-
1
-
-
27144483559
-
Microvascular dysfunction as a cause of organ dysfunction in severe sepsis
-
Vincent JL, De Backer D. Microvascular dysfunction as a cause of organ dysfunction in severe sepsis. Crit Care 2005;9(suppl 4): S9-S12
-
(2005)
Crit Care
, vol.9
, Issue.SUPPL. 4
-
-
Vincent, J.L.1
De Backer, D.2
-
2
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-77
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
Ressler, J.4
Muzzin, A.5
Knoblich, B.6
Peterson, E.7
Tomlanovich, M.8
-
3
-
-
0035826096
-
Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ Jr; Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;344:699-709
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
LaRosa, S.P.4
Dhainaut, J.F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Fisher Jr, C.J.11
-
4
-
-
27144476216
-
Microcirculatory alterations in ischemiareperfusion injury and sepsis: Effects of activated protein C and thrombin inhibition
-
Hoffmann JN, Vollmar B, Laschke MW, Fertmann JM, Jauch KW, Menger MD. Microcirculatory alterations in ischemiareperfusion injury and sepsis: effects of activated protein C and thrombin inhibition. Crit Care 2005;9(suppl 4):S33-S37
-
(2005)
Crit Care
, vol.9
, Issue.SUPPL. 4
-
-
Hoffmann, J.N.1
Vollmar, B.2
Laschke, M.W.3
Fertmann, J.M.4
Jauch, K.W.5
Menger, M.D.6
-
5
-
-
0036155210
-
Antithrombin effects on endotoxin-induced microcirculatory disorders are mediated mainly by its interaction with microvascular endothelium
-
Hoffmann JN, Vollmar B, Romisch J, Inthorn D, Schildberg FW, Menger MD. Antithrombin effects on endotoxin-induced microcirculatory disorders are mediated mainly by its interaction with microvascular endothelium. Crit Care Med 2002;30:218-25
-
(2002)
Crit Care Med
, vol.30
, pp. 218-225
-
-
Hoffmann, J.N.1
Vollmar, B.2
Romisch, J.3
Inthorn, D.4
Schildberg, F.W.5
Menger, M.D.6
-
6
-
-
0035904368
-
KyberSept Trial Study Group. Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: A randomized controlled trial
-
Warren BL, Eid A, Singer P, Pillay SS, Carl P, Novak I, Chalupa P, Atherstone A, Penzes I, Kubler A, Knaub S, Keinecke HO, Heinrichs H, Schindel F, Juers M, Bone RC, Opal SM; KyberSept Trial Study Group. Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial. JAMA 2001;286:1869-78
-
(2001)
JAMA
, vol.286
, pp. 1869-1878
-
-
Warren, B.L.1
Eid, A.2
Singer, P.3
Pillay, S.S.4
Carl, P.5
Novak, I.6
Chalupa, P.7
Atherstone, A.8
Penzes, I.9
Kubler, A.10
Knaub, S.11
Keinecke, H.O.12
Heinrichs, H.13
Schindel, F.14
Juers, M.15
Bone, R.C.16
Opal, S.M.17
-
7
-
-
21244438366
-
Tissue factor pathway inhibitor and antithrombin trial results
-
LaRosa SP, Opal SM. Tissue factor pathway inhibitor and antithrombin trial results. Crit Care Clin 2005;21:433-48
-
(2005)
Crit Care Clin
, vol.21
, pp. 433-448
-
-
LaRosa, S.P.1
Opal, S.M.2
-
8
-
-
0027132478
-
A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study
-
Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 1993;270:2957-63
-
(1993)
JAMA
, vol.270
, pp. 2957-2963
-
-
Le Gall, J.R.1
Lemeshow, S.2
Saulnier, F.3
-
9
-
-
0028961486
-
Customized probability models for early severe sepsis in adult intensive care patients. Intensive Care Unit Scoring Group
-
Le Gall JR, Lemeshow S, Leleu G, Klar J, Huillard J, Rue M, Teres D, Artigas A. Customized probability models for early severe sepsis in adult intensive care patients. Intensive Care Unit Scoring Group. JAMA 1995;273:644-50
-
(1995)
JAMA
, vol.273
, pp. 644-650
-
-
Le Gall, J.R.1
Lemeshow, S.2
Leleu, G.3
Klar, J.4
Huillard, J.5
Rue, M.6
Teres, D.7
Artigas, A.8
-
10
-
-
31344451275
-
High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: Efficacy and safety
-
for the KyberSept investigators
-
Wiedermann CJ, Hoffmann JN, Juers M, Ostermann H, Kienast J, Briegel J, Strauss R, Keinecke H-O, Warren BL, Opal SM, for the KyberSept investigators. High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: efficacy and safety. Crit Care Med 2006;34:285-92
-
(2006)
Crit Care Med
, vol.34
, pp. 285-292
-
-
Wiedermann, C.J.1
Hoffmann, J.N.2
Juers, M.3
Ostermann, H.4
Kienast, J.5
Briegel, J.6
Strauss, R.7
Keinecke, H.-O.8
Warren, B.L.9
Opal, S.M.10
-
11
-
-
33644859949
-
Treatment effects of highdose antithrombin III without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation
-
for the KyberSept investigators
-
Kienast J, Juers M, Wiedermann CJ, Hoffmann JN, Ostermann H, Strauss R, Keinecke H-O, Warren BL, Opal SM, for the KyberSept investigators. Treatment effects of highdose antithrombin III without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation. J Thromb Haemost 2006;4:90-7
-
(2006)
J Thromb Haemost
, vol.4
, pp. 90-97
-
-
Kienast, J.1
Juers, M.2
Wiedermann, C.J.3
Hoffmann, J.N.4
Ostermann, H.5
Strauss, R.6
Keinecke, H.-O.7
Warren, B.L.8
Opal, S.M.9
-
12
-
-
4444237509
-
Effect of long-term and high-dose antithrombin supplementation on coagulation and fibrinolysis in patients with severe sepsis
-
Hoffmann JN, Muhlbayer D, Jochum M, Inthorn D. Effect of long-term and high-dose antithrombin supplementation on coagulation and fibrinolysis in patients with severe sepsis. Crit Care Med 2004;32:1851-9
-
(2004)
Crit Care Med
, vol.32
, pp. 1851-1859
-
-
Hoffmann, J.N.1
Muhlbayer, D.2
Jochum, M.3
Inthorn, D.4
-
13
-
-
0031266015
-
Antithrombin III supplementation in severe sepsis: Beneficial effects on organ dysfunction
-
Inthorn D, Hoffmann JN, Hartl WH, Muhlbayer D, Jochum M. Antithrombin III supplementation in severe sepsis: beneficial effects on organ dysfunction. Shock 1997;8:328-34
-
(1997)
Shock
, vol.8
, pp. 328-334
-
-
Inthorn, D.1
Hoffmann, J.N.2
Hartl, W.H.3
Muhlbayer, D.4
Jochum, M.5
-
14
-
-
25444492831
-
Administration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis (ADDRESS) Study Group. Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death
-
Abraham E, Laterre PF, Garg R, Levy H, Talwar D, Trzaskoma BL, Francois B, Guy JS, Bruckmann M, Rea-Neto A, Rossaint R, Perrotin D, Sablotzki A, Arkins N, Utterback BG, Macias WL; Administration of Drotrecogin Alfa (Activated) in Early Stage Severe Sepsis (ADDRESS) Study Group. Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. N Engl J Med 2005;353:1332-41
-
(2005)
N Engl J Med
, vol.353
, pp. 1332-1341
-
-
Abraham, E.1
Laterre, P.F.2
Garg, R.3
Levy, H.4
Talwar, D.5
Trzaskoma, B.L.6
Francois, B.7
Guy, J.S.8
Bruckmann, M.9
Rea-Neto, A.10
Rossaint, R.11
Perrotin, D.12
Sablotzki, A.13
Arkins, N.14
Utterback, B.G.15
Macias, W.L.16
-
15
-
-
33646455014
-
KyberSept investigators. Benefit/risk profile of high-dose antithrombin in patients with severe sepsis treated with and without concomitant heparin
-
Hoffmann JN, Wiedermann CJ, Juers M, Ostermann H, Kienast J, Briegel J, Strauss R, Warren BL, Opal SM; KyberSept investigators. Benefit/risk profile of high-dose antithrombin in patients with severe sepsis treated with and without concomitant heparin. Thromb Haemost 2006;95:850-6
-
(2006)
Thromb Haemost
, vol.95
, pp. 850-856
-
-
Hoffmann, J.N.1
Wiedermann, C.J.2
Juers, M.3
Ostermann, H.4
Kienast, J.5
Briegel, J.6
Strauss, R.7
Warren, B.L.8
Opal, S.M.9
-
16
-
-
33745610509
-
Baseline severity of sepsis in subjects of the prowess and the Kybersept clinical trials on endogenous anticoagulants
-
Wiedermann CJ, Keinecke HO, Jü rs M, Opal SM. Baseline severity of sepsis in subjects of the prowess and the Kybersept clinical trials on endogenous anticoagulants. Shock 2006; 25:657-8
-
(2006)
Shock
, vol.25
, pp. 657-658
-
-
Wiedermann, C.J.1
Keinecke, H.O.2
Jü rs, M.3
Opal, S.M.4
|