATIN; PLACEBO; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

EID: 56149104587     PISSN: 15485315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey
Times cited : (1)

References (9)
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    • American Cancer Society. Cancer Facts & Figures 2008. Atlanta, Ga: American Cancer Society; 2008. Available at: http://www.cancer.org/downloads/ STT/2008CAFFfinalsecured.pdf. Accessed September 16, 2008.
    • (2008) Cancer Facts & Figures 2008
  • 2
    • 2542563257 scopus 로고    scopus 로고
    • Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: Who benefits and by how much?
    • Gill S, Loprinri CL, Sargent DJ, et al. Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much? J Clin Oncol 2004;22:1797-1806.
    • (2004) J Clin Oncol , vol.22 , pp. 1797-1806
    • Gill, S.1    Loprinri, C.L.2    Sargent, D.J.3
  • 4
    • 56149086096 scopus 로고    scopus 로고
    • NCI Drug Dictionary
    • US Institutes of Health. Available at:, Accessed September 16, 2008
    • National Cancer Institute. NCI Drug Dictionary. Anti-TRAIL receptor 2 monoclonal antibody AMG 655. US Institutes of Health. Available at: http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=573083. Accessed September 16, 2008.
    • Anti-TRAIL receptor 2 monoclonal antibody AMG , vol.655
  • 5
    • 3342894130 scopus 로고    scopus 로고
    • Targeting death receptors in cancer with Apo2L/TRAIL
    • Kelley SK, Ashkenazi A. Targeting death receptors in cancer with Apo2L/TRAIL. Curr Opin Pharmacol 2004;4:333-339.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 333-339
    • Kelley, S.K.1    Ashkenazi, A.2
  • 6
    • 28544443984 scopus 로고    scopus 로고
    • Promoting apoptosis as a drug strategy for cancer drug discovery
    • Fesik SW. Promoting apoptosis as a drug strategy for cancer drug discovery. Nat Rev Cancer 2005;5:876-885.
    • (2005) Nat Rev Cancer , vol.5 , pp. 876-885
    • Fesik, S.W.1
  • 7
    • 56149103546 scopus 로고    scopus 로고
    • AMG 655, a fully human agonistic antibody against death receptor 5, enhances the anti-tumor activity of gemcitabine in MiaPaCa2/T2, a pancreatic cancer model
    • Presented at the April 12-16, San Diego, Calif. Abstract 3999
    • Kaplan-Lefko P, Bush T, Belmontes B, et al. AMG 655, a fully human agonistic antibody against death receptor 5, enhances the anti-tumor activity of gemcitabine in MiaPaCa2/T2, a pancreatic cancer model. Presented at the 2008 Annual Meeting of the American Association for Cancer Research; April 12-16, 2008; San Diego, Calif. Abstract 3999.
    • (2008) 2008 Annual Meeting of the American Association for Cancer Research
    • Kaplan-Lefko, P.1    Bush, T.2    Belmontes, B.3
  • 8
    • 56149101676 scopus 로고    scopus 로고
    • Combined treatment of angiopoietin and VEGF pathway antagonists enhances antitumor activity in preclinical models of colon carcinoma
    • Presented at the April 12-16, San Diego, Calif. Abstract 1113
    • Coxon A, Rex K, Sun J-R, et al. Combined treatment of angiopoietin and VEGF pathway antagonists enhances antitumor activity in preclinical models of colon carcinoma. Presented at the 2008 Annual Meeting of the American Association for Cancer Research; April 12-16, 2008; San Diego, Calif. Abstract 1113.
    • (2008) 2008 Annual Meeting of the American Association for Cancer Research
    • Coxon, A.1    Rex, K.2    Sun, J.-R.3
  • 9
    • 56149108834 scopus 로고    scopus 로고
    • LoRusso P, Hong D, Heath E, et al. First-in-human study of AMG 655, a pro-apoptotic TRAIL receptor-2 agonist, in adult patients with advanced solid tumors. J Clin Oncol 2007;25(18S):3534.
    • LoRusso P, Hong D, Heath E, et al. First-in-human study of AMG 655, a pro-apoptotic TRAIL receptor-2 agonist, in adult patients with advanced solid tumors. J Clin Oncol 2007;25(18S):3534.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.