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Volumn 3, Issue 4, 2008, Pages 393-405

Antivirals: Current state of the art

Author keywords

Approved antiviral; CMV; Experimental antiviral; HBV; HCV; HIV; HSV; Influenza virus; Poxvirus; VZV

Indexed keywords

3 DEAZANEPLANOCIN A; ACICLOVIR; ADENOSYLHOMOCYSTEINASE INHIBITOR; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; BAY 57 1293; BENZIMIDAVIR; BENZODIAZEPINE DERIVATIVE; CANERTINIB; CIDOFOVIR; CMX 001; EFAVIRENZ PLUS EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; FAMCICLOVIR; FAVIPIRAVIR; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; IMATINIB; INTEGRASE INHIBITOR; PEGINTERFERON; PIRODAVIR; PLECONARIL; PROTEINASE INHIBITOR; RIBAVIRIN; RNA DIRECTED DNA POLYMERASE INHIBITOR; RSV 604; SIALIDASE INHIBITOR; ST 246; T 705; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALACICLOVIR; VALGANCICLOVIR;

EID: 55949103581     PISSN: 17460794     EISSN: None     Source Type: Journal    
DOI: 10.2217/17460794.3.4.393     Document Type: Review
Times cited : (31)

References (51)
  • 1
    • 36749073433 scopus 로고    scopus 로고
    • The design of drugs for HIV and HCV
    • De Clercq E: The design of drugs for HIV and HCV. Nat. Rev. Drug Discov. 6, 1001-1018 (2007).
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 1001-1018
    • De Clercq, E.1
  • 2
    • 36749088862 scopus 로고    scopus 로고
    • HIV drug development: The next 25 years
    • Flexner C: HIV drug development: the next 25 years. Nat. Rev. Drug Discov. 6, 959-966 (2007).
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 959-966
    • Flexner, C.1
  • 3
    • 36749037438 scopus 로고    scopus 로고
    • From adefovir to Atripla™ via tenofovir, Viread™ and Truvada™
    • De Clercq E: From adefovir to Atripla™ via tenofovir, Viread™ and Truvada™. Future Virol. 1, 709-715 (2006).
    • (2006) Future Virol , vol.1 , pp. 709-715
    • De Clercq, E.1
  • 4
    • 38549137325 scopus 로고    scopus 로고
    • Antiviral treatment of chronic hepatitis B virus infections: The past, the present and the future
    • Ferir G, Kaptein S, Neyts J, De Clercq E: Antiviral treatment of chronic hepatitis B virus infections: the past, the present and the future. Rev Med. Virol. 18, 19-34 (2008).
    • (2008) Rev Med. Virol , vol.18 , pp. 19-34
    • Ferir, G.1    Kaptein, S.2    Neyts, J.3    De Clercq, E.4
  • 5
    • 34948857943 scopus 로고    scopus 로고
    • Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl]-adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections
    • Painter GR, Almond MR, Trost LC et al.: Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl]-adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections. Antimicrob. Agents Chemother. 51, 3505-3509 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 3505-3509
    • Painter, G.R.1    Almond, M.R.2    Trost, L.C.3
  • 6
    • 0347928672 scopus 로고    scopus 로고
    • Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids
    • Deres K, Schröder CH, Paessens A et al.: Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids. Science 299, 893-896 (2003).
    • (2003) Science , vol.299 , pp. 893-896
    • Deres, K.1    Schröder, C.H.2    Paessens, A.3
  • 7
    • 0344131411 scopus 로고    scopus 로고
    • Development of resistance and perspectives for future therapies against hepatitis B infections: Lessons to be learned from HIV
    • Deres K, Rübsamen-Waigmann H: Development of resistance and perspectives for future therapies against hepatitis B infections: lessons to be learned from HIV. Infection 27, S45-S51 (1999).
    • (1999) Infection , vol.27
    • Deres, K.1    Rübsamen-Waigmann, H.2
  • 8
    • 33751517736 scopus 로고    scopus 로고
    • Antiviral agents active against influenza A viruses
    • De Clercq E: Antiviral agents active against influenza A viruses. Nat. Rev. Drug Discov. 5, 1015-1025 (2006).
    • (2006) Nat. Rev. Drug Discov , vol.5 , pp. 1015-1025
    • De Clercq, E.1
  • 9
    • 36749056771 scopus 로고    scopus 로고
    • The war against influenza: Discovery and development of sialidase inhibitors
    • von Itzstein M: The war against influenza: discovery and development of sialidase inhibitors. Nat. Rev. Drug Discov. 6, 967-974 (2007).
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 967-974
    • von Itzstein, M.1
  • 11
    • 27844455955 scopus 로고    scopus 로고
    • Acyclic nucleoside phosphonates: A key class of antiviral drugs
    • De Clercq E, Holy A: Acyclic nucleoside phosphonates: a key class of antiviral drugs. Nat. Rev. Drug Discov. 4, 928-940 (2005).
    • (2005) Nat. Rev. Drug Discov , vol.4 , pp. 928-940
    • De Clercq, E.1    Holy, A.2
  • 12
    • 38649102173 scopus 로고    scopus 로고
    • Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand
    • Magee WC, Aldern KA, Hostetler KY, Evans DH: Cidofovir and (S)-9-[3-hydroxy-(2-phosphonomethoxy)propyl]adenine are highly effective inhibitors of vaccinia virus DNA polymerase when incorporated into the template strand. Antimicrob. Agents Chemother. 52, 586-597 (2008).
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 586-597
    • Magee, W.C.1    Aldern, K.A.2    Hostetler, K.Y.3    Evans, D.H.4
  • 13
    • 26444587116 scopus 로고    scopus 로고
    • An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus challenge
    • Yang G, Pevear DC, Davies MH et al.: An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus challenge. J. Virol. 79, 13139-13149 (2005).
    • (2005) J. Virol , vol.79 , pp. 13139-13149
    • Yang, G.1    Pevear, D.C.2    Davies, M.H.3
  • 14
    • 33846623695 scopus 로고    scopus 로고
    • Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice
    • Quenelle DC, Buller RML, Parker S et al.: Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice. Antimicrob. Agents Chemother. 51, 689-695 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 689-695
    • Quenelle, D.C.1    Buller, R.M.L.2    Parker, S.3
  • 15
    • 34249742507 scopus 로고    scopus 로고
    • Efficacy of the antipoxvirus compound ST-246 for treatment of severe orthopoxvirus infection
    • Sbrana E, Jordan R, Hruby DE et al.: Efficacy of the antipoxvirus compound ST-246 for treatment of severe orthopoxvirus infection. Am. J. Trop. Med. Hyg. 76, 768-773 (2007).
    • (2007) Am. J. Trop. Med. Hyg , vol.76 , pp. 768-773
    • Sbrana, E.1    Jordan, R.2    Hruby, D.E.3
  • 16
    • 14944382916 scopus 로고    scopus 로고
    • Antiviral chemotherapy facilitates control of poxvirus infections through inhibition of cellular signal transduction
    • Yang H, Kim SK, Kim M et al.: Antiviral chemotherapy facilitates control of poxvirus infections through inhibition of cellular signal transduction. J. Clin. Invest. 115, 379-387 (2005).
    • (2005) J. Clin. Invest , vol.115 , pp. 379-387
    • Yang, H.1    Kim, S.K.2    Kim, M.3
  • 17
    • 22544470270 scopus 로고    scopus 로고
    • Disabling poxvirus pathogenesis by inhibition of Abi-family tyrosine kinases
    • Reeves PM, Bommarius B, Lebeis S et al.: Disabling poxvirus pathogenesis by inhibition of Abi-family tyrosine kinases. Nat. Med. 11, 731-739 (2005).
    • (2005) Nat. Med , vol.11 , pp. 731-739
    • Reeves, P.M.1    Bommarius, B.2    Lebeis, S.3
  • 18
    • 36749040780 scopus 로고    scopus 로고
    • Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models
    • Duraffour S, Snoeck R, Kremerová M et al.: Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models. Antimicrob. Agents Chemother. 51, 4410-4419 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 4410-4419
    • Duraffour, S.1    Snoeck, R.2    Kremerová, M.3
  • 19
    • 35848929516 scopus 로고    scopus 로고
    • Effect of oral treatment with hexadecyloxypropyl-[(S)-9-(3-hydroxy-2- phosphonylmethoxypropyl)adenine] [(S)-HPMPA] or octadecyloxyethyl-(S)-HPMPA on cowpox or vaccinia virus infections in mice
    • Quenelle DC, Collins DJ, Herrod BP et al.: Effect of oral treatment with hexadecyloxypropyl-[(S)-9-(3-hydroxy-2- phosphonylmethoxypropyl)adenine] [(S)-HPMPA] or octadecyloxyethyl-(S)-HPMPA on cowpox or vaccinia virus infections in mice. Antimicrob. Agents Chemother., 3940-3947 (2007).
    • (2007) Antimicrob. Agents Chemother , pp. 3940-3947
    • Quenelle, D.C.1    Collins, D.J.2    Herrod, B.P.3
  • 20
    • 33847083535 scopus 로고    scopus 로고
    • Hostetler KY, Beadle JR, Trahan J et al.: Oral 1-O-octadecyl-2-[i O-benzyl-sn-glycero-3-cidofovir targets the lung and is effective against a lethal respiratory challenge with ectromelia virus in mice. Antiviral Res. 73, 212-218 (2007).
    • Hostetler KY, Beadle JR, Trahan J et al.: Oral 1-O-octadecyl-2-[i O-benzyl-sn-glycero-3-cidofovir targets the lung and is effective against a lethal respiratory challenge with ectromelia virus in mice. Antiviral Res. 73, 212-218 (2007).
  • 21
    • 35848968505 scopus 로고    scopus 로고
    • Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses
    • Quenelle DC, Prichard MN, Keith KA et al.: Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses. Antimicrob. Agents Chemother. 51, 4118-4124 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 4118-4124
    • Quenelle, D.C.1    Prichard, M.N.2    Keith, K.A.3
  • 22
    • 35948949782 scopus 로고    scopus 로고
    • RSV604, a novel inhibitor of respiratory syncytial virus replication
    • Chapman J, Abbott E, Alber DG et al.: RSV604, a novel inhibitor of respiratory syncytial virus replication. Antimicrob. Agents Chemother. 51, 3346-3353 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 3346-3353
    • Chapman, J.1    Abbott, E.2    Alber, D.G.3
  • 23
    • 0036107516 scopus 로고    scopus 로고
    • Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease
    • Crute JJ, Grygon CA, Hargrave KD et al.: Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease. Nat. Med. 8, 386-391 (2002).
    • (2002) Nat. Med , vol.8 , pp. 386-391
    • Crute, J.J.1    Grygon, C.A.2    Hargrave, K.D.3
  • 24
    • 0036111626 scopus 로고    scopus 로고
    • New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease
    • Kleymann G, Fischer R, Betz UA et al.: New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease. Nat. Med. 8, 392-398 (2002).
    • (2002) Nat. Med , vol.8 , pp. 392-398
    • Kleymann, G.1    Fischer, R.2    Betz, U.A.3
  • 26
    • 33947286682 scopus 로고    scopus 로고
    • Superior efficacy of helicase-primase inhibitor BAY 57-1293 for herpes infection and latency in the guinea pig model of human genital herpes disease
    • Baumeister J, Fischer R, Eckenberg P, Henninger K, Ruebsamen-Waigmann H, Kleymann G: Superior efficacy of helicase-primase inhibitor BAY 57-1293 for herpes infection and latency in the guinea pig model of human genital herpes disease. Antiviral Chem. Chemother. 18, 35-48 (2007).
    • (2007) Antiviral Chem. Chemother , vol.18 , pp. 35-48
    • Baumeister, J.1    Fischer, R.2    Eckenberg, P.3    Henninger, K.4    Ruebsamen-Waigmann, H.5    Kleymann, G.6
  • 27
    • 33947241644 scopus 로고    scopus 로고
    • The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1
    • Biswas S, Jennens L, Field HJ: The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1. Antiviral Res. 75, 30-35 (2007).
    • (2007) Antiviral Res , vol.75 , pp. 30-35
    • Biswas, S.1    Jennens, L.2    Field, H.J.3
  • 28
    • 8644267364 scopus 로고    scopus 로고
    • Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase
    • Liuzzi M, Kibler P, Bousquet C et al.: Isolation and characterization of herpes simplex virus type 1 resistant to aminothiazolylphenyl-based inhibitors of the viral helicase-primase. Antiviral Res. 64, 161-170 (2004).
    • (2004) Antiviral Res , vol.64 , pp. 161-170
    • Liuzzi, M.1    Kibler, P.2    Bousquet, C.3
  • 29
    • 34547837615 scopus 로고    scopus 로고
    • Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1
    • Biswas S, Smith C, Field HJ: Detection of HSV-1 variants highly resistant to the helicase-primase inhibitor BAY 57-1293 at high frequency in 2 of 10 recent clinical isolates of HSV-1. J. Antimicrob. Chemother. 60, 274-279 (2007).
    • (2007) J. Antimicrob. Chemother , vol.60 , pp. 274-279
    • Biswas, S.1    Smith, C.2    Field, H.J.3
  • 30
    • 33947220269 scopus 로고    scopus 로고
    • High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1
    • Biswas S, Swift M, Field HJ: High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293) drug-resistant variants in certain laboratory isolates of HSV-1. Antiviral Chem. Chemother. 18, 13-23 (2007).
    • (2007) Antiviral Chem. Chemother , vol.18 , pp. 13-23
    • Biswas, S.1    Swift, M.2    Field, H.J.3
  • 31
    • 0037404522 scopus 로고    scopus 로고
    • Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo [2,3-d]pyrimidine nucleoside analogues
    • De Clercq E: Highly potent and selective inhibition of varicella-zoster virus replication by bicyclic furo [2,3-d]pyrimidine nucleoside analogues. Med. Res. Rev. 23, 253-274 (2003).
    • (2003) Med. Res. Rev , vol.23 , pp. 253-274
    • De Clercq, E.1
  • 32
    • 36448956849 scopus 로고    scopus 로고
    • Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitros of varicella zoster virus
    • McGuigan C, Pathirana RN, Migliore M et al.: Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitros of varicella zoster virus. J. Antimicrob. Chemother. 60. 1316-1330 (2007).
    • (2007) J. Antimicrob. Chemother , vol.60 , pp. 1316-1330
    • McGuigan, C.1    Pathirana, R.N.2    Migliore, M.3
  • 33
    • 14744269097 scopus 로고    scopus 로고
    • Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides
    • Andrei G, Sienaert R, McGuigan C, De Clercq E, Balzarini J, Snoeck R: Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides. Antimicrob. Agents Chemother. 49, 1081-1086 (2005).
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 1081-1086
    • Andrei, G.1    Sienaert, R.2    McGuigan, C.3    De Clercq, E.4    Balzarini, J.5    Snoeck, R.6
  • 34
    • 33747141729 scopus 로고    scopus 로고
    • Antiviral drugs for cytomegalovirus diseases
    • Biron KK: Antiviral drugs for cytomegalovirus diseases. Antiviral Res. 71, 154-163 (2006).
    • (2006) Antiviral Res , vol.71 , pp. 154-163
    • Biron, K.K.1
  • 35
    • 37349039721 scopus 로고    scopus 로고
    • Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant
    • Chou S, Marousek GI: Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant. J. Virol. 82, 246-253 (2008).
    • (2008) J. Virol , vol.82 , pp. 246-253
    • Chou, S.1    Marousek, G.I.2
  • 36
    • 0035050725 scopus 로고    scopus 로고
    • Inhibition of murine cytomegalovirus and human cytomegalovirus by a novel non-nucleoside compound in vivo
    • Weber O, Bender W, Eckenberg P et al.: Inhibition of murine cytomegalovirus and human cytomegalovirus by a novel non-nucleoside compound in vivo. Antiviral Res. 49, 179-189 (2001).
    • (2001) Antiviral Res , vol.49 , pp. 179-189
    • Weber, O.1    Bender, W.2    Eckenberg, P.3
  • 37
    • 0035656411 scopus 로고    scopus 로고
    • Novel non-nucleoside inhibitors of cytomegalovirus (BAY 38-4766): In vitro and in vivo antiviral activity and mechanism of action
    • Reefschläger J, Bender W, Hallenberger S et al.: Novel non-nucleoside inhibitors of cytomegalovirus (BAY 38-4766): in vitro and in vivo antiviral activity and mechanism of action. J. Antimicrob. Chemother. 48, 757-767 (2001).
    • (2001) J. Antimicrob. Chemother , vol.48 , pp. 757-767
    • Reefschläger, J.1    Bender, W.2    Hallenberger, S.3
  • 38
    • 0034855634 scopus 로고    scopus 로고
    • A novel nonnucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products
    • Buerger J, Reefschläger J, Bender W et al.: A novel nonnucleoside inhibitor specifically targets cytomegalovirus DNA maturation via the UL89 and UL56 gene products. J. Virol. 75, 9077-9086 (2001).
    • (2001) J. Virol , vol.75 , pp. 9077-9086
    • Buerger, J.1    Reefschläger, J.2    Bender, W.3
  • 39
    • 34548031594 scopus 로고    scopus 로고
    • In search of effective anti-HHV-6 agents
    • De Clercq E, Naesens L: In search of effective anti-HHV-6 agents. J. Clin. Virol. 47, S82-S86 (2006).
    • (2006) J. Clin. Virol , vol.47
    • De Clercq, E.1    Naesens, L.2
  • 40
    • 34247225861 scopus 로고    scopus 로고
    • Antiviral activity of diverse classes of broad-acting agents and natural compounds in HHV-6-infected lymphoblasts
    • Naesens L, Bonnafous P, Agut H, De Clercq E: Antiviral activity of diverse classes of broad-acting agents and natural compounds in HHV-6-infected lymphoblasts. J. Clin. Virol. 37(Suppl. 1), S69-S75 (2006).
    • (2006) J. Clin. Virol , vol.37 , Issue.SUPPL. 1
    • Naesens, L.1    Bonnafous, P.2    Agut, H.3    De Clercq, E.4
  • 41
    • 34249089649 scopus 로고    scopus 로고
    • Origins of major human infectious diseases
    • Wolfe ND, Dunavan CP, Diamond J: Origins of major human infectious diseases. Nature 447, 279-283 (2007).
    • (2007) Nature , vol.447 , pp. 279-283
    • Wolfe, N.D.1    Dunavan, C.P.2    Diamond, J.3
  • 42
    • 35948957769 scopus 로고    scopus 로고
    • In vitro and in vivo activities of T-705 against arenavirus and bunyavirus infections
    • Gowen BB, Wong MH, Jung KH et al.: In vitro and in vivo activities of T-705 against arenavirus and bunyavirus infections. Antimicrob. Agents Chemother. 51, 3168-3176 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 3168-3176
    • Gowen, B.B.1    Wong, M.H.2    Jung, K.H.3
  • 43
    • 0035997942 scopus 로고    scopus 로고
    • 3-deazaneplanocin A induces massively increased interferon-α production in Ebola virus-infected mice
    • Bray M, Raymond JL, Geisbert T, Baker RO: 3-deazaneplanocin A induces massively increased interferon-α production in Ebola virus-infected mice. Antiviral Res. 55, 151-159 (2002).
    • (2002) Antiviral Res , vol.55 , pp. 151-159
    • Bray, M.1    Raymond, J.L.2    Geisbert, T.3    Baker, R.O.4
  • 45
    • 0022630892 scopus 로고
    • Lacsa fever. Effective therapy with ribavirin
    • McCormick JB, King IJ, Webb PA et al.: Lacsa fever. Effective therapy with ribavirin. N. Engl. J. Med. 314, 20-26 (1986).
    • (1986) N. Engl. J. Med , vol.314 , pp. 20-26
    • McCormick, J.B.1    King, I.J.2    Webb, P.A.3
  • 46
    • 42049112379 scopus 로고    scopus 로고
    • Potential use of antiviral agents in polio eradication
    • De Palma AM. Pürstinger G, Wimmer E et al.: Potential use of antiviral agents in polio eradication. Emerg. Infect. Dis. 14, 545-551 (2008).
    • (2008) Emerg. Infect. Dis , vol.14 , pp. 545-551
    • De Palma, A.M.1    Pürstinger, G.2    Wimmer, E.3
  • 47
    • 4444256678 scopus 로고    scopus 로고
    • Antivirals and antiviral strategies
    • De Clercq E: Antivirals and antiviral strategies. Nat. Rev. Microbiol. 2, 704-720 (2004).
    • (2004) Nat. Rev. Microbiol , vol.2 , pp. 704-720
    • De Clercq, E.1
  • 48
    • 33645102511 scopus 로고    scopus 로고
    • The anti-yellow fever virus activity of ribavirin is independent of error-prone replication
    • Leyssen P, De Clercq E, Neyts J: The anti-yellow fever virus activity of ribavirin is independent of error-prone replication. Mol. Pharmacol. 69, 1461-1467 (2006).
    • (2006) Mol. Pharmacol , vol.69 , pp. 1461-1467
    • Leyssen, P.1    De Clercq, E.2    Neyts, J.3
  • 49
    • 33845992567 scopus 로고    scopus 로고
    • Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5′ -triphosphate, not with inhibition of IMP dehydrogenase
    • Sun Y, Chung D-H, Chu Y-K, Jonsson CB, Parker WB: Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5′ -triphosphate, not with inhibition of IMP dehydrogenase. Antimicrob. Agents Chemother. 51, 84-88 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , pp. 84-88
    • Sun, Y.1    Chung, D.-H.2    Chu, Y.-K.3    Jonsson, C.B.4    Parker, W.B.5
  • 51
    • 36749069393 scopus 로고    scopus 로고
    • Interferons at age 50: Past, current and future impact on biomedicine
    • Borden EC, Sen GC, Uze G et al.: Interferons at age 50: past, current and future impact on biomedicine. Nat. Rev. Drug Discov. 6, 975-990 (2007).
    • (2007) Nat. Rev. Drug Discov , vol.6 , pp. 975-990
    • Borden, E.C.1    Sen, G.C.2    Uze, G.3


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