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Volumn 5, Issue 5, 2008, Pages 457-469

The re-emerging concept of personalized healthcare

Author keywords

ADR; Adverse drug reaction; BRC1 2; CYP2C9; Genetic testing Her2 NEu; Personalized healthcare; Personalized medicine; Pharmacogenomics; SNP; VKORC1

Indexed keywords

BIOLOGICAL MARKER; CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMATINIB; TRASTUZUMAB; WARFARIN;

EID: 56149103903     PISSN: 17410541     EISSN: 1744828X     Source Type: Journal    
DOI: 10.2217/17410541.5.5.457     Document Type: Review
Times cited : (5)

References (27)
  • 1
    • 33947312462 scopus 로고    scopus 로고
    • Health spending projections through 2016: Modest changes obscure part D's impact
    • Poisal JA, Truffer C, Smith S et al.: Health spending projections through 2016: modest changes obscure part D's impact. Health Aff. (Millwood) 26(2). W242-W253 (2007).
    • (2007) Health Aff. (Millwood) , vol.26 , Issue.2
    • Poisal, J.A.1    Truffer, C.2    Smith, S.3
  • 2
    • 33847370869 scopus 로고    scopus 로고
    • WHO, Geneva, Switzerland 2000
    • The World Health Report 2000. WHO, Geneva, Switzerland (2000).
    • The World Health
  • 3
    • 38349190243 scopus 로고    scopus 로고
    • MicroRNAs modulate the chemosensitivity of tumor cells
    • Blower PE, Chung JH, Verducci JS et al.: MicroRNAs modulate the chemosensitivity of tumor cells. Mol. Cancer Ther. 7(1), 1-9 (2008).
    • (2008) Mol. Cancer Ther , vol.7 , Issue.1 , pp. 1-9
    • Blower, P.E.1    Chung, J.H.2    Verducci, J.S.3
  • 5
    • 23644437525 scopus 로고    scopus 로고
    • Common VKORC1 and GGCX polymorphisms associated with warfarin dose
    • Wadelius, M, Chen LY, Downes K et al.: Common VKORC1 and GGCX polymorphisms associated with warfarin dose. Pharmacogenomics J. 5, 262-270 (2005).
    • (2005) Pharmacogenomics J , vol.5 , pp. 262-270
    • Wadelius, M.1    Chen, L.Y.2    Downes, K.3
  • 6
    • 0037374422 scopus 로고    scopus 로고
    • Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients
    • Takahashi, H, Wilkinson GR, Caraco Y et al.: Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients. Clin. Pharmacol. Ther. 73, 253-263 (2003).
    • (2003) Clin. Pharmacol. Ther , vol.73 , pp. 253-263
    • Takahashi, H.1    Wilkinson, G.R.2    Caraco, Y.3
  • 7
    • 0027257511 scopus 로고
    • Anticoagulant-related bleeding: Clinical epidemiology, prediction, and prevention
    • Landefeld, CS, Beyth RJ: Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention. Am. J. Med. 95, 315-328 (1993).
    • (1993) Am. J. Med , vol.95 , pp. 315-328
    • Landefeld, C.S.1    Beyth, R.J.2
  • 8
    • 47949086046 scopus 로고    scopus 로고
    • Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
    • Epub ahead of print
    • Gage B, Eby C, Johnson J, et al.: Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin. Pharmacol. Ther. (2008) (Epub ahead of print).
    • (2008) Clin. Pharmacol. Ther
    • Gage, B.1    Eby, C.2    Johnson, J.3
  • 9
    • 34247215617 scopus 로고    scopus 로고
    • Warfarin response and vitamin K epoxide reductase complex 1 in African Americans and Caucasians
    • 207
    • Schelleman H, Chen Z, Kealey C et al.: Warfarin response and vitamin K epoxide reductase complex 1 in African Americans and Caucasians. Clin. Pharmacol. Ther. 81(5), 742-747 (207).
    • Clin. Pharmacol. Ther , vol.81 , Issue.5 , pp. 742-747
    • Schelleman, H.1    Chen, Z.2    Kealey, C.3
  • 10
    • 21144448879 scopus 로고    scopus 로고
    • Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
    • Rieder MJ, Reiner AP, Gage BF et al.: Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N. Engl. J. Med. 352, 2285-2293 (2005).
    • (2005) N. Engl. J. Med , vol.352 , pp. 2285-2293
    • Rieder, M.J.1    Reiner, A.P.2    Gage, B.F.3
  • 11
    • 0037012465 scopus 로고    scopus 로고
    • Association between CYP2C9 genetic variants and anticoagutation-related outcomes during warfarin therapy
    • Higashi MK, Veenstra DL, Kondo LM et al.: Association between CYP2C9 genetic variants and anticoagutation-related outcomes during warfarin therapy, JAMA 287, 1690-1698 (2002).
    • (2002) JAMA , vol.287 , pp. 1690-1698
    • Higashi, M.K.1    Veenstra, D.L.2    Kondo, L.M.3
  • 12
    • 39449109003 scopus 로고    scopus 로고
    • A rapid-ACCE review of CYP2C9 and VKORC1 alieles testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding
    • McClain, MR, Palomaki GE, Piper M, Haddow JE: A rapid-ACCE review of CYP2C9 and VKORC1 alieles testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding. Genet. Med. 10, 89-98 (2008).
    • (2008) Genet. Med , vol.10 , pp. 89-98
    • McClain, M.R.1    Palomaki, G.E.2    Piper, M.3    Haddow, J.E.4
  • 13
    • 0024316072 scopus 로고
    • Major bleeding in outpatients treated with warfarin: Incidence and prediction by factors known at the start of outpatient therapy
    • Landefeld CS, Goldman L: Major bleeding in outpatients treated with warfarin: incidence and prediction by factors known at the start of outpatient therapy. Am. J. Med. 87, 144-152 (1989).
    • (1989) Am. J. Med , vol.87 , pp. 144-152
    • Landefeld, C.S.1    Goldman, L.2
  • 14
    • 39449086981 scopus 로고    scopus 로고
    • CYP2C9 genotype-guided warfarin prescribing enhances the efficacy and safety of anticoagulation: A prospective randomized conirolled study
    • Caraco Y, Blotnick S, Muszkat M: CYP2C9 genotype-guided warfarin prescribing enhances the efficacy and safety of anticoagulation: a prospective randomized conirolled study. Clin. Pharmacol. Ther. 83, 460-470 (2008).
    • (2008) Clin. Pharmacol. Ther , vol.83 , pp. 460-470
    • Caraco, Y.1    Blotnick, S.2    Muszkat, M.3
  • 15
    • 40449120615 scopus 로고    scopus 로고
    • Genetic determinants of response to warfarin during initial anticoagulation
    • Schwarz UI, Ritchie MD. Bradford Y et al.: Genetic determinants of response to warfarin during initial anticoagulation. N. Engl. J. Med. 358. 999-1008 (2008).
    • (2008) N. Engl. J. Med , vol.358 , pp. 999-1008
    • Schwarz, U.I.1    Ritchie, M.D.2    Bradford, Y.3
  • 16
    • 38849181014 scopus 로고    scopus 로고
    • Genetic testing for warfarin dosing? Not yet ready for prime time
    • Bussey HI, Wittkowsky AK, Hylek EM, Walker MB: Genetic testing for warfarin dosing? Not yet ready for prime time. Pharmacotherapy 28(2), 141-143 (2008).
    • (2008) Pharmacotherapy , vol.28 , Issue.2 , pp. 141-143
    • Bussey, H.I.1    Wittkowsky, A.K.2    Hylek, E.M.3    Walker, M.B.4
  • 17
    • 38049181030 scopus 로고    scopus 로고
    • Pharmacogenetics of warfarin: Regulatory, scientific, and clinical issues
    • Gage BF, Lesko LJ: Pharmacogenetics of warfarin: regulatory, scientific, and clinical issues. J. Thromb. Thrombolysis 25(1), 45-51 (2008).
    • (2008) J. Thromb. Thrombolysis , vol.25 , Issue.1 , pp. 45-51
    • Gage, B.F.1    Lesko, L.J.2
  • 18
    • 40449124033 scopus 로고    scopus 로고
    • Pharmacogenomics - ready for prime time?
    • Shurin SB, Nabel EG: Pharmacogenomics - ready for prime time? N. Engl. J. Med. 358(10), 1061-1063 (2008).
    • (2008) N. Engl. J. Med , vol.358 , Issue.10 , pp. 1061-1063
    • Shurin, S.B.1    Nabel, E.G.2
  • 19
    • 51649084617 scopus 로고    scopus 로고
    • Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement
    • Wang D, Chen H. Momary KM, Cavallari LH, Johnson JA, Sadee W: Regulatory polymorphism in vitamin K epoxide reductase complex subunit 1 (VKORC1) affects gene expression and warfarin dose requirement. Blood 112(4), 1013-1021 (2008).
    • (2008) Blood , vol.112 , Issue.4 , pp. 1013-1021
    • Wang, D.1    Chen, H.2    Momary, K.M.3    Cavallari, L.H.4    Johnson, J.A.5    Sadee, W.6
  • 20
    • 42149188553 scopus 로고    scopus 로고
    • CYP4F2 genetic variant alters required warfarin dose
    • Caldwell MD, Awad T, Johnson A et al.: CYP4F2 genetic variant alters required warfarin dose. Blood 111(8), 4106-4112 (2008).
    • (2008) Blood , vol.111 , Issue.8 , pp. 4106-4112
    • Caldwell, M.D.1    Awad, T.2    Johnson, A.3
  • 21
    • 0035861049 scopus 로고    scopus 로고
    • Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review
    • Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W: Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review. JAMA 286, 2270-2279 (2001).
    • (2001) JAMA , vol.286 , pp. 2270-2279
    • Phillips, K.A.1    Veenstra, D.L.2    Oren, E.3    Lee, J.K.4    Sadee, W.5
  • 22
    • 38449111028 scopus 로고    scopus 로고
    • E1-Deiry WS: P53, BRCA1 and breast cancer chemoresistance
    • Scata KA, E1-Deiry WS: p53, BRCA1 and breast cancer chemoresistance. Adv Exp. Med. Biol. 608, 70-86 (2007).
    • (2007) Adv Exp. Med. Biol , vol.608 , pp. 70-86
    • Scata, K.A.1
  • 23
    • 33644848237 scopus 로고    scopus 로고
    • Trastuzumab after primary treatment for early stage HER2-positive breast cancer reduces recurrence
    • Dent R, Clemons M: Trastuzumab after primary treatment for early stage HER2-positive breast cancer reduces recurrence. Cancer Treat. Rev. 32, 144-148 (2006).
    • (2006) Cancer Treat. Rev , vol.32 , pp. 144-148
    • Dent, R.1    Clemons, M.2
  • 24
    • 33845444046 scopus 로고    scopus 로고
    • Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
    • Druker BJ, Guilhot F, O'Brien SG et al.: Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N. Engl. J. Med. 355, 2408-2417 (2006).
    • (2006) N. Engl. J. Med , vol.355 , pp. 2408-2417
    • Druker, B.J.1    Guilhot, F.2    O'Brien, S.G.3
  • 25
    • 4143142117 scopus 로고    scopus 로고
    • MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
    • Calin GA, Liu CG, Sevignani C et al.: MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl. Acad. Sci. USA 101, 11755-11760 (2004).
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 11755-11760
    • Calin, G.A.1    Liu, C.G.2    Sevignani, C.3
  • 26
    • 30044436911 scopus 로고    scopus 로고
    • The role of microRNA genes in papillary thyroid carcinoma
    • He H. Jazdzewski K, Li W et al.: The role of microRNA genes in papillary thyroid carcinoma. Proc. Natal. Acad. Sci. USA 102, 19075-19080 (2005).
    • (2005) Proc. Natal. Acad. Sci. USA , vol.102 , pp. 19075-19080
    • He, H.1    Jazdzewski, K.2    Li, W.3
  • 27
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska EA et al.: MicroRNA expression profiles classify human cancers. Nature 435. 834-838 (2005).
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3


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