The relative efficacy of lycopene and β-carotene in inhibiting experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice

Journal of Nutrition

Volumn 138, Issue 11, 2008, Pages 2289-

  Ching, Kuang Chow ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CAROTENE; CASPASE 3; CYCLINE; INDUCIBLE NITRIC OXIDE SYNTHASE; LYCOPENE; METALLOPROTEINASE; NEU DIFFERENTIATION FACTOR; PROTEIN BCL 2; PROTEIN P53; VASCULOTROPIN;

APOPTOSIS; COLON CANCER; DOSE RESPONSE; DRUG INHIBITION; DRUG MEGADOSE; DRUG TISSUE LEVEL; HEPATOMA CELL; LETTER; LOW DRUG DOSE; LUNG METASTASIS; MELANOMA CELL; METASTASIS; NONHUMAN; NUDE MOUSE;

MUS MUSCULUS;

EID: 55949105595     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/138.11.2289     Document Type: Letter

References (6)

1. Huang C-S, Liao J-W, Hu M-L. Lycopene inhibits experimental metastasis of human hepatoma SK-Hep-1 cells in athymic nude mice. J Nutr. 2008;138:538-43.
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3. Guruvayoorappan C, Kuttan G. β-Carotene down-regulates inducible nitric oxide synthase gene expression and induces apoptosis by suppressing bcl-2 expression and activating caspase-3 and p53 genes in B16F210 melanoma cells. Nutr Res. 2007;27:336-42.
4. Palozza P, Serini S, Maggiano N, Tringali G, Navarra P, Ranelletti FO, Calviello G. b-Carotene downregulates the steady-state and heregulin-α- induced COX-2 pathways in colon cancer cells. J Nutr. 2005;135:129-36.
5. Goodman GE, Thornquist MD, Balmes J, Cullen MR, Meyskens FL, Jr., Omenn GS, Valanis B, Williams JH, Jr. The beta-carotene and retinol efficacy trial: incidence of lung cancer and cardiovascular disease mortality during 6-year follow-up after stopping beta-carotene and retinol supplements. J Natl Cancer Inst. 2004;96:1743-50.
6. Russell RM. Beta-carotene and lung cancer. Pure Appl Chem. 2002;74:1461-7.