Effects of D-cycloserine administration on weekly nonemotional memory tasks in healthy participants

Psychotherapy and Psychosomatics

Volumn 78, Issue 1, 2008, Pages 49-54

  Otto, Michael W ^a   Basden, Shawnee L ^a   McHugh, R Kathryn ^a   Kantak, Kathleen M ^a   Deckersbach, Thilo ^b   Cather, Corinne ^b   Goff, Donald C ^b   Hofmann, Stefan G ^a   Berry, Angela C ^c   Smits, Jasper A J ^c  

^a BOSTON UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c SOUTHERN METHODIST UNIVERSITY   (United States)

Author keywords

D Cycloserine; Learning tasks; Memory tasks

Indexed keywords

CYCLOSERINE; PLACEBO;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG MECHANISM; EFFECT SIZE; FEMALE; HUMAN; HUMAN EXPERIMENT; LEARNING; MALE; NEUROPSYCHOLOGICAL TEST; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TASK PERFORMANCE; VERBAL MEMORY; WORD LIST RECALL;

AFFECT; ANTIMETABOLITES; CYCLOSERINE; DRUG ADMINISTRATION SCHEDULE; HEALTH STATUS; HUMANS; LEARNING; MEMORY; MENTAL RECALL; NEUROPSYCHOLOGICAL TESTS; TRAIL MAKING TEST;

EID: 56149085858     PISSN: 00333190     EISSN: None     Source Type: Journal    
DOI: 10.1159/000172620     Document Type: Article

References (35)

1. Ressler KJ, Rothbaum BO, Tannenbaum L, Anderson P, Graap K, Zimand E, Hodges L, Davis M: Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear. Arch Gen Psychiatry 2004;61:1136-1144.
2. Hofmann SG, Meuret AE, Smits JAJ, Simon NM, Pollack MH, Eisenmenger K, Shiekh M, Otto MW: Augmentation of exposure therapy with D-cycloserine for social anxiety disorder. Arch Gen Psychiatry 2006;63:298-304.
3. Guastella AJ, Richardson R, Lovibond PF, Rapee RM, Gaston JE, Mitchell P, Dadds MR: A randomized controlled trial of D-cycloserine enhancement of exposure therapy for social anxiety disorder. Biol Psychiatry 2008;63:544-549.
4. Kushner MG, Kim SW, Donahue C, Thuras P, Adson D, Kotlyar M, McCabe J, Peterson J, Foa EB: D-Cycloserine augmented exposure therapy for obsessive compulsive disorder. Biol Psychiatry 2007;62:835-838.
5. Storch EA, Merlo LJ, Bengtson M, Murphy TK, Lewis MH, Yang MC, Jacob ML, Larson M, Hirsh A, Fernandez M, Geffken GR, Goodman WK: D-Cycloserine does not enhance exposure-response prevention therapy in obsessive-compulsive disorder. Int Clin Psychopharmacol 2007;22:230-237.
6. Wilhelm S, Buhlmann U, Tolin DF, Meunier SA, Pearlson GD, Reese HE, Cannistraro P, Jenike MA, Rauch SL: Augmentation of behavior therapy with D-cycloserine for obsessive-compulsive disorder. Am J Psychiatry 2008;165:335-341.
7. Norberg MM, Krystal JH, Tolin DF: A meta-analysis of D- cycloserine and the facilitation of fear extinction and exposure therapy. Biol Psychiatry, in press.
8. Davis M, Ressler K, Rothbaum BO, Richardson R: Effects of D-cycloserine on extinction: translation from preclinical to clinical work. Biol Psychiatry 2006;60:369-375.
9. Ledgerwood L, Richardson R, Cranney J: D-Cycloserine facilitates extinction of learned fear: effects of reacquisition and generalized extinction. Biol Psychiatry 2005;57:841-847.
10. Richardson R, Ledgerwood L, Cranney J: Facilitation of fear extinction by D-cycloserine: theoretical and clinical implications. Learn Mem 2004;11:510-516.
11. Ledgerwood L, Richardson R, Cranney J: Effects of D-cycloserine on extinction of conditioned freezing. Behav Neurosci 2003;117:341-349.
12. Barlow DH: Clinical Handbook of Psychological Disorders, ed 4. New York, Guilford Press, 2001.
13. Hofmann, SG, Tompson, MC: Treating Chronic and Severe Mental Disorders: A Handbook of Empirically Supported Interventions. New York, Guilford Press, 2002.
14. Thompson LT, Disterhoft JF: Age- and dose-dependent facilitation of associative eyeblink conditioning by D-cycloserine in rabbits. Behav Neurosci 1997;111:1303-1312.
15. Land C, Riccio D: D-Cycloserine: effects on long-term retention of a conditioned response and on memory for contextual attributes. Neurobiol Learn Mem 1999;72:158-168.
16. Lelong V, Dauphin F, Boulouard M: RS 67333 and D-cycloserine accelerate learning acquisition in the rat. Neuropharmacology 2001;41:517-522.
17. Pussinen R, Nieminen S, Koivisto E, Haapalinna A, Riekkinen P, Sirvio J: Enhancement of intermediate-term memory by an alpha-1 agonist or a partial agonist at the glycine site of the NMDA receptor. Neurobiol Learn Mem 1997;67:69-74.
18. Pussinen R, Sirvio J: Effects of D-cycloserine, a positive modulator of N-methyl- D-aspartate receptors, and ST 587, a putative alpha-1 adrenergic agonist, individually and in combination, on the non-delayed and delayed foraging behaviour of rats assessed in the radial arm maze. J Psychopharmacol 1999;13:171-179.
19. Johannesen TS, Myhrer T: Impaired visual memory in rats reared in isolation is revered by D-cycloserine in the adult rat. Eur J Pharmacol 2002;437:73-77.
20. Hughes RN: Responsiveness to brightness change in male and female rats following treatment with the partial agonist of the N-methyl-D- aspartate receptor, D-cycloserine. Behav Brain Res 2004;152:199-207.
21. Squire LR, Stark CE, Clark RE: The medial temporal lobe. Annu Rev Neurosci 2004;27:279-306.
22. Mao SC, Hsiao YH, Gean PW: Extinction training in conjunction with a partial agonist of the glycine site on the NMDA receptor erases memory trace. J Neurosci 2006;26:8892-8899.
23. Matsuoka N, Aigner TG: D-Cycloserine, a partial agonist at the glycine site couples to N-methyl- D-aspartate receptors, improves visual recognition memory in rhesus monkeys. J Pharmacol Exp Ther 1996;278:891-897.
24. Lezak MD: Neuropsychological Assessment, ed 3. New York, Oxford University Press, 1995.
25. Halstead WC: Brain and Intelligence. Chicago, University of Chicago Press, 1947.
26. Reitan RM: Investigation of the validity of Halstead's measure of biological intelligence. AMA Arch Neurol Psychiatry 1955;73:28-35.
27. Benton AL, Hamsher KD, Sivan AB: Multilingual Aphasia Examination. Iowa City, AJA Associates, 1994.
28. Spreen O, Strauss E: A Compendium of Neuropsychological Tests: Administration, Norms, and Commentary, ed 2. New York, Oxford University Press, 1998.
29. Delis DC, Kramer JL, Kaplan E, Ober BA: California Verbal Memory Test: Manual. San Antonio, Psychological Corporation, 1987.
30. Wechsler D: Wechsler Memory Scale - Revised. New York, Psychological Corp, 1987.
31. Graf P, Schacter DL: Implicit and explicit memory for new associations in normal and amnesic subjects. J Exp Psychol Learn Mem Cogn 1985;11:501-518.
32. Schacter DL: Implicit expressions of memory in organic amnesia: learning of new facts and associations. Hum Neurobiol 1987;6:107-118.
33. Hubley AM, Tremblay D: Comparability of total score performance on the Rey-Osterrieth Complex Figure and a modified Taylor Complex Figure. J Clin Exp Neuropsychol 2002;24:370-382.
34. Meyers J, Meyers K: Rey Complex Figure Test and Recognition Trial: Professional Manual. Florida, Psychological Assessment Resources, 1995.
35. Bailey JE, Papdopoulos A, Lingford-Hughes A, Nutt DJ: D-Cycloserine and performance under different states of anxiety in healthy volunteers. Psychopharmacology 2007;193:579-585.