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Volumn 8, Issue 2, 2008, Pages 141-146

The genotoxicity of vitamin c in vitro

Author keywords

Chromosome abnormalities; Human lymphocytes; Vitamin C (ascorbic acid)

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; COLCHICINE; MUTAGENIC AGENT;

EID: 55949130092     PISSN: 15128601     EISSN: None     Source Type: Journal    
DOI: 10.17305/bjbms.2008.2969     Document Type: Article
Times cited : (11)

References (25)
  • 1
    • 0021354607 scopus 로고
    • Genetic toxicology of ascorbic acid
    • Shamberger R.J. Genetic toxicology of ascorbic acid. Mutat. Res. 1984; 133:135-159.
    • (1984) Mutat. Res. , vol.133 , pp. 135-159
    • Shamberger, R.J.1
  • 2
    • 0030044435 scopus 로고    scopus 로고
    • Antioxidant defenses against reactive oxygen species causing genetic and other damage
    • Anderson D. Antioxidant defenses against reactive oxygen species causing genetic and other damage. Mutat. Res. 1996; 350:103-108.
    • (1996) Mutat. Res. , vol.350 , pp. 103-108
    • Anderson, D.1
  • 3
    • 0030894953 scopus 로고    scopus 로고
    • Vitamins as antimutagens: Advantages and some possible mechanisms of antimutagenic action
    • Odin A.P. Vitamins as antimutagens: Advantages and some possible mechanisms of antimutagenic action. Mutat. Res. 1997; 386:39-67.
    • (1997) Mutat. Res. , vol.386 , pp. 39-67
    • Odin, A.P.1
  • 5
    • 0032953235 scopus 로고    scopus 로고
    • Protection and Induction of Chromosomal Damage by Vitamin C in Human Lymphocyte Cultures
    • Antunes L.M.G., Takahashi C.S. Protection and Induction of Chromosomal Damage by Vitamin C in Human Lymphocyte Cultures. Teratog., Carcinog., Mutagen. 1999; 19:53-59.
    • (1999) Teratog., Carcinog., Mutagen , vol.19 , pp. 53-59
    • Antunes, L.M.G.1    Takahashi, C.S.2
  • 6
    • 0035889596 scopus 로고    scopus 로고
    • Anticlastogenic effect of vitamin C on cisplatin induced chromosome aberrations in human lymphocyte cultures
    • Nefic H. Anticlastogenic effect of vitamin C on cisplatin induced chromosome aberrations in human lymphocyte cultures. Mutat. Res. 2001; 49 8:89-9 8.
    • (2001) Mutat. Res. , vol.498 , pp. 89-98
    • Nefic, H.1
  • 7
    • 0018885770 scopus 로고
    • The SCE-inducing capacity of vitamin C: investigations in vitro and in vivo.
    • Speit G., Wolf M., Vogel W. The SCE-inducing capacity of vitamin C: investigations in vitro and in vivo. Mutat. Res.1980; 78:273-278.
    • (1980) Mutat. Res , vol.78 , pp. 273-278
    • Speit, G.1    Wolf, M.2    Vogel, W.3
  • 8
    • 0028147174 scopus 로고
    • Effect of diet and vitamin C on DNA strand breakage in freshly-isolated human white blood cells
    • Green M.H.L., Lowe J.E., Waugh A.P.W., Aldridge K.E., Cole J., Arlett C.F. Effect of diet and vitamin C on DNA strand breakage in freshly-isolated human white blood cells. Mutat. Res. 1994; 316:91-102.
    • (1994) Mutat. Res. , vol.316 , pp. 91-102
    • Green, M.H.L.1    Lowe, J.E.2    Waugh, A.P.W.3    Aldridge, K.E.4    Cole, J.5    Arlett, C.F.6
  • 9
    • 0028305534 scopus 로고
    • The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay
    • Anderson D., Yu T.-W., Phillips B.J., Schmezer P. The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the COMET assay. Mutat. Res. 1994; 307:261-271.
    • (1994) Mutat. Res. , vol.307 , pp. 261-271
    • Anderson, D.1    Yu, T.-W.2    Phillips, B.J.3    Schmezer, P.4
  • 10
    • 0018393389 scopus 로고
    • Vitamin C is positive in the DNA synthesis inhibition and sister-chromatid exchange tests
    • Galloway S.M., Painter R.B. Vitamin C is positive in the DNA synthesis inhibition and sister-chromatid exchange tests. Mutat. Res. 1979:60:321-327.
    • (1979) Mutat. Res. , vol.60 , pp. 321-327
    • Galloway, S.M.1    Painter, R.B.2
  • 11
    • 0029025436 scopus 로고
    • The effect of antioxidants on bleomycin treatment in in vitro and in vivo geno- toxicity assays
    • Anderson D., Basaran N., Blowers S.D., Edwards A.J. The effect of antioxidants on bleomycin treatment in in vitro and in vivo geno- toxicity assays. Mutat. Res. 1995; 329:37-47.
    • (1995) Mutat. Res. , vol.329 , pp. 37-47
    • Anderson, D.1    Basaran, N.2    Blowers, S.D.3    Edwards, A.J.4
  • 13
    • 0032500996 scopus 로고    scopus 로고
    • Effects of high doses of vitamins C and E against doxorubicin-induced chromosomal damage in Wistar rat bone marrow cells
    • Antunes L.M.G., Takahashi C.S. Effects of high doses of vitamins C and E against doxorubicin-induced chromosomal damage in Wistar rat bone marrow cells. Mutat. Res. 1998; 419:137-143.
    • (1998) Mutat. Res. , vol.419 , pp. 137-143
    • Antunes, L.M.G.1    Takahashi, C.S.2
  • 16
    • 0032480774 scopus 로고    scopus 로고
    • Vitamin C medited protection on cisplatin-induced mutagenicity in mice
    • Giri A., Khynriam D., Prasad S.B. Vitamin C medited protection on cisplatin-induced mutagenicity in mice. Mutat. Res. 1998; 421:139-148.
    • (1998) Mutat. Res. , vol.421 , pp. 139-148
    • Giri, A.1    Khynriam, D.2    Prasad, S.B.3
  • 17
    • 0342879897 scopus 로고    scopus 로고
    • Effects of the antioxidants curcumin and vitamin C on cisplatin-induced clastogenesis in Wistar rat bone marrow cells
    • Antunes L.M.G., Araújo M.C.P., Darin J.D.C., Bianchi M.L.P. Effects of the antioxidants curcumin and vitamin C on cisplatin-induced clastogenesis in Wistar rat bone marrow cells. Mutat. Res. 2000:465:131-137.
    • (2000) Mutat. Res. , vol.465 , pp. 131-137
    • Antunes, L.M.G.1    Araújo, M.C.P.2    Darin, J.D.C.3    Bianchi, M.L.P.4
  • 18
    • 0026574230 scopus 로고
    • Effects of L-ascorbic acid on the mutagenicity of ethyl methanesulfonate in cultured mammalian cells
    • Kojima H., Konishi H., Kuroda Y. Effects of L-ascorbic acid on the mutagenicity of ethyl methanesulfonate in cultured mammalian cells. Mutat. Res. 1992; 266:85-91.
    • (1992) Mutat. Res. , vol.266 , pp. 85-91
    • Kojima, H.1    Konishi, H.2    Kuroda, Y.3
  • 19
    • 0022529472 scopus 로고
    • Inhibition of cyclophosphamide and mitomycin C-induced sister chromatid exchanges in mice by vitamin C
    • Krishna G., Nath J., Ong,T. Inhibition of cyclophosphamide and mitomycin C-induced sister chromatid exchanges in mice by vitamin C. Cancer Res. 1986; 46:2670-2674.
    • (1986) Cancer Res. , vol.46 , pp. 2670-2674
    • Krishna, G.1    Nath, J.2    Ong, T.3
  • 20
    • 0000469330 scopus 로고
    • Antimutagenic activity of vitamins in cultured mammalian cells
    • In: Kuroda Y., Shankel D.M., Waters M.D. (eds),. Plenum Press, New York
    • Kuroda Y. Antimutagenic activity of vitamins in cultured mammalian cells. In: Kuroda Y., Shankel D.M., Waters M.D. (eds), An-timutagenesis and Anticarcinogenesis Mechanisms II. Plenum Press, New York, 1990.
    • (1990) An-timutagenesis and Anticarcinogenesis Mechanisms II
    • Kuroda, Y.1
  • 21
    • 13344283430 scopus 로고    scopus 로고
    • Protective effects of a-hederin, chlorophillin and ascorbic acid towards the induction of micronuclei by dox-orubicin in cultured human lymphocytes
    • Amara-Mokrane Y.A., Lebucher-Michel M.P., Balansard G., Du-m?nil G., Botta B. Protective effects of a-hederin, chlorophillin and ascorbic acid towards the induction of micronuclei by dox-orubicin in cultured human lymphocytes. Mutagenesis. 1996; 11:161-167.
    • (1996) Mutagenesis , vol.11 , pp. 161-167
    • Amara-Mokrane, Y.A.1    Lebucher-Michel, M.P.2    Balansard, G.3    Du-ménil, G.4    Botta, B.5
  • 23
    • 0021972002 scopus 로고
    • Biological nature of the effect of ascorbic acids on the growth of human leukemic cells
    • Park C.H. Biological nature of the effect of ascorbic acids on the growth of human leukemic cells. Cancer Res. 1985; 45:3969-3973-
    • (1985) Cancer Res. , vol.45 , pp. 3969-3973
    • Park, C.H.1
  • 24
    • 0031004137 scopus 로고    scopus 로고
    • Ascorbic acid and 6-deoxy-6-chloro-ascorbic acid: potential anticancer drugs
    • Osmak M., Kovacek I., Ljubenkov I., Spaventi R., Eckert-Maksic M. Ascorbic acid and 6-deoxy-6-chloro-ascorbic acid: potential anticancer drugs. Neoplasma. 1997; 44:101-107.
    • (1997) Neoplasma , vol.44 , pp. 101-107
    • Osmak, M.1    Kovacek, I.2    Ljubenkov, I.3    Spaventi, R.4    Eckert-Maksic, M.5
  • 25
    • 0027104622 scopus 로고
    • Vitamin C status and cancer: epidemiologic evidence of reduced risk
    • Block G. Vitamin C status and cancer: epidemiologic evidence of reduced risk. Ann NY Acad Sci. 1992; 669:280-290.
    • (1992) Ann NY Acad Sci. , vol.669 , pp. 280-290
    • Block, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.