Liver function critically determines serum retinol-binding protein 4 (RBP4) levels in patients with chronic liver disease and cirrhosis

Hepatology

Volumn 48, Issue 5, 2008, Pages 1724-1725

  Tacke, Frank ^a   Weiskirchen, Ralf ^a   Trautwen, Christian ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BLOOD CLOTTING FACTOR 7; CHOLINESTERASE; MESSENGER RNA; PROTHROMBIN; RETINOL BINDING PROTEIN 4; BIOLOGICAL MARKER; PLASMA RETINOL BINDING PROTEIN; RBP4 PROTEIN, HUMAN;

CHRONIC LIVER DISEASE; COHORT ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE MARKER; DISEASE SEVERITY; FATTY LIVER; GENE EXPRESSION; GENOTYPE; HEPATITIS C; HUMAN; LETTER; LIVER CIRRHOSIS; LIVER FUNCTION; LIVER TRANSPLANTATION; NONALCOHOLIC FATTY LIVER; NONHUMAN; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; ADULT; BLOOD; FEMALE; LIVER FUNCTION TEST; MALE; METABOLISM; NOTE; VIROLOGY;

ADULT; BIOLOGICAL MARKERS; FATTY LIVER; FEMALE; HEPATITIS C, CHRONIC; HUMANS; LIVER FUNCTION TESTS; MALE; RETINOL-BINDING PROTEINS, PLASMA;

EID: 56149095010     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22544     Document Type: Letter

References (8)

1. Petta S, Cammà C, Di Marco V, Alessi N, Barbaria F, Cabibi D, et al. Retinol-binding protein 4: A new marker of virus-induced steatosis in patients infected with hepatitis C virus genotype 1. HEPATOLOGY 2008;48: 28-37.
2. Graham TE, Yang Q, Bluher M, Hammarstedt A, Ciaraldi TP, Henry RR, et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N Engl J Med 2006;354:2552-2563.
3. Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 2005;436:356-362.
4. Yagmur E, Weiskirchen R, Gressner AM, Trautwein C, Tacke F. Insulin resistance in liver cirrhosis is not associated with circulating retinol-binding protein 4. Diabetes Care 2007;30:1168-1172.
5. Bahr MJ, Boeker KH, Manns MP, Tietge UJ. Decreased hepatic RBP4 secretion is correlated with reduced hepatic glucose production but not associated with insulin resistance in patients with liver cirrhosis. Clin Endocrinol (Oxf) 2008; doi: 10.1111/j.1365-2265.2008.03295.x.
6. Tacke F, Wustefeld T, Horn R, Luedde T, Srinivas RA, Manns MP, et al. High adiponectin in chronic liver disease and cholestasis suggests biliary route of adiponectin excretion in vivo. J Hepatol 2005;42:666-673.
7. Yagmur E, Trautwein C, Gressner AM, Tacke F. Resistin serum levels are associated with insulin resistance, disease severity, clinical complications, and prognosis in patients with chronic liver diseases. Am J Gastroenterol 2006;101:1244-1252.
8. Seo JA, Kim NH, Park SY, Kim HY, Ryu OH, Lee KW, et al. Serum retinol-binding protein 4 levels are elevated in non-alcoholic fatty liver disease. Clin Endocrinol (Oxf) 2008;68:555-560.