The Adjuvant Benefit of Angioplasty in Patients with Mild to Moderate Intermittent Claudication (MIMIC) Managed by Supervised Exercise, Smoking Cessation Advice and Best Medical Therapy: Results from Two Randomised Trials for Stenotic Femoropopliteal and Aortoiliac Arterial Disease

European Journal of Vascular and Endovascular Surgery

Volumn 36, Issue 6, 2008, Pages 680-688

[No Author Info available]

Author keywords

ABPI; Aortoiliac; Femoropopliteal; Intermittent claudication; Occlusive or stenotic arterial disease; Percutaenous transluminal angioplasty; Treadmill test; Walking distance

Indexed keywords

AGED; ANKLE BRACHIAL INDEX; AORTOILIAC ARTERIAL DISEASE; ARTERY DISEASE; ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXERCISE; FEMALE; HUMAN; INTERMITTENT CLAUDICATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SMOKING CESSATION; TREADMILL; TREATMENT DURATION; WALKING;

AGED; ANGIOPLASTY, BALLOON; AORTA, ABDOMINAL; ARTERIAL OCCLUSIVE DISEASES; EXERCISE THERAPY; FEMALE; FEMORAL ARTERY; FOLLOW-UP STUDIES; HUMANS; ILIAC ARTERY; INTERMITTENT CLAUDICATION; MALE; MIDDLE AGED; POPLITEAL ARTERY; SEVERITY OF ILLNESS INDEX; SMOKING CESSATION;

EID: 56149088903     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2008.10.007     Document Type: Article

References (24)

1. Creasy T.S., McMillan P.J., Fletcher E.W., Collin J., and Morris P.J. Is percutaneous transluminal angioplasty better than exercise for claudication? Preliminary results from a prospective randomised trial. Eur J Vasc Surg 4 2 (1990) 135-140
2. Perkins J.M., Collin J., Creasy T.S., Fletcher E.W., and Morris P.J. Exercise training versus angioplasty for stable claudication. Long and medium term results of a prospective, randomised trial. Eur J Vasc Endovasc Surg 11 4 (1996) 409-413
3. Whyman M.R., Fowkes F.G., Kerracher E.M., Gillespie I.N., Lee A.J., Housley E., et al. Randomised controlled trial of percutaneous transluminal angioplasty for intermittent claudication. Eur J Vasc Endovasc Surg 12 2 (1996) 167-172
4. Whyman M.R., Fowkes F.G., Kerracher E.M., Gillespie I.N., Lee A.J., Housley E., et al. Is intermittent claudication improved by percutaneous transluminal angioplasty? A randomized controlled trial. J Vasc Surg 26 4 (1997) 551-557
5. Fowkes F.G., and Gillespie I.N. Angioplasty (versus non surgical management) for intermittent claudication. Cochrane Database Syst Rev 2 (2000) CD000017
6. Gardner A.W., and Poehlman E.T. Exercise rehabilitation programs for the treatment of claudication pain. A meta-analysis. JAMA 274 12 (1995) 975-980
7. Leng G.C., Fowler B., and Ernst E. Exercise for intermittent claudication. Cochrane Database Syst Rev 2 (2000) CD000990
8. Watson L., Ellis B., and Leng G.C. Exercise for intermittent claudication. Cochrane Database Syst Rev 4 (2008) CD000990
9. Bendermacher B.L., Willigendael E.M., Teijink J.A., and Prins M.H. Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication. Cochrane Database Syst Rev 2 (2006) CD005263
10. Kruidenier L.M., Bendermacher B.L., Willigendael E.M., Teijink J.A., and Prins M.H. From the Cochrane Library: increased walking distance through supervised exercise therapy in patients with intermittent claudication. Ned Tijdschr Geneeskd 152 6 (2008) 321-323
11. Tetteroo E., Van der G.Y., Bosch J.L., van Engelen A.D., Hunink M.G., Eikelboom B.C., et al. Randomised comparison of primary stent placement versus primary angioplasty followed by selective stent placement in patients with iliac-artery occlusive disease Dutch Iliac Stent Trial Study Group. Lancet 351 9110 (1998) 1153-1159
12. Krankenberg H., Schluter M., Steinkamp H.J., Burgelin K., Scheinert D., Schulte K.L., et al. Nitinol stent implantation versus percutaneous transluminal angioplasty in superficial femoral artery lesions up to 10 cm in length: the femoral artery stenting trial (FAST). Circulation 116 3 (2007) 285-292
13. Zeller T., Tiefenbacher C., Steinkamp H.J., Langhoff R., Wittenberg G., Schluter M., et al. Nitinol stent implantation in TASC A and B superficial femoral artery lesions: the Femoral Artery Conformexx Trial (FACT). J Endovasc Ther 15 4 (2008) 390-398
14. Edwards' Resilient Trial Demonstrates Statistically Superior Results for Treating Peripheral Arterial Disease in the Leg. Available from: (2008). [accessed 25.09.08]
15. Leng G.C., and Fowkes F.G. The Edinburgh claudication questionnaire: an improved version of the WHO/Rose questionnaire for use in epidemiological surveys. J Clin Epidemiol 45 10 (1992) 1101-1109
16. Laing S.P., and Greenhalgh R.M. Standard exercise test to assess peripheral arterial disease. Br Med J 280 6206 (1980) 13-16
17. Cheetham D.R., Burgess L., Ellis M., Williams A., Greenhalgh R.M., and Davies A.H. Does supervised exercise offer adjuvant benefit over exercise advice alone for the treatment of intermittent claudication? A randomised trial. Eur J Vasc Endovasc Surg 27 1 (2004) 17-23
18. Ware Jr. J.E., and Sherbourne C.D. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30 6 (1992) 473-483
19. Spronk S., Bosch J.L., den Hoed P.T., Veen H.F., Pattynama P.M., and Hunink M.M. Cost-effectiveness of endovascular revascularization compared to supervised hospital-based exercise training in patients with intermittent claudication: a randomized controlled trial. J Vasc Surg 48 6 (2008) 1469-1477
20. Mondillo S., Ballo P., Barbati R., Guerrini F., Ammaturo T., Agricola E., et al. Effects of simvastatin on walking performance and symptoms of intermittent claudication in hypercholesterolemic patients with peripheral vascular disease. Am J Med 114 5 (2003) 359-364
21. Mohler III E.R., Hiatt W.R., and Creager M.A. Cholesterol reduction with atorvastatin improves walking distance in patients with peripheral arterial disease. Circulation 108 12 (2003) 1481-1486
22. Murphy T.P., Hirsch A.T., Ricotta J.J., Cutlip D.E., Mohler E., Regensteiner J.G., et al. The claudication: exercise vs. endoluminal revascularization (CLEVER) study: rationale and methods. J Vasc Surg 47 6 (2008) 1356-1363
23. Schillinger M., Sabeti S., Loewe C., Dick P., Amighi J., Mlekusch W., et al. Balloon angioplasty versus implantation of nitinol stents in the superficial femoral artery. N Engl J Med 354 18 (2006) 1879-1888
24. Schillinger M., Sabeti S., Dick P., Amighi J., Mlekusch W., Schlager O., et al. Sustained benefit at 2 years of primary femoropopliteal stenting compared with balloon angioplasty with optional stenting. Circulation 115 21 (2007) 2745-2749