NADPH oxidase-mediated generation of reactive oxygen species: A new mechanism for X-ray-induced HeLa cell death

Biochemical and Biophysical Research Communications

Volumn 377, Issue 3, 2008, Pages 775-779

  Liu, Qing ^a,b   He, Xiaoqing ^c   Liu, Yongsheng ^d   Du, Bingbing ^c   Wang, Xiaoyan ^c   Zhang, Weisheng ^e   Jia, Pengfei ^c   Dong, Jingmei ^f   Ma, Jianxiu ^g   Wang, Xiaohu ^h   Li, Sha ⁱ   Zhang, Hong ^a,b  

^a INSTITUTE OF MODERN PHYSICS   (China)

^b Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province   (China)

^c LANZHOU UNIVERSITY   (China)

^d AGRO ENVIRONMENTAL PROTECTION INSTITUTE   (China)

^e GANSU PROVINCIAL HOSPITAL   (China)

^f LANZHOU CITY UNIVERSITY   (China)

^g NORTH MINZU UNIVERSITY   (China)

^h Gansu Cancer Hospital   (China)

ⁱ LANZHOU GENERAL HOSPITAL   (China)

Author keywords

HeLa cell death; NADPH oxidase; New mechanism; X ray irradiation

Indexed keywords

GLYCOPROTEIN GP 91; PROTEIN P22; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ARTICLE; CANCER RADIOTHERAPY; CELL DEATH; CELL MEMBRANE; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; GENE TRANSFER; HELA CELL; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RADIOLYSIS; UPREGULATION; X IRRADIATION;

APOPTOSIS; GENE THERAPY; HELA CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; NEOPLASMS; RADIATION TOLERANCE; REACTIVE OXYGEN SPECIES; X-RAYS;

EID: 56049089797     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.067     Document Type: Article

References (17)

1. Chapman J.D., Reuvers A.P., Borsa J., and Greenstock C.L. Chemical radioprotection and radiosensitization of mammalian cells growing in vitro. Radiat. Res. 56 (1973) 291-306
2. Roots R., and Okada S. Estimation of life times and diffusion distances of radicals involved in X-ray-induced DNA strand breaks or killing of mammalian cells. Radiat. Res. 64 (1975) 306-320
3. Tolando R., Jovanovic A., Brigelius-Flohe R., Ursini F., and Maiorino M. Reactive oxygen species and proinflammatory cytokine signaling in endothelial cells: effect of selenium supplementation. Free Radic. Biol. Med. 28 (2000) 979-986
4. Kim Y.H., and Koh J.Y. The role of NADPH oxidase and neuronal nitric oxide synthase in zinc-induced poly(ADP-ribose) polymerase activation and cell death in cortical culture. Exp. Neurol. 177 (2002) 407-418
5. Roberts C.K., Barnard R.J., Sindhu R.K., Jurczak M., Ehdaie A., and Vaziri N.D. Oxidative stress and dysregulation of NAD(P)H oxidase and antioxidant enzymes in diet-induced metabolic syndrome. Metabolism 55 (2006) 928-934
6. Valencia A., Rajadurai A., Carle A.B., and Kochevar I.E. 7-Dehydrocholesterol enhances ultraviolet A-induced oxidative stress in keratinocytes: roles of NADPH oxidase, mitochondria, and lipid rafts. Free Radic. Biol. Med. 41 (2006) 1704-1718
7. Yang S., Madyastha P., Bingel S., Ries W., and Key L.A. New superoxide-generating oxidase in murine osteoclasts. J. Biol. Chem. 276 (2001) 5452-5458
8. Liu Q., Kang J.H., and Zheng R.L. NADPH oxidase produces reactive oxygen species and maintains survival of rat astrocytes. Cell Biochem. Funct. 23 (2005) 93-100
9. Duranteau J., Chandel N.S., Kulisz A., Shao Z., and Schumacker P.T. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J. Biol. Chem. 273 (1998) 11619-11624
10. Leusen J.H., Verhoeven A.J., and Roos D. Interactions between the components of the human NADPH oxidase: intrigues in the phox family. J. Lab. Clin. Med. 128 (1996) 461-476
11. Johnson J.L., Park J.W., Benna J.E., Faust L.P., Inanami O., and Babior B.M. Activation of p47(PHOX), a cytosolic subunit of the leukocyte NADPH oxidase. Phosphorylation of ser-359 or ser-370 precedes phosphorylation at other sites and is required for activity. J. Biol. Chem. 273 (1998) 35147-35152
12. Kerimoglu U., Akata D., Hazirolan T., Ergen F.B., Köse F., Ozyar E., Atahan L.I., and Akhan O. Evaluation of radiotherapy response of cervical carcinoma with gray scale and color Doppler ultrasonography: resistive index correlation with magnetic resonance findings. Diagn. Interv. Radiol. 12 (2006) 155-160
13. Appold S., Baumann M., Petersen C., Horn K., and Eichhorn F. Comparison of the response of human FaDu squamous cell carcinoma in nude mice after hypofractionated-accelerated regimens and "curative" fractionation schedules. Strahlenther. Onkol. 174 (1998) 315-319
14. Hermann R.M., Fest J., Christiansen H., Hille A., Rave-Fränk M., Nitsche M., Gründker C., Viereck V., Jarry H., and Schmidberger H. Radiosensitization dependent on p53 function in bronchial carcinoma cells by the isoflavone genistein and estradiol in vitro. Strahlenther. Onkol. 183 (2007) 195-202
15. Pappas G., Zumstein L.A., Munshi A., Hobbs M., and Meyn R.E. Adenoviral-mediated PTEN expression radiosensitizes non-small cell lung cancer cells by suppressing DNA repair capacity. Cancer Gene Ther. 14 (2007) 543-549
16. Rhee J.G., Li D., Suntharalingam M., Guo C., O'Malley B.W., and Carney J.P. Radiosensitization of head/neck squamous cell carcinoma by adenovirus-mediated expression of the Nbs1 protein. Int. J. Radiat. Oncol. Biol. Phys. 67 (2007) 273-278
17. McCarthy H.O., Worthington J., Barrett E., Cosimo E., Boyd M., Mairs R.J., Ward C., McKeown S.R., Hirst D.G., and Robson T. p21((WAF1))-mediated transcriptional targeting of inducible nitric oxide synthase gene therapy sensitizes tumours to fractionated radiotherapy. Gene Ther. 14 (2007) 246-255