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Volumn 23, Issue 5, 2008, Pages 833-837

Low frequency and variability of FLT3 mutations in Korean patients with acute myeloid leukemia

Author keywords

FLT3 mutations; Internal tandem duplication; Leukemia, myeloid, acute; Tyrosine kinase domain mutation

Indexed keywords

CD135 ANTIGEN;

EID: 56049091809     PISSN: 10118934     EISSN: 15986357     Source Type: Journal    
DOI: 10.3346/jkms.2008.23.5.833     Document Type: Article
Times cited : (14)

References (32)
  • 2
    • 16944365287 scopus 로고    scopus 로고
    • Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodyplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines
    • Yokota S, Kiyoi H, Nakao M, Iwai T, Misawa S, Okuda T, Sonoda Y, Abe T, Kahsima K, Matsuo Y, Naoe T. Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodyplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines. Leukemia 1997; 11: 1605-9.
    • (1997) Leukemia , vol.11 , pp. 1605-1609
    • Yokota, S.1    Kiyoi, H.2    Nakao, M.3    Iwai, T.4    Misawa, S.5    Okuda, T.6    Sonoda, Y.7    Abe, T.8    Kahsima, K.9    Matsuo, Y.10    Naoe, T.11
  • 3
    • 0036020954 scopus 로고    scopus 로고
    • FLT3 in human hematologic malignancies
    • Kiyoi H, Naoe T. FLT3 in human hematologic malignancies. Leuk Lymphoma 2002; 43: 1541-7.
    • (2002) Leuk Lymphoma , vol.43 , pp. 1541-1547
    • Kiyoi, H.1    Naoe, T.2
  • 6
    • 0036839326 scopus 로고    scopus 로고
    • A new recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia
    • Spiekermann K, Bagrintseva K, Schoch C, Haferlach T, Hiddemann W, Schnittger S. A new recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia. Blood 2002; 100: 3423-5.
    • (2002) Blood , vol.100 , pp. 3423-3425
    • Spiekermann, K.1    Bagrintseva, K.2    Schoch, C.3    Haferlach, T.4    Hiddemann, W.5    Schnittger, S.6
  • 7
    • 0141465061 scopus 로고    scopus 로고
    • The role of FLT3 in haematopoietic malignancies
    • Stirewalt DL, Radich JP. The role of FLT3 in haematopoietic malignancies. Nat Rev Cancer 2003; 3: 650-65.
    • (2003) Nat Rev Cancer , vol.3 , pp. 650-665
    • Stirewalt, D.L.1    Radich, J.P.2
  • 10
    • 0036736501 scopus 로고    scopus 로고
    • Boissel N, Cayuela JM, Preudhomme C, Thomas X, Grardel N, Fund X, Tigaud I, Raffoux E, Rousselot P, Sigaux F, Degos L, Castaigne S, Fenaux P, Dombret H. Prognostic significance of FLT3 internal tandem repeat in patients with de novo acute myeloid leukemia treated with reinforced courses of chemotherapy. Leukemia 2002; 16: 1699-704.
    • Boissel N, Cayuela JM, Preudhomme C, Thomas X, Grardel N, Fund X, Tigaud I, Raffoux E, Rousselot P, Sigaux F, Degos L, Castaigne S, Fenaux P, Dombret H. Prognostic significance of FLT3 internal tandem repeat in patients with de novo acute myeloid leukemia treated with reinforced courses of chemotherapy. Leukemia 2002; 16: 1699-704.
  • 11
    • 0035885955 scopus 로고    scopus 로고
    • The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
    • Kottaridis PD, Gale RE, Frew ME, Harrison G, Langabeer SE, Belton AA, Walker H, Wheatley K, Bowen DT, Burnett AK, Goldstone AH, Linch DC. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood 2001; 98: 1752-9.
    • (2001) Blood , vol.98 , pp. 1752-1759
    • Kottaridis, P.D.1    Gale, R.E.2    Frew, M.E.3    Harrison, G.4    Langabeer, S.E.5    Belton, A.A.6    Walker, H.7    Wheatley, K.8    Bowen, D.T.9    Burnett, A.K.10    Goldstone, A.H.11    Linch, D.C.12
  • 13
    • 0036659931 scopus 로고    scopus 로고
    • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: Correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
    • Schnittger S, Schoch C, Dugas M, Kern W, Staib P, Wuchter C, Loffler H, Sauerland CM, Serve H, Buchner T, Haferlach T, Hiddemann W. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood 2002; 100: 59-66.
    • (2002) Blood , vol.100 , pp. 59-66
    • Schnittger, S.1    Schoch, C.2    Dugas, M.3    Kern, W.4    Staib, P.5    Wuchter, C.6    Loffler, H.7    Sauerland, C.M.8    Serve, H.9    Buchner, T.10    Haferlach, T.11    Hiddemann, W.12
  • 14
    • 56049113031 scopus 로고    scopus 로고
    • The presence of FLT3/ITD mutations is an independent prognostic factor in acute myeloid leukemia patients with normal karyotype
    • Kim YK, Lee JJ, Lee YR, Lee IK Kim HN, Kim NY, Park KS, Yang DH, Park MR, Kim HJ. The presence of FLT3/ITD mutations is an independent prognostic factor in acute myeloid leukemia patients with normal karyotype. Blood 2004; 104: 3008a.
    • (2004) Blood , vol.104
    • Kim, Y.K.1    Lee, J.J.2    Lee, Y.R.3    Lee, I.K.4    Kim, H.N.5    Kim, N.Y.6    Park, K.S.7    Yang, D.H.8    Park, M.R.9    Kim, H.J.10
  • 16
    • 18044394180 scopus 로고    scopus 로고
    • Prognostic significance of FLT3 mutations in pediatric nonpromyelocytic acute myeloid leukemia
    • Kang HJ, Hong SH, Kim IH, Park BK, Han KS, Cho HI, Shin HY, Ahn HS. Prognostic significance of FLT3 mutations in pediatric nonpromyelocytic acute myeloid leukemia. Leuk Res 2005; 29: 617-23.
    • (2005) Leuk Res , vol.29 , pp. 617-623
    • Kang, H.J.1    Hong, S.H.2    Kim, I.H.3    Park, B.K.4    Han, K.S.5    Cho, H.I.6    Shin, H.Y.7    Ahn, H.S.8
  • 17
    • 0033043084 scopus 로고    scopus 로고
    • Molecular evolution of acute myeloid leukaemia in relapse: Unstable N-ras and FLT3 genes compared with p53 gene
    • Nakano Y, Kiyoi H, Miyawaki S, Asou N, Ohno R, Saito H, Naoe T. Molecular evolution of acute myeloid leukaemia in relapse: unstable N-ras and FLT3 genes compared with p53 gene. Br J Haematol 1999; 104: 659-64.
    • (1999) Br J Haematol , vol.104 , pp. 659-664
    • Nakano, Y.1    Kiyoi, H.2    Miyawaki, S.3    Asou, N.4    Ohno, R.5    Saito, H.6    Naoe, T.7
  • 18
    • 33751284416 scopus 로고    scopus 로고
    • Favourable prognosis associated with FLT3 tyrosine kinase domain mutations in AML in contrast to the adverse outcome associated with internal tandem duplications
    • Mead A, Linch D, Hills R, Wheatley K, Burnett A, Gale R. Favourable prognosis associated with FLT3 tyrosine kinase domain mutations in AML in contrast to the adverse outcome associated with internal tandem duplications. Blood 2005; 106: 334a.
    • (2005) Blood , vol.106
    • Mead, A.1    Linch, D.2    Hills, R.3    Wheatley, K.4    Burnett, A.5    Gale, R.6
  • 19
    • 0036786289 scopus 로고    scopus 로고
    • Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: A comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse
    • Shih LY, Huang CF, Wu JH, Lin TL, Dunn P, Wang PN, Kuo MC, Lai CL, Hsu HC. Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse. Blood 2002; 100: 2387-92.
    • (2002) Blood , vol.100 , pp. 2387-2392
    • Shih, L.Y.1    Huang, C.F.2    Wu, J.H.3    Lin, T.L.4    Dunn, P.5    Wang, P.N.6    Kuo, M.C.7    Lai, C.L.8    Hsu, H.C.9
  • 20
    • 0036786601 scopus 로고    scopus 로고
    • Acute myelogenous leukemia with internal tandem duplication of the Flt3 gene appearing or altering at the time of relapse: A report of two cases
    • Hovland R, Gjertsen BT, Bruserud O. Acute myelogenous leukemia with internal tandem duplication of the Flt3 gene appearing or altering at the time of relapse: a report of two cases. Leuk Lymphoma 2002; 43: 2027-9.
    • (2002) Leuk Lymphoma , vol.43 , pp. 2027-2029
    • Hovland, R.1    Gjertsen, B.T.2    Bruserud, O.3
  • 23
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial. The medical research council adult and children's leukaemia working parties
    • Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, Harrison G, Rees J, Hann I, Stevens R, Burnett A, Goldstone A. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The medical research council adult and children's leukaemia working parties. Blood 1998; 92: 2322-33.
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3    Wheatley, K.4    Harrison, C.5    Harrison, G.6    Rees, J.7    Hann, I.8    Stevens, R.9    Burnett, A.10    Goldstone, A.11
  • 24
    • 27644476367 scopus 로고    scopus 로고
    • Analysis of FLT3 internal tandem duplication and D835 mutations in Chinese acute leukemia patients
    • Wang L, Lin D, Zhang X, Chen S, Wang M, Wang J. Analysis of FLT3 internal tandem duplication and D835 mutations in Chinese acute leukemia patients. Leuk Res 2005; 29: 1393-8.
    • (2005) Leuk Res , vol.29 , pp. 1393-1398
    • Wang, L.1    Lin, D.2    Zhang, X.3    Chen, S.4    Wang, M.5    Wang, J.6
  • 25
    • 33750485843 scopus 로고    scopus 로고
    • Inferior prognostic outcome in acute promyelocytic leukemia with alteration of FLT3 gene
    • Yoo SJ, Park CJ, Jang S, Seo EJ, Lee KH, Chi HS. Inferior prognostic outcome in acute promyelocytic leukemia with alteration of FLT3 gene. Leuk Lymphoma 2006; 47: 1788-93.
    • (2006) Leuk Lymphoma , vol.47 , pp. 1788-1793
    • Yoo, S.J.1    Park, C.J.2    Jang, S.3    Seo, E.J.4    Lee, K.H.5    Chi, H.S.6
  • 26
    • 33750446513 scopus 로고    scopus 로고
    • Analysis of FLT3-activiating mutations in 77 patients with acute myelogenous leukemia; association with WHO classification
    • Kong SY, Ki CS, Lee SG, Hong SA, Kim JW, Kim SH. Analysis of FLT3-activiating mutations in 77 patients with acute myelogenous leukemia; association with WHO classification. Korean J Hematol 2003; 38: 44a.
    • (2003) Korean J Hematol , vol.38
    • Kong, S.Y.1    Ki, C.S.2    Lee, S.G.3    Hong, S.A.4    Kim, J.W.5    Kim, S.H.6
  • 31
    • 13244272253 scopus 로고    scopus 로고
    • Therapeutic intervention in leukemias that express the activated fms-like tyrosine kinase 3 (FLT3): Opportunities and challenges
    • Sternberg DW, Licht JD. Therapeutic intervention in leukemias that express the activated fms-like tyrosine kinase 3 (FLT3): opportunities and challenges. Curr Opin Hematol 2005; 12: 7-13.
    • (2005) Curr Opin Hematol , vol.12 , pp. 7-13
    • Sternberg, D.W.1    Licht, J.D.2
  • 32
    • 24944447981 scopus 로고    scopus 로고
    • Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia
    • Kuchenbauer F, Schoch C, Kern W, Hiddemann W, Haferlach T, Schnittger S. Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia. Br J Haematol 2005; 130: 196-202.
    • (2005) Br J Haematol , vol.130 , pp. 196-202
    • Kuchenbauer, F.1    Schoch, C.2    Kern, W.3    Hiddemann, W.4    Haferlach, T.5    Schnittger, S.6


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