Prognostic factors for hospital mortality and ICU admission in patients with ANCA-related pulmonary vasculitis

American Journal of the Medical Sciences

Volumn 336, Issue 4, 2008, Pages 321-326

  Holguin, Fernando ^a,b   Ramadan, Bassel ^a   Gal, Anthony A ^a,b   Roman, Jesse ^a,b,c  

^a Division of Pulmonary   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

ANCA; Hospitalization; Mortality; Predictive factors; Prognosis; Pulmonary vasculitis

Indexed keywords

CORTICOSTEROID; CYCLOPHOSPHAMIDE; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; NEUTROPHIL CYTOPLASMIC ANTIBODY;

ACUTE KIDNEY FAILURE; ADULT; AGED; ANCA ASSOCIATED VASCULITIS; ANEMIA; ANTIBODY TITER; ARTHRALGIA; ARTICLE; ARTIFICIAL VENTILATION; BLOOD TRANSFUSION; BONE MARROW SUPPRESSION; CAPILLARITIS; CLINICAL FEATURE; COUGHING; DYSPNEA; FEMALE; FEVER; GRANULOMATOUS INFLAMMATION; HEMODIALYSIS; HEMOPTYSIS; HUMAN; HYPERTENSION; INFECTION; INTENSIVE CARE UNIT; KIDNEY FAILURE; LUNG HEMORRHAGE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MORTALITY; OPEN LUNG BIOPSY; PLASMAPHERESIS; PREDICTION; PREDICTOR VARIABLE; PROGNOSIS; PULMONARY VASCULITIS; RENAL REPLACEMENT THERAPY; RESPIRATORY FAILURE; SCLERITIS; SINUSITIS; SMOKING; THORACOSCOPY;

EID: 56049114700     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAJ.0b013e31816805fa     Document Type: Article

References (32)

1. Davies DJ, Moran JE, Niall JF, et al. Segmental necrotising glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology? Br Med J (Clin Res Ed) 1982;285:606.
2. Lenclud C, De VP, Dupont E, et al. Wegener's granulomatosis presenting as acute respiratory failure with anti-neutrophil-cytoplasm antibodies. Chest 1989;96:345-7.
3. Davson J, Ball J, Platt R. The kidney in periarteritis nodosa. Q J Med 1948;17:175-202.
4. Jennette JC, Falk RJ. Small-vessel vasculitis. N Engl J Med 1997;337:1512-23.
5. Schwarz MI, Brown KK. Small vessel vasculitis of the lung. Thorax 2000;55:502-10.
6. Falk RJ, Jennette JC. Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med 1988;318:1651-7.
7. Guillevin L, Durand-Gasselin B, Cevallos R, et al. Microscopic polyangiitis: clinical and laboratory findings in eighty-five patients. Arthritis Rheum 1999;42:421-30.
8. Adu D, Howie A, Scott D. Polyarteritis and the kidney. Q J Med 1987;62:221-37.
9. Bosch X, Lopez-Soto A, Mirapeix E, et al. Antineutrophil cytoplasmic autoantibody-associated alveolar capillaritis in patients presenting with pulmonary hemorrhage. Arch Pathol Lab Med 1994;118:517-22.
10. Cotch MF, Hoffman GS, Yerg DE, et al. The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources. Arthritis Rheum 1996;39:87-92.
11. Lens XM, Montoliu J, Pascual B, et al. [Diffuse pulmonary hemorrhage in Wegener's granulomatosis. Presentation of a case and review of the literature]. Rev Clin Esp 1985;177:333-6.
12. Travis WD, Colby TV, Lombard C, et al. A clinicopathologic study of 34 cases of diffuse pulmonary hemorrhage with lung biopsy confirmation. Am J Surg Pathol 1990;14:1112-25.
13. Green HJ, Ruoss SJ, Kraft SA, et al. Pulmonary capillaritis and alveolar hemorrhage. Update on diagnosis and management. Chest 1996;110:1305-16.
14. Travis WD, Hoffman GS, Leavitt RY, et al. Surgical pathology of the lung in Wegener's granulomatosis. Review of 87 open lung biopsies from 67 patients. Am J Surg Pathol 1991;15:315-33.
15. Falk RJ, Terrell RS, Charles LA, et al. Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc Natl Acad Sci USA 1990;87:4115-9.
16. Jennette JC. Pathogenic potential of anti-neutrophil cytoplasmic autoantibodies. Lab Invest 1994;70:135-7.
17. Cohen BA, Clark WF. Pauci-immune renal vasculitis: natural history, prognostic factors, and impact of therapy. Am J Kidney Dis 2000;36:914-24.
18. Burns A. Pulmonary vasculitis. Thorax 1998;53:220-7.
19. Hogan SL, Nachman PH, Wilkman AS, et al. Prognostic markers in patients with antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis. J Am Soc Nephrol 1996;7:23-32.
20. Burkhardt O, Kohnlein T, Wrenger E, et al. Predicting outcome and survival in patients with Wegener's granulomatosis treated on the intensive care unit. Scand J Rheumatol 2007;36:119-24.
21. Ewert BH, Jennette JC, Falk RJ. Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells. Kidney Int 1992;41:375-83.
22. Savage CO, Pottinger BE, Gaskin G, et al. Autoantibodies developing to myeloperoxidase and proteinase 3 in systemic vasculitis stimulate neutrophil cytotoxicity toward cultured endothelial cells. Am J Pathol 1992;141:335-42.
23. Cordier JF. A lung biopsy is unnecessary in the management of ANCA-positive patients with chest-roentgenographic abnormalities. Sarcoidosis Vasc Diffuse Lung Dis 1996;13:235-7.
24. Schwarz MI, Sutarik JM, Nick JA, et al. Pulmonary capillaritis and diffuse alveolar hemorrhage. A primary manifestation of polymyositis. Am J Respir Crit Care Med 1995; 151:2037-40.
25. Bindi P, Mougenot B, Mentre F, et al. Necrotizing crescentic glomerulonephritis without significant immune deposits: a clinical and serological study. Q J Med 1993;86:55-68.
26. Savage CO. Microscopic polyarteritis: definition and relation to Wegener's granulomatosis. APMIS Suppl. 1989;6:8-9.
27. Serra A, Cameron JS, Turner DR, et al. Vasculitis affecting the kidney: presentation, histopathology and long-term outcome. Q J Med 1984;53:181-207.
28. Khan SA, Subla MR, Behl D, et al. Outcome of patients with small-vessel vasculitis admitted to a medical ICU. Chest 2007;131:972-6.
29. Lauque D, Cadranel J, Lazor R, et al. Microscopic polyangiitis with alveolar hemorrhage. A study of 29 cases and review of the literature. Groupe d'Etudes et de Recherche sur les Maladies "Orphelines" Pulmonaires (GERM"O"P). Medicine (Baltimore) 2000;79:222-33.
30. Kamesh L, Harper L, Savage CO. ANCA-positive vasculitis. J Am Soc Nephrol 2002;13:1953-60.
31. Jayne D. Update on the European Vasculitis Study Group trials. Curr Opin Rheumatol 2001;13:48-55.
32. Lhote F, Cohen P, Genereau T, et al. Microscopic polyangiitis: clinical aspects and treatment. Ann Med Interne (Paris) 1996;147:165-77.