Controversies in the role of SLC26 anion exchangers in pancreatic ductal bicarbonate secretion

Pancreas

Volumn 37, Issue 2, 2008, Pages 232-234

  Hegyi, Péter ^a   Rakonczay, Zoltán ^a   Farkas, Klaudia ^a   Venglovecz, Viktória ^a   Ózsvari, Béla ^a   Seidler, Ursula ^b   Gray, Mike A ^c   Argent, Barry E ^c  

^a UNIVERSITY OF SZEGED   (Hungary)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; MEMBRANE PROTEIN; PROTON; SLC26 ANION EXCHANGER PROTEIN; SODIUM PROTON EXCHANGE PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG; ANION TRANSPORT PROTEIN;

ANION EXCHANGE; COMPETITIVE INHIBITION; GENE MUTATION; HUMAN; LETTER; NONHUMAN; PANCREAS DUCT; PANCREAS JUICE; PANCREAS SECRETION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON TRANSPORT; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT;

ANIMALS; ANION TRANSPORT PROTEINS; BICARBONATES; HUMANS; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PANCREATIC DUCTS;

EID: 55949101122     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e318164f8ff     Document Type: Letter

References (10)

1. Steward MC, Ishiguro H, Case RM. Mechanisms of bicarbonate secretion in the pancreatic duct. Ann Rev Physiol. 2005;67: 377-409.
2. Argent BE, Gray MA, Steward MC, et al. Cel physiology of pancreatic ducts. In: Johnson LR, ed. Physiology of the Gastrointestinal Tract. 4th ed. San Diego, CA: Elsevier; 2006:1371-1396.
3. Ishiguro H, Steward MC, Sohma Y, et al. Membrane potential and bicarbonate secretion in isolated interlobular ducts from guinea-pig pancreas. J Gen Physiol. 2002;120:617-628.
4. - transport in a mathematical model of the pancreatic ductal epithelium. J Membr Biol. 2000;176:77-100.
5. Ko SB, Zeng W, Dorwart MR, et al. Gating of CFTR by the STAS domain of SLC26 transporters. Nat Cell Biol. 2004;6:343-350.
6. Mount D, Romero M. The SLC26 gene family of multifunctional anion exchangers. Pflügers Arch. 2004;447:710-721.
7. -exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct. Am J Physiol. 2007;292: G447-G455.
8. - secretion: relevance to cystic fibrosis. EMBO J. 2006;25:5049-5057.
9. - exchange by slc26a3 and slc26a6. J Gen Physiol. 2006;127: 511-524.
10. Rakonczay Z, Hegyi P, Hasegawa M, et al. CFTR gene transfer to human cystic fibrosis pancreatic duct cells using a Sendai virus vector. J Cell Physiol. 2008; 214:442-455.