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Volumn 31, Issue 4, 2008, Pages 286-292

Novel 5‐Aminosalicylic Acid Formulations in Ulcerative Colitis:Old Dog, New Tricks

Author keywords

[No Author keywords available]

Indexed keywords

AMINOSALICYLIC ACID DERIVATIVE;

EID: 56049101168     PISSN: 1042895X     EISSN: 15389766     Source Type: Journal    
DOI: 10.1097/01.SGA.0000334035.94370.f6     Document Type: Article
Times cited : (2)

References (45)
  • 1
    • 85026141288 scopus 로고    scopus 로고
    • Retrieved May 16, 2008, from
    • Asacol prescribing information. (2007).
  • 2
    • 0036080280 scopus 로고    scopus 로고
    • Long-term maintenance treatment in ulcerative colitis: A 10-year follow-up.
    • Bresci, G., Parisi, G., Bertoni, M., & Capria, A. (2002). Long-term maintenance treatment in ulcerative colitis: A 10-year follow-up. Digestive & Liver Disease, 34(6), 419-423.
    • (2002) Digestive Liver Disease , vol.34 , Issue.6 , pp. 419-423
    • Bresci, G.1    Parisi, G.2    Bertoni, M.3    Capria, A.4
  • 3
    • 0038528399 scopus 로고    scopus 로고
    • Brunner, M., Greinwald, R., Kletter, K., Kvaternik, H., Corrado, M., Eichler, H., et al. (2003). Gastrointestinal transit and release of 5-aminosalicylic acid from 153Sm-labelled mesalazine pellets vs. tablets in male healthy volunteers. Alimentary Pharmacology & Therapeutics, 17(9), 1163-1169.
    • Brunner, M., Greinwald, R., Kletter, K., Kvaternik, H., Corrado, M., Eichler, H., et al. (2003). Gastrointestinal transit and release of 5-aminosalicylic acid from 153Sm-labelled mesalazine pellets vs. tablets in male healthy volunteers. Alimentary Pharmacology & Therapeutics, 17(9), 1163-1169.
  • 4
    • 4344602852 scopus 로고    scopus 로고
    • Guidelines for the management of inflammatory bowel disease in adults.
    • Carter, M. J., Lobo, A. J., & Travis, S. P. (2004). Guidelines for the management of inflammatory bowel disease in adults. Gut, 53(Suppl. V), v1-v16
    • (2004) Gut , vol.53 , pp. v1-v16
    • Carter, M.J.1    Lobo, A.J.2    Travis, S.P.3
  • 5
    • 21044448192 scopus 로고    scopus 로고
    • Casellas, F., Arenas, J. I., Baudet, J. S., Fabregas, S., Garcia, N., Gelabert, J., et al. (2005). Impairment of health-related quality of life in patients with inflammatory bowel disease: A Spanish multicenter study. Inflammatory Bowel Disease, 11(5), 488-496.
    • Casellas, F., Arenas, J. I., Baudet, J. S., Fabregas, S., Garcia, N., Gelabert, J., et al. (2005). Impairment of health-related quality of life in patients with inflammatory bowel disease: A Spanish multicenter study. Inflammatory Bowel Disease, 11(5), 488-496.
  • 7
    • 0034061366 scopus 로고    scopus 로고
    • A meta-analysis and overview of the literature on treatment options for left-sided ulcerative colitis and ulcerative proctitis.
    • Cohen, R. D., Woseth, D. M., Thisted, R. A., & Hanauer, S. B. (2000). A meta-analysis and overview of the literature on treatment options for left-sided ulcerative colitis and ulcerative proctitis. American Journal of Gastroenterology, 95, 1263-1276.
    • (2000) American Journal of Gastroenterology , vol.95 , pp. 1263-1276
    • Cohen, R.D.1    Woseth, D.M.2    Thisted, R.A.3    Hanauer, S.B.4
  • 8
    • 0030737685 scopus 로고    scopus 로고
    • d'Albasio, G., Pacini, F., Camarri, E., Messori, A., Trallori, G., Bonanomi, A. G., et al. (1997). Combined therapy with 5-aminosalicylic acid tablets and enemas for maintaining remission in ulcerative colitis: a randomized double-blind study. American Journal of Gastroenterology, 92(7), 1143-1147.
    • d'Albasio, G., Pacini, F., Camarri, E., Messori, A., Trallori, G., Bonanomi, A. G., et al. (1997). Combined therapy with 5-aminosalicylic acid tablets and enemas for maintaining remission in ulcerative colitis: a randomized double-blind study. American Journal of Gastroenterology, 92(7), 1143-1147.
  • 9
    • 0026784770 scopus 로고
    • Concentrations of 5-ASA and Ac-5-ASA in human ileocolonic biopsy homogenates after oral 5-ASA preparations.
    • De Vos, M., Verdievel, H., Schoonjans, R., Praet, M., Bogaert, M., & Barbier, F. (1992). Concentrations of 5-ASA and Ac-5-ASA in human ileocolonic biopsy homogenates after oral 5-ASA preparations. Gut, 33(10), 1338-1342.
    • (1992) Gut , vol.33 , Issue.10 , pp. 1338-1342
    • De Vos, M.1    Verdievel, H.2    Schoonjans, R.3    Praet, M.4    Bogaert, M.5    Barbier, F.6
  • 10
    • 85026150099 scopus 로고    scopus 로고
    • Dignass, A., Stijnen, T., Mross, M. R., Vermeire, S., Veerman, H., & Bhatt, A. (2007). Pentasa (mesalazine) once or twice daily for the management of maintenance of remission of ulcerative colitis: Demographic and baseline rata of a 12 month single blind randomised controlled trial. Gastroenterology, 132, A-502 (Abstract T1265).
    • Dignass, A., Stijnen, T., Mross, M. R., Vermeire, S., Veerman, H., & Bhatt, A. (2007). Pentasa (mesalazine) once or twice daily for the management of maintenance of remission of ulcerative colitis: Demographic and baseline rata of a 12 month single blind randomised controlled trial. Gastroenterology, 132, A-502 (Abstract T1265).
  • 11
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis.
    • Eaden, J. A., Abrams, K. R., & Mayberry, J. F. (2001). The risk of colorectal cancer in ulcerative colitis: A meta-analysis. Gut, 48(4), 526-535.
    • (2001) Gut , vol.48 , Issue.4 , pp. 526-535
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 12
    • 0034893382 scopus 로고    scopus 로고
    • Farup, P., Hinterleitner, T., Lukas, M., Hebuterne, X., Rachmilewitz, D., Campieri, M., et al. (2001). Mesalazine 4 g daily given as prolonged-release granules twice daily and four times daily is at least as effective as prolonged-release tablets four times daily in patients with ulcerative colitis. Inflammatory Bowel Disease, 7(3), 237-242.
    • Farup, P., Hinterleitner, T., Lukas, M., Hebuterne, X., Rachmilewitz, D., Campieri, M., et al. (2001). Mesalazine 4 g daily given as prolonged-release granules twice daily and four times daily is at least as effective as prolonged-release tablets four times daily in patients with ulcerative colitis. Inflammatory Bowel Disease, 7(3), 237-242.
  • 13
    • 0033850139 scopus 로고    scopus 로고
    • Frieri, G., Giacomelli, R., Pimpo, M., Palumbo, G., Passacantando, A., Pantaleoni, G., et al. (2000). Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with ulcerative colitis. Gut, 47(3), 410-414.
    • Frieri, G., Giacomelli, R., Pimpo, M., Palumbo, G., Passacantando, A., Pantaleoni, G., et al. (2000). Mucosal 5-aminosalicylic acid concentration inversely correlates with severity of colonic inflammation in patients with ulcerative colitis. Gut, 47(3), 410-414.
  • 14
    • 0032701176 scopus 로고    scopus 로고
    • Frieri, G., Pimpo, M. T., Palumbo, G. C., Onori, L., Viscido, A., Latella, G., et al. (1999). Rectal and colonic mesalazine concentration in ulcerative colitis: Oral vs. oral plus topical treatment. Alimentary Pharmacology & Therapeutics, 13(11), 1413-1417.
    • Frieri, G., Pimpo, M. T., Palumbo, G. C., Onori, L., Viscido, A., Latella, G., et al. (1999). Rectal and colonic mesalazine concentration in ulcerative colitis: Oral vs. oral plus topical treatment. Alimentary Pharmacology & Therapeutics, 13(11), 1413-1417.
  • 16
    • 0033031196 scopus 로고    scopus 로고
    • Gionchetti, P., Ardizzone, S., Benvenuti, M. E., Bianchi Porro, G., Biasco, G., Cesari, P., et al. (1999). A new mesalazine gel enema in the treatment of left-sided ulcerative colitis: A randomized controlled multicentre trial. Alimentary Pharmacology & Therapeutics, 13(3), 381-388.
    • Gionchetti, P., Ardizzone, S., Benvenuti, M. E., Bianchi Porro, G., Biasco, G., Cesari, P., et al. (1999). A new mesalazine gel enema in the treatment of left-sided ulcerative colitis: A randomized controlled multicentre trial. Alimentary Pharmacology & Therapeutics, 13(3), 381-388.
  • 17
    • 13944271403 scopus 로고    scopus 로고
    • Predictors of quality of life in ulcerative colitis: The importance of symptoms and illness representations.
    • Han, S. W., McColl, E., Barton, J. R., James, P., Steen, I. N., & Welfare, M. R. (2005). Predictors of quality of life in ulcerative colitis: The importance of symptoms and illness representations. Inflammatory Bowel Disease, 11(1), 24-34.
    • (2005) Inflammatory Bowel Disease , vol.11 , Issue.1 , pp. 24-34
    • Han, S.W.1    McColl, E.2    Barton, J.R.3    James, P.4    Steen, I.N.5    Welfare, M.R.6
  • 18
    • 85026150000 scopus 로고    scopus 로고
    • Hanauer, S., Sandborn, W., Kornbluth, A., Hardi, R., Regalli, G., & Yeh, C. (2005). Delayed-release oral mesalamine 4.8 g/day (800 mg tablet) versus 2.4 g/day (400 mg tablet) for treatment of moderately active ulcerative colitis: combined analysis of two randomised, double-blind, controlled trials. Gastroenterology, 128(4) (Suppl. 2), A-74-75 (Abstract 492).
    • Hanauer, S., Sandborn, W., Kornbluth, A., Hardi, R., Regalli, G., & Yeh, C. (2005). Delayed-release oral mesalamine 4.8 g/day (800 mg tablet) versus 2.4 g/day (400 mg tablet) for treatment of moderately active ulcerative colitis: combined analysis of two randomised, double-blind, controlled trials. Gastroenterology, 128(4) (Suppl. 2), A-74-75 (Abstract 492).
  • 19
    • 33644653559 scopus 로고    scopus 로고
    • Hanauer, S., Sandborn, W., Kornbluth, A., Katz, S., Safdi, M., Woogen, S., et al. (2005). Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: The ASCEND II trial. American Journal of Gastroenterology, 100, 2478-2485.
    • Hanauer, S., Sandborn, W., Kornbluth, A., Katz, S., Safdi, M., Woogen, S., et al. (2005). Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: The ASCEND II trial. American Journal of Gastroenterology, 100, 2478-2485.
  • 20
    • 39149118880 scopus 로고    scopus 로고
    • Hanauer, S. B., Sandborn, W. J., Dallaire, C., Archambault, A., Yacyshyn, B., Yeh, C., et al. (2007). Efficacy and safety of Asacol 4.8 g/day (800 mg tablets) compared to Asacol 2.4 g/day (400 mg tablets) in the treatment of mild to moderately active ulcerative colitis: The ASCEND I trial. Canadian Journal of Gastroenterology, 21(12), 827-834.
    • Hanauer, S. B., Sandborn, W. J., Dallaire, C., Archambault, A., Yacyshyn, B., Yeh, C., et al. (2007). Efficacy and safety of Asacol 4.8 g/day (800 mg tablets) compared to Asacol 2.4 g/day (400 mg tablets) in the treatment of mild to moderately active ulcerative colitis: The ASCEND I trial. Canadian Journal of Gastroenterology, 21(12), 827-834.
  • 21
    • 85026139949 scopus 로고    scopus 로고
    • Kamm, M. A., Colombel, J. F., Kornbluth, A., Diebold, R., Barrett, K., Karlstadt, R. G., et al. (2007). A randomized comparison of once-versus twice-daily MMX mesalamine for the maintenance of remission in mild-to-moderate ulceratice colitis. Gastroenterology, 132, A-510 (Abstract T1296).
    • Kamm, M. A., Colombel, J. F., Kornbluth, A., Diebold, R., Barrett, K., Karlstadt, R. G., et al. (2007). A randomized comparison of once-versus twice-daily MMX mesalamine for the maintenance of remission in mild-to-moderate ulceratice colitis. Gastroenterology, 132, A-510 (Abstract T1296).
  • 22
    • 33846213645 scopus 로고    scopus 로고
    • Kamm, M. A., Sandborn, W. J., Gassull, M., Schreiber, S., Jackowski, L., Butler, T., et al. (2007). Once-daily high concentration MMX mesalamine in active ulcerative colitis. Gastroenterology, 132(1), 66-75.
    • Kamm, M. A., Sandborn, W. J., Gassull, M., Schreiber, S., Jackowski, L., Butler, T., et al. (2007). Once-daily high concentration MMX mesalamine in active ulcerative colitis. Gastroenterology, 132(1), 66-75.
  • 23
    • 0037245392 scopus 로고    scopus 로고
    • Medication nonadherence and the outcomes of patients with quiescent ulcerative colitis.
    • Kane, S., Huo, D., Aikens, J., & Hanauer, S. (2003). Medication nonadherence and the outcomes of patients with quiescent ulcerative colitis. American Journal of Medicine, 114, 39-43.
    • (2003) American Journal of Medicine , vol.114 , pp. 39-43
    • Kane, S.1    Huo, D.2    Aikens, J.3    Hanauer, S.4
  • 24
    • 0141961614 scopus 로고    scopus 로고
    • A pilot feasibility study of once daily versus conventional dosing mesalamine for maintenance of ulcerative colitis.
    • Kane, S., Huo, D., & Magnanti, K. (2003). A pilot feasibility study of once daily versus conventional dosing mesalamine for maintenance of ulcerative colitis. Clinical Gastroenterology & Hepatology, 1(3), 170-173.
    • (2003) Clinical Gastroenterology Hepatology , vol.1 , Issue.3 , pp. 170-173
    • Kane, S.1    Huo, D.2    Magnanti, K.3
  • 25
    • 0034798909 scopus 로고    scopus 로고
    • Prevalence of nonadherence with maintenance mesalamine in quiescent ulcerative colitis.
    • Kane, S. V., Cohen, R. D., Aikens, J. E., & Hanauer, S. B. (2001). Prevalence of nonadherence with maintenance mesalamine in quiescent ulcerative colitis. American Journal of Gastroenterology, 96(10), 2929-2933.
    • (2001) American Journal of Gastroenterology , vol.96 , Issue.10 , pp. 2929-2933
    • Kane, S.V.1    Cohen, R.D.2    Aikens, J.E.3    Hanauer, S.B.4
  • 26
    • 3843109109 scopus 로고    scopus 로고
    • Ulcerative colitis practice guidelines in adults (update): American College of Gastroenterology, Practice Parameters Committee.
    • Kornbluth, A., & Sachar, D. B. (2004). Ulcerative colitis practice guidelines in adults (update): American College of Gastroenterology, Practice Parameters Committee. American Journal of Gastroenterology, 99(7), 1371-1385.
    • (2004) American Journal of Gastroenterology , vol.99 , Issue.7 , pp. 1371-1385
    • Kornbluth, A.1    Sachar, D.B.2
  • 27
    • 85026134286 scopus 로고    scopus 로고
    • Kruis, W., Gorelov, W., Kludelis, G., Raez, I., Pokrotnieks, J., Horynski, M., et al. (2007). Once daily dosing of 3g mesalamine (Salofalk® granules) is therapeutic equivalent to a three-times daily dosing of 1g mesalamine for the treatment of active ulcerative colitis. Gastroenterology, 132, Abstract 898.
    • Kruis, W., Gorelov, W., Kludelis, G., Raez, I., Pokrotnieks, J., Horynski, M., et al. (2007). Once daily dosing of 3g mesalamine (Salofalk® granules) is therapeutic equivalent to a three-times daily dosing of 1g mesalamine for the treatment of active ulcerative colitis. Gastroenterology, 132, Abstract 898.
  • 28
    • 33846242590 scopus 로고    scopus 로고
    • Lichtenstein, G. R., Kamm, M. A., Boddu, P., Gubergrits, N., Lyne, A., Butler, T., et al. (2007). Effect of once- or twice-daily MMX mesalamine (SPD476) for the induction of remission of mild to moderately active ulcerative colitis. Clinical Gastroenterology & Hepatology, 5, 95-102.
    • Lichtenstein, G. R., Kamm, M. A., Boddu, P., Gubergrits, N., Lyne, A., Butler, T., et al. (2007). Effect of once- or twice-daily MMX mesalamine (SPD476) for the induction of remission of mild to moderately active ulcerative colitis. Clinical Gastroenterology & Hepatology, 5, 95-102.
  • 29
    • 42949096844 scopus 로고    scopus 로고
    • MMX mesalamine for the induction of remission of mild-to-moderately active ulcerative colitis: Efficacy and tolerability in patient sub-populations.
    • Lichtenstein, G. R., Kamm, M. A., Sandborn, W. J., Lyne, A., Butler, T., & Joseph, R. E. (2008). MMX mesalamine for the induction of remission of mild-to-moderately active ulcerative colitis: efficacy and tolerability in patient sub-populations. Alimentary Pharmacology & Therapeutics, 27(11), 1094-1102.
    • (2008) Alimentary Pharmacology Therapeutics , vol.27 , Issue.11 , pp. 1094-1102
    • Lichtenstein, G.R.1    Kamm, M.A.2    Sandborn, W.J.3    Lyne, A.4    Butler, T.5    Joseph, R.E.6
  • 30
    • 4644267065 scopus 로고    scopus 로고
    • Controversies with aminosalicylates in inflammatory bowel disease.
    • Lim, W. C., & Hanauer, S. B. (2004). Controversies with aminosalicylates in inflammatory bowel disease. Review of Gastroenterology Disorders, 4(3), 104-117.
    • (2004) Review of Gastroenterology Disorders , vol.4 , Issue.3 , pp. 104-117
    • Lim, W.C.1    Hanauer, S.B.2
  • 31
    • 33751574430 scopus 로고    scopus 로고
    • A practical perspective on ulcerative colitis: Patients needs from aminosalicylate therapies.
    • Loftus, E. V. (2006). A practical perspective on ulcerative colitis: Patients' needs from aminosalicylate therapies. Inflammatory Bowel Disease, 12(12), 1107-1113.
    • (2006) Inflammatory Bowel Disease , vol.12 , Issue.12 , pp. 1107-1113
    • Loftus, E.V.1
  • 32
    • 85026134540 scopus 로고    scopus 로고
    • Meucci, G., Fasoli, R., Saibeni, S., Valpiani, D., Gullotta, R., Colombo, E., et al. (2006). Prognostic significance of endoscopy remission in patients with active ulcerative colitis treated with oral and topical mesalazine: Preliminary results of a prospective, multicenter study. Gastroenterology, 130, A-197(Abstract S1302).
    • Meucci, G., Fasoli, R., Saibeni, S., Valpiani, D., Gullotta, R., Colombo, E., et al. (2006). Prognostic significance of endoscopy remission in patients with active ulcerative colitis treated with oral and topical mesalazine: Preliminary results of a prospective, multicenter study. Gastroenterology, 130, A-197(Abstract S1302).
  • 33
    • 85026147340 scopus 로고    scopus 로고
    • Retrieved May 16, 2008, from
    • National Digestive Diseases Information Clearinghouse. (2006). Ulcerative colitis.
  • 34
    • 85026152148 scopus 로고    scopus 로고
    • Retrieved May 16, 2008, from
    • Pentasa prescribing information. (2007).
  • 36
    • 11144297984 scopus 로고    scopus 로고
    • Raedler A., Behrens, C., & Bias, P. (2004). Mesalazine (5-aminosalicylic acid) micropellets show similar efficacy and tolerability to mesalazine tablets in patients with ulcerative colitis—results from a randomized-controlled trial. Alimentary Pharmacology & Therapeutics, 20(11/12), 1353-1363.
    • Raedler A., Behrens, C., & Bias, P. (2004). Mesalazine (5-aminosalicylic acid) micropellets show similar efficacy and tolerability to mesalazine tablets in patients with ulcerative colitis—results from a randomized-controlled trial. Alimentary Pharmacology & Therapeutics, 20(11/12), 1353-1363.
  • 37
    • 34250883817 scopus 로고    scopus 로고
    • Multi Matrix System (MMX) mesalazine for the induction of remission in patients with mild-to-moderate ulcerative colitis: A combined analysis of two randomized, double-blind, placebo-controlled trials.
    • Sandborn, W. J., Kamm, M. A., Lichtenstein, G. R., Lyne, A., Butler, T., & Joseph, R. E. (2007). Multi Matrix System (MMX®) mesalazine for the induction of remission in patients with mild-to-moderate ulcerative colitis: a combined analysis of two randomized, double-blind, placebo-controlled trials. Alimentary Pharmacology & Therapeutics, 26(2), 205-215.
    • (2007) Alimentary Pharmacology Therapeutics , vol.26 , Issue.2 , pp. 205-215
    • Sandborn, W.J.1    Kamm, M.A.2    Lichtenstein, G.R.3    Lyne, A.4    Butler, T.5    Joseph, R.E.6
  • 38
    • 26944491174 scopus 로고    scopus 로고
    • Etiology and pathogenesis of inflammatory bowel disease.
    • Schmidt, C., & Stallmach, A. (2005). Etiology and pathogenesis of inflammatory bowel disease. Minerva Gastroenterologica Dietologica, 51(2), 127-145.
    • (2005) Minerva Gastroenterologica Dietologica , vol.51 , Issue.2 , pp. 127-145
    • Schmidt, C.1    Stallmach, A.2
  • 39
    • 0042128396 scopus 로고    scopus 로고
    • Studies of compliance with delayed-release mesalazine therapy in patients with inflammatory bowel disease.
    • Shale, M. J., & Riley S. A. (2003). Studies of compliance with delayed-release mesalazine therapy in patients with inflammatory bowel disease. Alimentary Pharmacology & Therapeutics, 18(2), 191-198.
    • (2003) Alimentary Pharmacology Therapeutics , vol.18 , Issue.2 , pp. 191-198
    • Shale, M.J.1    Riley, S.A.2
  • 40
    • 38449090138 scopus 로고    scopus 로고
    • Release of 5-aminosalicylate from the MMX mesalamine tablet during transit through a simulated gastrointestinal tract system.
    • Tenjarla, S., Romasanta, V., Zeijdner, E., Villa, R., & Moro, L. (2007). Release of 5-aminosalicylate from the MMX™ mesalamine tablet during transit through a simulated gastrointestinal tract system. Advances in Therapy, 24(4), 826-840.
    • (2007) Advances in Therapy , vol.24 , Issue.4 , pp. 826-840
    • Tenjarla, S.1    Romasanta, V.2    Zeijdner, E.3    Villa, R.4    Moro, L.5
  • 41
    • 34250652077 scopus 로고    scopus 로고
    • Take your medicine: Nonadherence issues in patients with ulcerative colitis.
    • Turnbough, L., & Wilson, L. (2007). “Take your medicine”: Nonadherence issues in patients with ulcerative colitis. Gastroenterology Nursing, 30(3), 212-217.
    • (2007) Gastroenterology Nursing , vol.30 , Issue.3 , pp. 212-217
    • Turnbough, L.1    Wilson, L.2
  • 42
    • 25144459131 scopus 로고    scopus 로고
    • 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: A large epidemiological study.
    • van Staa, T. P., Card, T., Logan, R. F., & Leufkens, H. G. (2005). 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: A large epidemiological study. Gut, 54(11), 1573-1578.
    • (2005) Gut , vol.54 , Issue.11 , pp. 1573-1578
    • van Staa, T.P.1    Card, T.2    Logan, R.F.3    Leufkens, H.G.4
  • 43
    • 33744551277 scopus 로고    scopus 로고
    • Velayos, F. S., Loftus, E. V., Jess, T., Harmsen, W. S., Bida, J., Zinsmeister, A. R., et al. (2006). Predictive and protective factors associated with colorectal cancer in ulcerative colitis: A case-control study. Gastroenterology, 130(7), 1941-1949.
    • Velayos, F. S., Loftus, E. V., Jess, T., Harmsen, W. S., Bida, J., Zinsmeister, A. R., et al. (2006). Predictive and protective factors associated with colorectal cancer in ulcerative colitis: A case-control study. Gastroenterology, 130(7), 1941-1949.
  • 44
    • 21344446543 scopus 로고    scopus 로고
    • Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: A systematic review and metaanalysis of observational studies.
    • Velayos, F. S., Terdiman, J. P., & Walsh, J. M. (2005). Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: A systematic review and metaanalysis of observational studies. American Journal of Gastroenterology, 100(6), 1345-1353.
    • (2005) American Journal of Gastroenterology , vol.100 , Issue.6 , pp. 1345-1353
    • Velayos, F.S.1    Terdiman, J.P.2    Walsh, J.M.3
  • 45
    • 0037514407 scopus 로고    scopus 로고
    • Combined scintigraphic and pharmacokinetic investigation of enteric-coated mesalazine micropellets in healthy subjects.
    • Wilding, I., Behrens, C., Tardif, S., Wray, H., Bias, P., & Albrecht, W. (2003). Combined scintigraphic and pharmacokinetic investigation of enteric-coated mesalazine micropellets in healthy subjects. Alimentary Pharmacology & Therapeutics, 17(9), 1153-1162.
    • (2003) Alimentary Pharmacology Therapeutics , vol.17 , Issue.9 , pp. 1153-1162
    • Wilding, I.1    Behrens, C.2    Tardif, S.3    Wray, H.4    Bias, P.5    Albrecht, W.6


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