Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome

British Journal of Cancer

Volumn 99, Issue 10, 2008, Pages 1726-1728

  Vickaryous, N ^a   Polanco Echeverry, G ^a   Morrow, S ^a   Suraweera, N ^a   Thomas, H ^b   Tomlinson, I ^c   Silver, A ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b ST MARK S HOSPITAL   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Hereditary non polyposis colorectal cancer; Microsatellite instability; Smooth muscle myosin

Indexed keywords

MUTANT PROTEIN; MYOSIN;

ARTICLE; CANCER GENETICS; COLORECTAL ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; FRAMESHIFT MUTATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ADENOMA; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; FRAMESHIFT MUTATION; HUMANS; MICROSATELLITE INSTABILITY; MYOSIN HEAVY CHAINS; SMOOTH MUSCLE MYOSINS;

EID: 55949087731     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604737     Document Type: Article

References (9)

1. Alhopuro P, Phichith D, Tuupanen S, Sammalkorpi H, Nybondas M, Saharinen J, Robinson JR, Yang Z, Chen LQ, Orntoft T, Mecklin JP, Jarvinen H, Eng C, Moeslein G, Shibata D, Houlston RS, Lucassen A, Tomlinson I, Launonen V, Ristimaki A, Arango D, Karhu A, Sweeney HL, Aaltonen L (2008) Unregulated smooth-muscle myosin in human intestinal neoplasia. PNAS 105: 5513-5518, doi:10.1073/pnas.0801213105
2. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN, Srivastava S (1998) A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248-5257
3. Johannsdottir JT, Jonasson JG, Bergthorsson JT, Amundadottir LT, Magnusson J, Egilsson V, Ingvarsson S (2000) The effect of mismatch repair deficiency on tumourigenesis; microsatellite instability affecting genes containing short repeated sequences. Int J Oncol 16: 133-139
4. Johnson V, Lipton LR, Cummings C, Eftekhar Sadat ET, Izatt L, Hodgson SV, Talbot I, Thomas HJ, Silver A, Tomlinson IP (2005a) Analysis of somatic molecular changes, clinicopathological features, family history and germline mutations in colorectal families: evidence for efficient diagnosis of HNPCC and for distinct groups of non-HNPCC families. J Med Genet 42: 756-762
5. Johnson V, Volikos E, Halford S, Eftekhar Sadat ET, Popat S, Talbot I, Truninger K, Martin J, Jass J, Houlston R, Atkin W, Tomlinson IP, Silver AR (2005b) Exon 3 beta-catenin mutations are specifically associated with colorectal carcinomas in the hereditary non-polyposis colorectal cancer syndrome. Gut 54: 264-267, doi:10.1136/gut.2004.048132
6. Lagerstedt Robinson K, Liu T, Vandrovcova J, Halvarsson B, Clendenning M, Frebourg T, Papadopoulos N, Kinzler KW, Vogelstein B, Peltomaki P, Kolodner RD, Nilbert M, Lindbolm A (2007) Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics. J Natl Cancer Inst 99: 291-299
7. Liu B, Parsons R, Papadopoulos N, Nicolaides NC, Lynch HT, Watson P, Jass JR, Dunlop M, Wyllie A, Peltomaki P, de la Chapelle A, Hamilton SR, Vogelstein B, Kinzler KW (1996) Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nat Med 2: 169-174
8. Loughrey MB, Waring PM, Tan A, Trivett M, Kovalenko S, Beshay V, Young MA, McArthur G, Boussioutas A, Dobrovic A (2007) Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer. Fam Cancer 6: 01-10, doi:10.1007/s10689-007-9124-1
9. Lynch HT, Smyrk T (1996) Hereditary nonpolyposis colorectal cancer (Lynch syndrome). An updated review. Cancer (Phila) 78: 1149-1167