Successful treatment of primary cutaneous Aspergillus ustus infection with surgical debridement and a combination of voriconazole and terbinafine

Diagnostic Microbiology and Infectious Disease

Volumn 62, Issue 4, 2008, Pages 443-446

  Krishnan Natesan, Suganthini ^a,b   Chandrasekar, Pranatharthi H ^a   Manavathu, Elias K ^a   Revankar, Sanjay G ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Aspergillus ustus; Combination therapy; Cutaneous infection; Immunocompromised; Terbinafine; Voriconazole resistance

Indexed keywords

AMPHOTERICIN B; CASPOFUNGIN; ITRACONAZOLE; TERBINAFINE; VORICONAZOLE;

ARTICLE; ASPERGILLOSIS; ASPERGILLUS USTUS; CONTROLLED STUDY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FUNGUS CULTURE; FUNGUS ISOLATION; HUMAN; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL;

ANTIFUNGAL AGENTS; ASPERGILLOSIS; ASPERGILLUS; DEBRIDEMENT; DRUG RESISTANCE, FUNGAL; DRUG THERAPY, COMBINATION; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; NAPHTHALENES; PYRIMIDINES; SOFT TISSUE INFECTIONS; TRIAZOLES;

EID: 56049125932     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2008.08.003     Document Type: Article

References (13)

1. Garcia-Effron G., Gomez-Lopez A., Mellado A., et al. In vitro activity of terbinafine against medically important non-dermatophyte species of filamentous fungi. J. Antimicrob. Chemother 53 (2004) 1086-1089
2. Iwen P.C., Rupp M.E., Bishop M.R., et al. Disseminated aspergillosis caused by Aspergillus ustus in a patient following allogeneic peripheral stem cell transplantation. J. Clin. Microbiol. 36 (1998) 3713-3717
3. Josepa Gene J., Azón-Masoliver A., Guarro J., et al. Cutaneous infections caused by Aspergillus ustus, an emerging opportunistic fungus in immunosuppressed patients. J. Clin. Microbiol 39 (2001) 1134-1136
4. Kantarcioǧlu A.S., and Yucel A. In-vitro activities of terbinafine, itraconazole and amphotericin B against Aspergillus and Cladosporium species. J. Chemother 14 (2002) 562-567
5. Karaarslan A., Arikan S., Ozcan M., et al. In vitro activity of terbinafine and itraconazole against Aspergillus species isolated from otomycosis. Mycoses 47 (2004) 284-287
6. Mosquera J., Sharp A., Moore C.B., et al. In vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine against Aspergillus spp. J. Antimicrob. Chemother 50 (2002) 189-194
7. Panackal A.A., Imhof A., Hanley E.W., et al. Aspergillus ustus infections among transplant recipients. Emerg. Infect. Dis 12 (2006) 403-408
8. Pavie J., Lacroix C., Hermoso D.G., et al. Breakthrough disseminated Aspergillus ustus infection in allogeneic hematopoietic stem cell transplant recipients receiving voriconazole or caspofungin prophylaxis. J. Clin. Microbiol. 43 (2005) 4902-4904
9. Ryder N.S., and Leitner I. Synergisitc interaction of terbinafine with triazoles or amphotericin B against Aspergillus species. Med. Mycol 39 (2001) 91-95
10. Saracli M.A., Mutlu F.M., Yildiran S.T., et al. Clustering of invasive Aspergillus ustus eye infections in a tertiary care hospital: a molecular epidemiologic study of an uncommon species. Med. Mycol. 45 (2007) 377-384
11. Verweij P.E., van den Bergh M.F.Q., Rath P.M., et al. Invasive aspergillosis caused by Aspergillus ustus: case report and review. J. Clin. Microbiol 37 (1999) 1606-1609
12. Varga J., et al. Aspergillus calidoustus sp. nov., causative agent of human infections previously assigned to Aspergillus ustus. Eukaryot. Cell 7 (2008) 630-638
13. Yildiran S.T., Mutlu F.M., Saracli M.A., et al. Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery. Med. Mycol 44 (2006) 665-669