Cholesterol interactions with fluid-phase phospholipids: Effect on the lateral organization of the bilayer

Biophysical Journal

Volumn 95, Issue 8, 2008, Pages 3861-3871

  Halling, Katrin K ^a   Ramstedt, Bodil ^a   Nyström, Joel H ^a   Slotte, J Peter ^a   Nyholm, Thomas K M ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

1,6 DIPHENYL 1,3,5 HEXATRIENE; 1-PALMITOYL-2-OLEOYLPHOSPHATIDYLCHOLINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; BETA CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; CHOLESTEROL; N OLEOYLSPHINGOMYELIN; N-OLEOYLSPHINGOMYELIN; PALMITOYLSPHINGOMYELIN; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; SPHINGOMYELIN;

ANISOTROPY; ARTICLE; DRUG EFFECT; FLUORESCENCE; LIPID BILAYER; MEMBRANE FLUIDITY; METABOLISM; PHASE TRANSITION;

ANISOTROPY; BETA-CYCLODEXTRINS; CHOLESTEROL; DIPHENYLHEXATRIENE; FLUORESCENCE; LIPID BILAYERS; MEMBRANE FLUIDITY; PHASE TRANSITION; PHOSPHATIDYLCHOLINES; PHOSPHOLIPIDS; SPHINGOMYELINS;

EID: 56049095508     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1529/biophysj.108.133744     Document Type: Article

References (42)

1. Zeyda, M., and T. M. Stulnig. 2006. Lipid Rafts & Co.: an integrated model of membrane organization in T cell activation. Prog. Lipid Res. 45:187-202.
2. Hanzal-Bayer, M. F., and J. F. Hancock. 2007. Lipid rafts and membrane traffic. FEBS Lett. 581:2098-2104.
3. Ipsen, J. H., G. Karlstrom, O. G. Mouritsen, H. Wennerstrom, and M. J. Zuckermann. 1987. Phase equilibria in the phosphatidylcholine-cholesterol system. Biochim. Biophys. Acta. 905:162-172.
4. Feigenson, G. W. 2007. Phase boundaries and biological membranes. Annu. Rev. Biophys. Biomol. Struct. 36:63-77.
5. van Meer, G., D. R. Voelker, and G. W. Feigenson. 2008. Membrane lipids: where they are and how they behave. Nat. Rev. 9:112-124.
6. Bunge, A., P. Muller, M. Stockel, A. Herrmann, and D. Huster. 2008. Characterization of the ternary mixture of sphingomyelin, POPC, and cholesterol: support for an inhomogeneous lipid distribution at high temperatures. Biophys. J. 94:2680-2690.
7. de Almeida, R. F., A. Fedorov, and M. Prieto. 2003. Sphingomyelin/ phosphatidylcholine/cholesterol phase diagram: boundaries and composition of lipid rafts. Biophys. J. 85:2406-2416.
8. de Almeida, R. F., L. M. Loura, A. Fedorov, and M. Prieto. 2005. Lipid rafts have different sizes depending on membrane composition: a time-resolved fluorescence resonance energy transfer study. J. Mol. Biol. 346:1109-1120.
9. Garcia-Saez, A. J., S. Chiantia, and P. Schwille. 2007. Effect of line tension on the lateral organization of lipid membranes. J. Biol. Chem. 282:33537-33544.
10. Veatch, S. L., and S. L. Keller. 2003. Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol. Biophys. J. 85:3074-3083.
11. Kariel, N., E. Davidson, and K. M. Keough. 1991. Cholesterol does not remove the gel-liquid crystalline phase transition of phosphatidylcholines containing two polyenoic acyl chains. Biochim. Biophys. Acta. 1062:70-76.
12. Litman, B. J., E. N. Lewis, and I. W. Levin. 1991. Packing characteristics of highly unsaturated bilayer lipids: Raman spectroscopic studies of multilamellar phosphatidylcholine dispersions. Biochemistry. 30:313-319.
13. Shaikh, S. R., A. C. Dumaual, A. Castillo, D. LoCascio, R. A. Siddiqui, W. Stillwell, and S. R. Wassall. 2004. Oleic and docosahexaenoic acid differentially phase separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study. Biophys. J. 87:1752-1766.
14. Filippov, A., G. Oradd, and G. Lindblom. 2007. Domain formation in model membranes studied by pulsed-field gradient-NMR: the role of lipid polyunsaturation. Biophys. J. 93:3182-3190.
15. Bakht, O., P. Pathak, and E. London. 2007. Effect of the structure of lipids favoring disordered domain formation on the stability of cholesterol-containing ordered domains (lipid rafts): identification of multiple raft-stabilization mechanisms. Biophys. J. 93:4307-4318.
16. Sklar, L. A., B. S. Hudson, and R. D. Simoni. 1977. Conjugated polyene fatty acids as fluorescent probes: synthetic phospholipid membrane studies. Biochemistry. 16:819-828.
17. Sklar, L. A., B. S. Hudson, M. Petersen, and J. Diamond. 1977. Conjugated polyene fatty acids on fluorescent probes: spectroscopic characterization. Biochemistry. 16:813-819.
18. Niu, S. L., and B. J. Litman. 2002. Determination of membrane cholesterol partition coefficient using a lipid vesicle-cyclodextrin binary system: effect of phospholipid acyl chain unsaturation and headgroup composition. Biophys. J. 83:3408-3415.
19. Tsamaloukas, A., H. Szadkowska, P. J. Slotte, and H. Heerklotz. 2005. Interactions of cholesterol with lipid membranes and cyclodextrin characterized by calorimetry. Biophys. J. 89:1109-1119.
20. Lakowicz, J. R. 1999. Principles of Fluorescence Spectroscopy. Kluvert Academic/Plenum Publishers, New York.
21. Leventis, R., and J. R. Silvius. 2001. Use of cyclodextrins to monitor transbilayer movement and differential lipid affinities of cholesterol. Biophys. J. 81:2257-2267.
22. Ohvo-Rekila, H., B. Akerlund, and J. P. Slotte. 2000. Cyclodextrin-catalyzed extraction of fluorescent sterols from monolayer membranes and small unilamellar vesicles. Chem. Phys. Lipids. 105:167-178.
23. Ohvo-Rekila, H., B. Ramstedt, P. Leppimaki, and J. P. Slotte. 2002. Cholesterol interactions with phospholipids in membranes. Prog. Lipid Res. 41:66-97.
24. Ramstedt, B., and J. P. Slotte. 1999. Interaction of cholesterol with sphingomyelins and acyl-chain-matched phosphatidylcholines: a comparative study of the effect of the chain length. Biophys. J. 76:908-915.
25. Curatolo, W., B. Sears, and L. J. Neuringer. 1985. A calorimetry and deuterium NMR study of mixed model membranes of 1-palmitoyl-2- oleylphosphatidylcholine and saturated phosphatidylcholines. Biochim. Biophys. Acta. 817:261-270.
26. Mateo, C. R., J. C. Brochon, M. P. Lillo, and A. U. Acuna. 1993. Lipid clustering in bilayers detected by the fluorescence kinetics and anisotropy of trans-parinaric acid. Biophys. J. 65:2237-2247.
27. Silva, L. C., R. F. de Almeida, B. M. Castro, A. Fedorov, and M. Prieto. 2007. Ceramide-domain formation and collapse in lipid rafts: membrane reorganization by an apoptotic lipid. Biophys. J. 92:502-516.
28. Sklar, L. A., G. P. Miljanich, and E. A. Dratz. 1979. Phospholipid lateral phase separation and the partition of cis-parinaric acid and trans-parinaric acid among aqueous, solid lipid, and fluid lipid phases. Biochemistry. 18:1707-1716.
29. Tsamaloukas, A., H. Szadkowska, and H. Heerklotz. 2006. Thermodynamic comparison of the interactions of cholesterol with unsaturated phospholipid and sphingomyelins. Biophys. J. 90:4479-4487.
30. Radhakrishnan, A., and H. M. McConnell. 1999. Condensed complexes of cholesterol and phospholipids. Biophys. J. 77:1507-1517.
31. McConnell, H. M., and A. Radhakrishnan. 2003. Condensed complexes of cholesterol and phospholipids. Biochim. Biophys. Acta. 1610:159-173.
32. Epand, R. M. 2003. Cholesterol in bilayers of sphingomyelin or dihydrosphingomyelin at concentrations found in ocular lens membranes. Biophys. J. 84:3102-3110.
33. Epand, R. M., and R. F. Epand. 2004. Non-raft forming sphingomyelin-cholesterol mixtures. Chem. Phys. Lipids. 132:37-46.
34. Huang, J., and G. W. Feigenson. 1999. A microscopic interaction model of maximum solubility of cholesterol in lipid bilayers. Biophys. J. 76:2142-2157.
35. Aittoniemi, J., P. S. Niemela, M. T. Hyvonen, M. Karttunen, and I. Vattulainen. 2007. Insight into the putative specific interactions between cholesterol, sphingomyelin, and palmitoyl-oleoyl phosphatidylcholine. Biophys. J. 92:1125-1137.
36. Veatch, S. L., K. Gawrisch, and S. L. Keller. 2006. Closed-loop miscibility gap and quantitative tie-lines in ternary membranes containing diphytanoyl PC. Biophys. J. 90:4428-4436.
37. Zhao, J., J. Wu, F. A. Heberle, T. T. Mills, P. Klawitter, G. Huang, G. Costanza, and G. W. Feigenson. 2007. Phase studies of model biomembranes: complex behavior of DSPC/DOPC/cholesterol. Biochim. Biophys. Acta. 1768:2764-2776.
38. Veatch, S. L., and S. L. Keller. 2005. Miscibility phase diagrams of giant vesicles containing sphingomyelin. Phys. Rev. Lett. 94:148101.
39. Heerklotz, H., and A. Tsamaloukas. 2006. Gradual change or phase transition: characterizing fluid lipid-cholesterol membranes on the basis of thermal volume changes. Biophys. J. 91:600-607.
40. Mateo, C. R., A. U. Acuna, and J. C. Brochon. 1995. Liquid-crystalline phases of cholesterol lipid bilayers as revealed by the fluorescence of trans-parinaric acid. Biophys. J. 68:978-987.
41. Thewalt, J. L., and M. Bloom. 1992. Phosphatidylcholine-cholesterol phase-diagrams. Biophys. J. 63:1176-1181.
42. Zhang, Z., S. Y. Bhide, and M. L. Berkowitz. 2007. Molecular dynamics simulations of bilayers containing mixtures of sphingomyelin with cholesterol and phosphatidylcholine with cholesterol. J. Phys. Chem. 111:12888-12897.